Results 161 to 170 of about 102,308 (347)

Neuropathological and cerebrospinal fluid correlates of choroid plexus inflammation in progressive multiple sclerosis

open access: yesBrain Pathology, EarlyView.
Graphical representation of the widespread white matter (blue color mask) and grey matter (cortical and deep grey matter; red color mask) demyelination in MS cases characterized by substantial inflammation of the CP (A). The presence of lesions was mainly associated with periventricular white matter and hippocampus areas (A).
R. Magliozzi   +19 more
wiley   +1 more source

Monoclonal antibodies against porcine platelet membrane glycoproteins Ib and IIb/IIIa [PDF]

open access: bronze, 1988
Hidenobu Takami   +5 more
openalex   +1 more source

Progress on the development of Class A GPCR‐biased ligands

open access: yesBritish Journal of Pharmacology, EarlyView.
Class A G protein‐coupled receptors (GPCRs) continue to garner interest for their essential roles in cell signalling and their importance as drug targets. Although numerous drugs in the clinic target these receptors, over 60% GPCRs remain unexploited. Moreover, the adverse effects triggered by the available unbiased GPCR modulators, limit their use and
Paula Morales   +20 more
wiley   +1 more source

Mesenchymal Stem Cell‐Derived Exosomes: A Promising Therapeutic Strategy for Age‐Related Diseases

open access: yesCell Proliferation, EarlyView.
Mechanisms of MSC‐Exos in the treatment of age‐related diseases. A Immunomodulatory and anti‐inflammatory, MSC‐Exos mediate immunomodulatory and anti‐inflammatory effects by regulating the polarisation of T cells and macrophages, promoting an anti‐inflammatory state while inhibiting pro‐inflammatory responses; B Suppression of oxidative stress, MSC ...
Bohua Wei   +5 more
wiley   +1 more source

Asociación de la púrpura trombocitopénica inmunológica y el síndrome de Guillain-Barré. A propósito de un caso: with regard to a case Association of immunologic thrombocytopenia and the Guillain-Barré syndrome

open access: yesRevista Cubana de Hematología, Inmunología y Hemoterapia, 2010
La púrpura trombocitopénica inmunológica es una enfermedad autoinmune, benigna, de aparición frecuente, caracterizada por la presencia de anticuerpos dirigidos contra las glicoproteínas de la membrana plaquetaria que producen una disminución del recuento
Dunia de la C. Castillo-González   +3 more
doaj  

The Interaction Between Vasculogenic Mimicry and the Immune System: Mechanistic Insights and Dual Exploration in Cancer Therapy

open access: yesCell Proliferation, EarlyView.
VM is a novel form of angiogenesis discovered in many malignant tumours in recent years. And the well‐known immune response and related immune cells play different regulatory roles in the formation of VM. ABSTRACT Vasculogenic mimicry (VM) represents a novel form of angiogenesis discovered in numerous malignant tumours in recent years.
Shutong Liu   +14 more
wiley   +1 more source

New Anti‐Fibrotic Strategies for Keloids: Insights From Single‐Cell Multi‐Omics

open access: yesCell Proliferation, EarlyView.
Our research not only revealed the ubiquity and activity of POSTN‐positive mesenchymal fibroblasts in keloids but also discovered the predominant role of IGFBP2‐positive fibroblasts in normal skin and their potential significance in the process of anti‐fibrotic therapy.
Songyun Zhao   +16 more
wiley   +1 more source

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