Results 121 to 130 of about 50,540 (257)
Precision Medical Sciences, EarlyView.Predictive multiomics artificial intelligence (AI) identifies risk but does not indicate which intervention will change a patient's outcome; causal AI, anchored in biological mechanism, bridges this gap to enable individualized treatment decisions.
Gedion Mengistu Dejen
wiley +1 more source
Phytotherapy Research, EarlyView.Functional dyspepsia involves duodenal barrier dysfunction, low‐grade immune activation and altered neuroimmune signalling. Various plant‐derived bioactives may modulate PPAR signalling, reduce inflammatory and oxidative stress, and support epithelial, immune, metabolic, and sensory homeostasis.
Irene Palenca +5 more
wiley +1 more source
Gut microbiota dysbiosis in the inflammatory pathogenesis of diabetic retinopathy
VIEW, EarlyView.This graphical abstract illustrates how gut dysbiosis drives diabetic retinopathy through the gut‐retina axis, a process unfolding in three interconnected stages. First, in the gut, a decrease in beneficial bacteria and an increase in pro‐inflammatory taxa compromise the intestinal barrier, causing a “leaky gut” that allows LPS to translocate into the ...
Junyan Hu, Jingxiang Zhong
wiley +1 more source
VIEW, EarlyView.Abstract Age‐related macular degeneration (AMD) is a degenerative retinal disorder and a leading cause of global visual impairment, yet effective treatments remain limited. While gastritis is a prevalent clinical condition among older populations and has been associated with adverse effects on the central nervous system, its potential association with ...
Jingxin Zhou +5 more
wiley +1 more source
The estimations of heterogeneity and horizontal pleiotropy for MR results.
The estimations of heterogeneity and horizontal pleiotropy for MR results.
Nuannuan Cai (18283822) +4 more
core +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objective To explore the causal relationship between obstructive sleep apnea and body fat percentage and body mass index (BMI) in the East Asian population by using bidirectional Mendelian randomization and multivariate Mendelian randomization.
Rui Fan +5 more
wiley +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Background Certain blood components, including blood lipids, coagulation parameters, and homocysteine, have been suggested to correlate with the incidence and prognosis of sudden sensorineural hearing loss (SSNHL). However, the nature of these associations remains controversial.
Feng‐Xin Yang +8 more
wiley +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objective Obstructive sleep apnea (OSA) is associated with neurocognitive impairment, but its causal relationship with personality traits remains poorly understood. This study investigates the association and causality between OSA and personality using both cohort and genetic data.
Jian‐Hong Liao +4 more
wiley +1 more source
Epistasis and pleiotropy-induced variation for plant breeding [PDF]
Epistasis refers to nonallelic interaction between genes that cause bias in estimates of genetic parameters for a phenotype with interactions of two or more genes affecting the same trait.
Ortiz Rios, Rodomiro Octavio
core
, 2018 Horizontal pleiotropy, where one variant has independent effects on multiple traits, is important for our understanding of the genetic architecture of human phenotypes.
Daniel M. Jordan, Ron Do, Marie Verbanck
core +1 more source