Results 131 to 140 of about 37,616 (263)

Oral Health, Periodontitis, and Respiratory Diseases: Biological Pathways

Journal of Periodontal Research, EarlyView.
This narrative review aims to provide a comprehensive update on the potential mechanisms by which poor oral health and periodontitis impact lung health, focusing on pneumonia, COPD, and asthma. ABSTRACT Poor oral hygiene and periodontitis influence lung diseases such as pneumonia, chronic obstructive pulmonary disease (COPD), COVID‐19, and asthma.
Raluca P. Vacaru, Andreea C. Didilescu, Frank A. Scannapieco   +2 more
wiley   +1 more source

Navigating Mendelian Randomization in Sleep Medicine: Challenges, Opportunities, and Best Practices

Nature and Science of Sleep
Ahmed S BaHammam,1,2 Haitham Jahrami3,4 1The University Sleep Disorders Center, Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia; 2King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia ...
BaHammam AS, Jahrami H
doaj  

Bayesian Mendelian randomization reveals a protective effect of later age at first sexual intercourse against erectile dysfunction. [PDF]

Medicine (Baltimore)
Wu J, Hui X, Hui X.
europepmc   +1 more source

Pleiotropy revisited [PDF]

Nature Reviews Genetics, 2010
openaire   +1 more source

Genomic Evidence on Antihypertensive Drug Targets and Oral Disease Outcomes

Journal of Periodontal Research, EarlyView.
Key Findings Drug‐target Mendelian randomization showed little evidence that genetically proxied on‐target pharmacological actions of most antihypertensive drug classes were associated with chronic periodontitis or dental caries. The diazoxide–periodontitis association requires cautious interpretation, given possible residual pleiotropy at KCNJ11 and ...
Aiswarya Puzhakkara Chennas, Ignacio Leiva‐Escobar, Stefan Lars Reckelkamm, Birte Holtfreter, Thomas Kocher, Sebastian‐Edgar Baumeister, Michael Nolde, Zoheir Alayash   +7 more
wiley   +1 more source

Genetically Predicted Use of Common Analgesics and Risk of Chronic Obstructive Pulmonary Disease: A Bidirectional Mendelian Randomization Study. [PDF]

Int J Chron Obstruct Pulmon Dis
Chen G, You W.
europepmc   +1 more source

Phenotype Refinement Influences GWAS‐Implicated Variant Effect Sizes for Insomnia

Journal of Sleep Research, EarlyView.
ABSTRACT How phenotypes are measured, especially when relying on subjective reports, is an impediment to the utility of genome‐wide association studies (GWAS). This is a common problem in GWAS for sleep traits, as many sleep disturbances appear subjectively similar despite having distinct underlying pathophysiology.
Amber J. Zimmerman, Patrick Z. Liu, Brendan T. Keenan, Thomas G. Brooks, Struan F. A. Grant, Philip R. Gehrman, Ron C. Anafi, Allan I. Pack   +7 more
wiley   +1 more source

Evolutionary perspectives on endometrial cancer: antagonistic pleiotropy. [PDF]

Mol Cell Oncol
Kobayashi H.
europepmc   +1 more source

Small‐scale adaptation to geothermal soil heating in a perennial herb revealed by combining crosses and transplantations

New Phytologist, EarlyView.
Path diagrams showing the results of piecewise structural equation models examining how fitness (total number of seeds in flowering individuals) of Cerastium fontanum depended on temperature at planting site, temperature difference, mating type, and flowering time (FFD, first flowering date) in each of the two study years.
Alicia Valdés, Vigdís F. Helmutsdóttir, Bryndís Marteinsdóttir, Johan Ehrlén   +3 more
wiley   +1 more source

Maternal smoking during pregnancy, other reproductive factors, and neonatal jaundice: A two-sample Mendelian randomization study. [PDF]

Tob Induc Dis
Geng W, Feng D, Qian J.
europepmc   +1 more source