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Platelet membrane glycoproteins
Thrombosis Research, 1996 Inherited giant platelet disorders (IGPD) are a heterogeneous group of rare diseases characterized by thrombocytopenia, large platelets and variable bleeding symptoms. Glycoprotein (GP) expression on platelet surface in these conditions is poorly characterized. We have investigated the expression of constitutively expressed platelet membrane GP and the
Sílvia, Pérez-Pujol +5 more
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The Clinical Significance of Platelet Membrane Glycoproteins
Hematology/Oncology Clinics of North America, 1990To mediate their hemostatic functions, platelets must adhere to exposed vascular subendothelium and then aggregate. A variety of membrane glycoprotein receptors for adhesive ligands are present on platelets that promote adhesion and aggregation. Analysis of congenital disorders of platelet glycoproteins has been instrumental in clarifying our knowledge
Rodger P Mcever
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Platelet Membrane Glycoproteins: Functions in Cellular Interactions
Annual Review of Cell Biology, 1990The understanding of the structure and function of platelet membrane glycoproteins has been facilitated by studies showing that they belong to larger gene families of cell surface receptors involved in cellular interactions. In some instances (e.g. GP IIb-IIIa and GP Ib-IX) the study of the platelet proteins has served as a prototype for relatively ...
N, Kieffer, D R, Phillips
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Expression of platelet parameters and platelet membrane glycoproteins in childhood Burkitt lymphoma
Leukemia Research, 2019Platelet activation and functional changes in some haematological malignancies have been investigated with little or no known documentation on Burkitt lymphoma (BL). Abnormalities of platelets contribute to either haemorrhage or thrombotic episodes which are life-threatening in patients with BL.
Renate Asare +10 more
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Platelet Membrane Glycoproteins
, 2017 Platelets are small anucleate blood cells that are produced in the bone marrow from the cytoplasm of megakaryocytes. Circulating platelets are essential for primary hemostasis and also involved in pathological thrombosis. For the platelet hemostatic functions, platelet surface membrane glycoproteins are crucial to form platelet-subendothelial matrix ...
Hisashi Kato, Yoshiaki Tomiyama
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Membrane Glycoproteins in Cryopreserved Platelets
Vox Sanguinis, 1994AbstractAlthough platelets stored by cryopreservation are effective in hemostasis, they acquire a number of functional defects during storage and preparation for transfusion. In addition to known acquired defects such as defective aggregation, decreased resistance to hypotonic shock, and disc‐spherocyte transformation, we have shown that cryopreserved ...
M, Owens +3 more
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