Navigating Mendelian Randomization in Sleep Medicine: Challenges, Opportunities, and Best Practices
Ahmed S BaHammam,1,2 Haitham Jahrami3,4 1The University Sleep Disorders Center, Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia; 2King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia ...
BaHammam AS, Jahrami H
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Causal Effects of Diet on Atopic Dermatitis: A Mendelian Randomization Study Implicating Lipid Pathways and Clinical Implications. [PDF]
Wen X +6 more
europepmc +1 more source
Abstract Grain characteristics are the cumulative product of growth and development throughout the growing season. In barley (Hordeum vulgare), these traits determine the grain's value for malting purposes. The ability to accurately predict the genetic merit for malting quality is of great interest for barley breeding programs. Same‐season selection on
Amelia Loeb +10 more
wiley +1 more source
Abstract Biological processes involve complex hierarchies where composite traits result from multiple component traits. However, holistically understanding of how sets of component traits interact to underpin genotype‐to‐phenotype relationships is generally lacking.
John G. Hodge, Andrew D. B. Leakey
wiley +1 more source
Genetic predisposition to smoking and the risk of Carpal Tunnel Syndrome: a mendelian randomization study. [PDF]
Zeng Q +5 more
europepmc +1 more source
Decoding Causality in Periodontal Medicine: Background Factors and Other Sources of Uncertainty
Journal of Periodontal Research, EarlyView.
Philippe Bouchard
wiley +1 more source
Allele‐informed QTL‐seq identifies Hd18 as a minor modifier of heading date in elite rice cultivars
Abstract Fine‐tuning heading date is critical for optimizing yield, grain quality, and local adaptation in rice (Oryza sativa L.). QTL‐seq (where QTL is quantitative trait locus), which integrates bulked segregant analysis with whole‐genome resequencing, provides a rapid and cost‐effective approach for identifying QTLs underlying complex traits ...
Hayeong Lee +5 more
wiley +1 more source
A Retrospective Analysis of Human Angiotensin II Receptor Blockers (ARB) Pharmacokinetics, Dosages and C<sub>max</sub> Values for the Experimental Modelling of Pleiotropic and Supratherapeutic Activities. [PDF]
Evans A, Bernatchez P.
europepmc +1 more source
Genetic control of wheat flour end‐use quality and rheology by genome‐wide association studies
Abstract Improving end‐use quality in bread wheat (Triticum aestivum) requires dissecting the genetic basis of complex processing traits and deploying robust prediction pipelines in breeding. We performed genome‐wide association studies (GWASs) using 1767 high‐quality single‐nucleotide polymorphisms generated by genotyping‐by‐sequencing in a diverse ...
Juan Menor de Gaspar +10 more
wiley +1 more source
Pleiotropy and Facilitation of Local Adaptation in the Silverleaf Sunflower Helianthus argophyllus. [PDF]
Okinedo UE, Moyers BT.
europepmc +1 more source

