Results 251 to 260 of about 790,517 (360)

First Indian initiative for preparation of low-titer group “O” single-donor platelets with platelet additive solution

, 2018
Anita Tendulkar, Puneet Jain, Abhaykumar Malind Gupta   +2 more
openalex   +1 more source

Platelets and platelet-derived extracellular vesicles: their role in lung cancer dissemination and premetastatic niche formation. [PDF]

Front Immunol
Locatelli C, Ferrario N, Fortunato O, Ghidotti P, Crescitelli R.   +4 more
europepmc   +1 more source

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

The Long-Term Effects of Pitavastatin on Blood Lipids and Platelet Activation Markers in Stroke Patients: Impact of the Homocysteine Level

, 2014
Hideki Sugimoto, Shingo Konno, Nobuatsu Nomoto, Hiroshi Nakazora, Mayumi Murata, Hisao Kitazono, Tomomi Imamura, Masashi Inoue, Miyuki Sasaki, Akihisa Fuse, Wataru Hagiwara, M. Kobayashi, Toshiki Fujioka   +12 more
openalex   +2 more sources

Arterial human blood flow can be stopped by cables of VWF and platelets without coagulation. [PDF]

Blood Adv
Machenaud ELV, Weisel JW, Litvinov RI, Nagaswami C, Ku DN.   +4 more
europepmc   +1 more source

Platelet Rubicon Bidirectional Regulation of GPVI and Integrin αIIbβ3 Signaling Mitigates Stroke Infarction Without Compromising Hemostasis

Advanced Science, EarlyView.
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen, Jingke Li, Yangyang Liu, Li Li, Xin Deng, Yilin Sheng, Xianyu Zhu, Xiao Jiang, Wei Li, Xueli Cai, Qiming Sun, Hu Hu   +11 more
wiley   +1 more source

Preclinical evaluation on human platelet lysate for the treatment of secondary injury following intracerebral hemorrhage

Deqin Qiu, Guangwei Li, Xiaoyan Hu, Lanlan Wang, Yongfei Dong   +4 more
openalex   +1 more source

Cost-Effectiveness of Cryopreserved vs Liquid-Stored Platelets for Managing Surgical Bleeding.

JAMA Netw Open
Orman Z, Reade MC, Marks DC, Howe BD, Bailey M, Carrandi A, McQuilten ZK, Higgins AM.   +7 more
europepmc   +1 more source

Lipopolysaccharide Potentiates Platelet Aggregation in Association with Apoptosis Through a Novel TLR4-Bax/Bcl-2-Mitochondrial Dysfunction Axis in Humans. [PDF]

Biomolecules
Chen CC, Hsia CW, Huang WC, Chang CC, Darmanto AG, Sheu JR.   +5 more
europepmc   +1 more source

Three‐Year Follow‐Up of Neoadjuvant Tislelizumab with Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Adenocarcinoma: Revealing Cancer‐Associated Fibroblast Heterogeneity Corresponding to PD‐1 Blockade Efficacy

Advanced Science, EarlyView.
Heterogeneous cancer‐associated fibroblasts orchestrate dual immune microenvironments in LAGC. Abstract The potential for immunotherapy in patients with locally advanced gastric cancer (LAGC) is recently confirmed. To report the 3‐year follow‐up data are aimed from a novel clinical trial. This is a prospective single‐arm phase II trial.
Yao Lin, Xiong Sun, Chengguo Li, Ming Yang, Ke Wu, Ke Liu, Anshu Li, Xiaoming Shuai, Kailin Cai, Zheng Wang, Guobin Wang, Peng Zhang, Jianfeng Shen, Kaixiong Tao, Yuping Yin   +14 more
wiley   +1 more source