Rupture Forces among Human Blood Platelets at different Degrees of Activation [PDF]
Little is known about mechanics underlying the interaction among platelets during activation and aggregation. Although the strength of a blood thrombus has likely major biological importance, no previous study has measured directly the adhesion forces of single platelet-platelet interaction at different activation states.
arxiv +1 more source
New approaches to preparation and storage of platelets [PDF]
During the last century, transfusion of blood components has become a prerequisite for treatment in many clinical settings. The availability of plastic bags and methods for centrifugation and separation of blood cells, has enabled processing of whole ...
Larsson, Stella
core +1 more source
Sanguine: Visual Analysis for Patient Blood Management [PDF]
Blood transfusion is a frequently performed medical procedure in surgical and nonsurgical contexts. Although it is frequently necessary or even life-saving, it has been identified as one of the most overused procedures in hospitals. Unnecessary transfusions not only waste resources but can also be detrimental to patient outcomes.
arxiv +1 more source
Efficacy of apheresis platelet transfusion in 310 patients with haematological diseases
Objective To observe the effect of platelet transfusion in inpatients with haematological diseases, analyze the possible causes of platelet transfusion refractoriness (PTR), in order to further improve the efficacy of platelet transfusion.
Shisong YOU+5 more
doaj +1 more source
Platelet transfusions have contributed to the revolutionary modern treatment of hypoproliferative thrombocytopenia. Despite the long-term application of platelet transfusion in therapeutics, all aspects of their optimal use (i.e., in cases of ABO and/or ...
Serena Valsami+4 more
doaj +1 more source
Demand Forecasting for Platelet Usage: from Univariate Time Series to Multivariate Models [PDF]
Platelet products are both expensive and have very short shelf lives. As usage rates for platelets are highly variable, the effective management of platelet demand and supply is very important yet challenging. The primary goal of this paper is to present an efficient forecasting model for platelet demand at Canadian Blood Services (CBS).
arxiv
Platelet antibody detection by flow cytometry: an effective method to evaluate and give transfusional support in platelet refractoriness [PDF]
BACKGROUND: Immune platelet refractoriness is mainly caused by human leukocyte antigen antibodies (80-90% of cases) and, to a lesser extent, by human platelet antigen antibodies.
Avelino, Thayna Mendonca+5 more
core +2 more sources
Immersed boundary simulations of cell-cell interactions in whole blood [PDF]
We present a new method for the geometric reconstruction of elastic surfaces simulated by the immersed boundary method with the goal of simulating the motion and interactions of cells in whole blood. Our method uses parameter-free radial basis functions for high-order meshless parametric reconstruction of point clouds and the elastic force computations
arxiv +1 more source
Management of patients refractory to platelet transfusion [PDF]
Abstract Objective.—To present a current assessment and practical approach to the diagnosis and management of patients who are refractory to platelet transfusions. Design.—A task force was convened by the College of American Pathologists under the auspices of the Transfusion Medicine Resource Committee for the purposes of outlining current concepts in ...
openaire +2 more sources
Platelet kinetics after slow versus standard transfusions: A pilot study [PDF]
Background. Platelet transfusion is required in the acute phase of some thrombocytopenic disorders in order to prevent potentially dangerous hemorrhages.
Abbas Habibi+18 more
core +2 more sources