Results 141 to 150 of about 37,616 (263)

Phenotypic plasticity is broadly adaptive across an elevation gradient in the Cutleaf Monkeyflower

New Phytologist, EarlyView.
Leaf shape plasticity expression is variable in Mimulus laciniatus. Summary Phenotypic plasticity is a key mechanism by which organisms cope with environmental heterogeneity, but its evolutionary consequences depend on how plastic responses align with the broader adaptive landscape.
Jill M. Love, Kathleen G. Ferris
wiley   +1 more source

Early Birds and Thyroid Cancer: Unveiling the Link Between Morningness and Thyroid Cancer Risk Through Mendelian Randomization. [PDF]

Brain Behav
Li H, Zeng C, Han X.
europepmc   +1 more source

The roads most traveled: genetic convergence in plant repeated evolution

New Phytologist, EarlyView.
Observation of a genotype–phenotype association in a focal lineage (magnifying lens) provides a starting point for predicting homolog reuse during repeated trait evolution. This review suggests that the likelihood that mutations in homologous genes contribute to similar phenotypes in other lineages depends on both mutational effect stability (MES) and ...
James W. Satterlee
wiley   +1 more source

Pleiotropy and disease interactors: the dual nature of genes linking ageing and ageing-related diseases. [PDF]

Biogerontology
Vega Magdaleno GD, de Magalhães JP.
europepmc   +1 more source

The Causal Role of Adiposity in Mental Illness: A Systematic Review and Meta‐Analysis of Mendelian Randomization Studies

Obesity Reviews, EarlyView.
ABSTRACT Objective This study aimed to examine the causal effect of adiposity on mental illnesses by summarizing and assessing evidence from Mendelian randomization (MR) studies. Method Searches were conducted on Embase, Medline, and Web of Science from database inception to September 22nd, 2025.
Min Gao, Paul J. Doody, Dimitrios A. Koutoukidis, Yebo Yu, Paul Aveyard, Richard Stevens, Padraig C. Dixon   +6 more
wiley   +1 more source

Causal Effects of Type 2 Diabetes Mellitus on Chronic Periodontitis and the Mediating Role of Oxidative Stress: Evidence From Mendelian Randomization and Mediation Analysis

Oral Diseases, EarlyView.
ABSTRACT Background Type 2 diabetes mellitus (T2DM) is associated with an increased risk of chronic periodontitis, but genetic evidence and oxidative stress‐related pathways remain unclear. Objective This study assessed the genetically inferred association between T2DM and chronic periodontitis, evaluated oxidative stress biomarkers as potential ...
Mengjie Kong, James Kit Hon Tsoi, Kang Li, Cynthia Kar Yung Yiu   +3 more
wiley   +1 more source

A Comprehensive Mendelian Randomization Study of Bidirectional Causal Relationships Between Pain and Mental Disorders [Letter]. [PDF]

J Pain Res
Han J, Ye Y, Mao Y, Lou L.
europepmc   +1 more source

Natural Variation in GmSL20 Improves Seed Size and Quality in Soybean

Plant Biotechnology Journal, EarlyView.
ABSTRACT Seed size plays an important role in determining crop yield, yet the genetic mechanisms underlying the regulation of this agronomic trait remain incompletely understood in soybean. Here, we perform a genome‐wide association study mapping with seed length variations and identify a major quantitative trait locus (QTL) on chromosome 20, named ...
Yuechuan Luo, Zongbiao Duan, Juxu Li, Zhou Zhu, Tong Wu, Dan Li, Yangping Liu, Liangwei Xu, Hao Wen, Yanting Shen, Shulin Liu, Qingtian Li, Zhixi Tian   +12 more
wiley   +1 more source

LEPR Contributes to Lung Squamous Cell Carcinoma: Insights From Mendelian Randomization and Experimental Studies. [PDF]

Cancer Inform
Hu W, Wu G, Lin Y, Li S, Lin Z, Chen Y, Cheng Z, Zeng J, Yang Z, Wang Y.   +9 more
europepmc   +1 more source

Decoding Causality in Periodontal Medicine: Background Factors and Other Sources of Uncertainty

Journal of Periodontal Research, EarlyView.
Philippe Bouchard
wiley   +1 more source