Results 151 to 160 of about 50,540 (257)

Polygenic Risk Modelling in Periodontitis: Insights From a Feasibility Study of 4243 European Cases and Current Limitations

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Background and Aim Genetic susceptibility plays a particularly important role in early‐onset (EO) and severe periodontitis (PD). The genetic risk remains largely unexplained because of limited sample sizes and heterogeneous phenotypes in genome‐wide association studies (GWAS).
Gesa M. Richter, O. Mercy Akinloye, M. Kamal Nasr, Birte Holtfreter, Alicia de Coo, Silvia Diz De Almeida, Bruno G. Loos, Søren Jepsen, Henrik Dommisch, Corinna Bruckmann, Ines Kapferer‐Seebacher, PerioGEN Cohort Group, Georg Homuth, Thomas Kocher, Henry Völzke, Klaus Berger, Matthias Laudes, Wolfgang Lieb, Nathalie van der Velde, Natasja van Schoor, Lisette de Groot, Juan Blanco, Angel Carracedo, Raquel Cruz, Astrid Dempfle, Alexander Teumer, Arne S. Schaefer, Sandra Freitag‐Wolf   +27 more
wiley   +1 more source

Puberty timing and cognitive functioning: insights from the Adolescent Brain Cognitive Development (ABCD) study and Mendelian randomization

Journal of Child Psychology and Psychiatry, EarlyView.
Background Early puberty timing is linked to altered neurodevelopment and adverse mental health outcomes, yet its relationship with cognitive functioning remains unclear. We examined the effects of puberty timing across multiple cognitive domains.
Lars Dinkelbach, Bianca Serio, Sofie Valk, Franka Edith Weisner, Luise Margaretha Bläschke, Triinu Peters, Anke Hinney, Börge Schmidt, Raphael Hirtz   +8 more
wiley   +1 more source

Signatures of selection in pleiotropic genes involved in insect neuronal and immune systems. [PDF]

G3 (Bethesda)
Senthilkumar S, Martin RA, Tate AT.
europepmc   +1 more source

Elevated Blood Pressure Is Causally Associated With Larger Subcortical Gray Matter Structure Through Perivascular Clearance Routes

Journal of Evidence-Based Medicine, EarlyView.
ABSTRACT Background This study aimed to investigate the association between elevated blood pressure (BP) and subcortical gray matter structures, and to elucidate the causality and underlying mechanisms. Methods This study enrolled 1012 participants from a multicenter, population‐based cohort study in China.
Jing Sun, Jing Li, Xiaoshuai Li, Xinyu Zhao, Pengfei Zhao, Zhenghan Yang, Shuohua Chen, Shouling Wu, Ying Hui, Zhenchang Wang, Han Lv   +10 more
wiley   +1 more source

A flexible framework for robust and efficient Mendelian randomization with debiasing. [PDF]

Brief Bioinform
Deng L, He K, Zhang X.
europepmc   +1 more source

Natural variation in GmSOP5 regulates seed oil and protein content during soybean domestication

Journal of Integrative Plant Biology, EarlyView.
The domestication‐related gene Seed Oil and Protein 5 regulates seed oil and protein content without a yield penalty, providing insight into early soybean domestication and identifying a genetic pathway that balances the trade‐off between seed quality and yield in soybean.
Yu Tian, Hao Zhang, Zihao Zheng, Delin Li, Jindong Li, Yingpu Che, Xing Li, Changjiang Li, Huawei Gao, Long Yan, Chaosen Zhao, Jiantao Guan, Jianan Han, Qi Wang, Shiyu Guo, Dong Bai, Jochen C. Reif, Ying‐Hui Li, Li‐Juan Qiu   +18 more
wiley   +1 more source

The bidirectional causal relationships of insomnia with eleven cancers: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Li J, Cheng L, Li F, Xu Y.
europepmc   +1 more source

Beyond the Management Gene: Rethinking and Advancing the Genetic Perspective in Management

Journal of Management Studies, EarlyView.
Abstract Genetics has emerged as a promising avenue for explaining differences in management outcomes, attracting attention from leadership, entrepreneurship, and organizational behaviour scholars. Nonetheless, the field has faced scepticism and made only limited progress, stagnating in the pursuit of a so‐called ‘management gene’ (e.g., leadership ...
Ahmed Maged Nofal, Marcus Wolfe
wiley   +1 more source

Genetically predicted associations between inflammatory cytokines and juvenile idiopathic arthritis: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Pang J, Pan L, Liu P, Qin W, Yang J, Feng Y, He S, Yang S.   +7 more
europepmc   +1 more source

Genome‐wide association study of morphometric and metabolic characteristics in European populations of the sugar kelp Saccharina latissima

Journal of Phycology, EarlyView.
Abstract The sugar kelp Saccharina latissima is a promising candidate for sustainable aquaculture in the North Atlantic and Northeast Pacific, but genetic improvement has been hindered by a limited understanding of the genetic basis of economically important traits.
Stéphane Mauger, Komlan Avia, Lucie Jaugeon, Paolo Ruggeri, Zofia Nehr, Ousseini Issaka Salia, Jérôme Coudret, Emilie Gouhier, Aurélien Baud, Stéphane Loisel, Antoine Fort, Ronan Sulpice, Christophe Destombe, Philippe Potin, J. Mark Cock, Myriam Valero   +15 more
wiley   +1 more source