Results 141 to 150 of about 65,328 (279)

Multivariate maternal effects across the internalizing–externalizing spectrum in childhood: results from the Norwegian mother, father, and child cohort study

Journal of Child Psychology and Psychiatry, EarlyView.
Background From a functionalist perspective, parenting behaviors have adaptive functions and are partly expressions of genetic variation. Maternal genes that have effects on children are often referred to as indirect maternal genetic effects. Indirect genetic effects provide a means for measuring the role of parenting without the need for specifying ...
Espen Moen Eilertsen, Nikolai Haahjem Eftedal, Rosa Cheesman, Ziada Ayorech, Joakim Coleman Ebeltoft, Hans Fredrik Sunde, Anneli Desiré Tandberg, Fartein Ask Torvik, Eivind Ystrom   +8 more
wiley   +1 more source

Causal effects of lifestyle and socioeconomic factors on diabetes and its complications and comorbidities: A Mendelian randomization study

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims Diabetes poses a growing global health burden. This study investigated the causal effects of lifestyle and socioeconomic factors on diabetes risk and related complications and comorbidities. Materials and Methods We applied two‐sample univariable and multivariable Mendelian randomization to assess the causal impact of 26 lifestyle and ...
Qian Yu, Zhaowei Kong, Qingde Shi, Chak Kwong Cheng, Jia Zhang, Jinlei Nie   +5 more
wiley   +1 more source

Integrated phenotypes:understanding trait covariation in plants and animals [PDF]

, 2014
Armbruster, Scott, Bolstad, Geir H., Hansen, Thomas F., Pelabon, Christophe   +3 more
core   +1 more source

Pleiotropy revisited [PDF]

Nature Reviews Genetics, 2010
openaire   +1 more source

A Principled Framework for Mendelian Randomization in Oral Health Research

Journal of Periodontal Research, EarlyView.
This methodological article provides a clear and accessible overview of Mendelian randomization for oral health researchers, emphasizing the core assumptions needed for credible causal inference. Focusing on applications in oral health, particularly periodontitis, it highlights both the strengths and limitations of the study design in order to support ...
Nasir Z. Bashir, Mario Romandini, Moritz Kebschull, Konstantinos K. Tsilidis, Dominique S. Michaud, Stephen Burgess   +5 more
wiley   +1 more source

This I believe: Gaining new insights through integrating ‘old’ data

Frontiers in Genetics, 2012
Ruth J.F. Loos, Eric E Schadt
doaj   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Editorial: Statistical Methods, Computing and Resources for Genome-Wide Association Studies

Frontiers in Genetics, 2021
Hailan Liu, Lide Han, Guolian Kang, Min Zhang, Riyan Cheng   +4 more
doaj   +1 more source