Results 41 to 50 of about 107,646 (331)

Transfusion efficacy and influencing factors of patients transfused with different therapeutic doses of platelets: a comparative analysis

Zhongguo shuxue zazhi
[Objective] To compare and analyze the efficacy of platelet transfusion in patients with different doses, and to analyze the risk factors for platelet transfusion refractoriness.
ZHU Jianling, CHENG Tingting, MA Chunya, FU Lihui, SHI Hongmei, YU Yang   +5 more
doaj   +1 more source

Structure and thermodynamics of platelet dispersions [PDF]

Molec. Phys. 106, 1975 (2008), 2008
Various properties of fluids consisting of platelike particles differ from the corresponding ones of fluids consisting of spherical particles because interactions between platelets depend on their mutual orientations. One of the main issues in this topic is to understand how structural properties of such fluids depend on factors such as the shape of ...
arxiv   +1 more source

Treatment of critical bleeding events in patients with immune thrombocytopenia: a protocol for a systematic review and meta-analysis

Systematic Reviews
Background Critical bleeding events in adults and children with ITP are medical emergencies; however, evidence-based treatment protocols are lacking. Due to the severe thrombocytopenia, (typically platelet count less than 20 × 109/L), a critical bleed ...
Emily Sirotich, Hasmik Nazaryan, Saifur Rahman Chowdhury, Gordon Guyatt, Arnav Agarwal, Russell Leong, Aaron Wen, Emily Xu, Bonnie Liu, Sushmitha Pallapothu, Preksha Rathod, Henry Y. Kwon, Jared Dookie, Amirmohammad Shafiee, Jay Charness, Jennifer DiRaimo, Dale Paynter, Barbara Pruitt, Gail Strachan, Rachel Couban, Zhikang Ye, Donald M. Arnold   +21 more
doaj   +1 more source

Platelet Transfusion: And Update on Challenges and Outcomes

Journal of Blood Medicine, 2020
Pilar Solves Alcaina Blood Bank, Hematology Service, Hospital Universitari I Politècnic La Fe, Valencia, CIBERONC, Instituto Carlos III, Madrid, SpainCorrespondence: Pilar Solves AlcainaBlood Bank, Hematology Service, Hospital Universitari I Polit&
Solves Alcaina P
doaj  

Platelet antibodies in immune thrombocytopenia and related conditions

Journal of Laboratory Medicine, 2020
Platelet autoantibodies are a common finding in immune thrombocytopenia (ITP) and in rare cases of antibody-mediated platelet function (“acquired thrombasthenia”).
Kiefel Volker
doaj   +1 more source

Biomarkers of Complement and Platelet Activation are not correlated with the One or Twenty-Four Hours Corrected Count Increments in Prophylactically Platelet Transfused Hematological Patients: a Prospective Cohort Study

Platelets, 2022
Platelet transfusion refractoriness is a serious clinical concern that complicates the management of thrombocytopenic patients. Previous studies have suggested a potential role for both complement and platelet activation based on in vitro analyses of ...
Alexander Åkesson, Marcus Ljungkvist, Myriam Martin, Anna M. Blom, Jenny Klintman, Ulf Schött, Eva Zetterberg, Thomas Kander   +7 more
doaj   +1 more source

Efficient Generation of Megakaryocyte Progenitors and Platelets From HSPCs via JAK2/STAT3 Signaling

Advanced Science, EarlyView.
This research presents a novel strategy employing the VGM cocktail, which combines HES7 overexpression with HDAC inhibitor and GABA, to enhance platelet production from hematopoietic stem and progenitor cells by promoting megakaryocyte progenitor (MkP) generation.
Huicong Liu, Lingna Wang, Jiaqing Liu, Haitao Yuan, Kaiqing Zhang, Yun Qiu, Fangfang Zhu   +6 more
wiley   +1 more source

Three-dimensional Multiscale Model of Deformable Platelets Adhesion to Vessel Wall in Blood Flow [PDF]

, 2013
When a blood vessel ruptures or gets inflamed, the human body responds by rapidly forming a clot to restrict the loss of blood. Platelets aggregation at the injury site of the blood vessel occurring via platelet-platelet adhesion, tethering and rolling on the injured endothelium is a critical initial step in blood clot formation.
arxiv   +1 more source

Dynamic Formation of Preferentially Lattice Oriented, Self Trapped Hydrogen Clusters [PDF]

arXiv, 2023
A series of MD and DFT simulations were performed to investigate hydrogen self-clustering and retention in tungsten. Using a newly develop machine learned interatomic potential, spontaneous formation of hydrogen platelets was observed after implanting low-energy hydrogen into tungsten at high fluxes and temperatures.
arxiv  

Nationwide Trends in Short‐Term Outcomes After Low Anterior Resection for Rectal Cancer: A Pre‐ and Post‐COVID‐19 Analysis From the Japanese National Clinical Database, 2018–2023

Annals of Gastroenterological Surgery, EarlyView.
Despite initial challenges, the healthcare system of Japan effectively managed rectal cancer surgeries during and after the COVID‐19 pandemic. Robotic surgery became more widely adopted, and complication rates improved, demonstrating resilience and adaptability in surgical care.
Ryo Seishima, Hideki Endo, Hiromichi Maeda, Taizo Hibi, Masashi Takeuchi, Yusuke Takemura, Hiroyuki Yamamoto, Akinobu Taketomi, Yoshihiro Kakeji, Yasuyuki Seto, Hideki Ueno, Masaki Mori, Ken Shirabe, Yuko Kitagawa   +13 more
wiley   +1 more source