Results 161 to 170 of about 37,616 (263)

Causal associations between antibody-mediated immune responses to infectious agents and cardiovascular inflammatory diseases: A Mendelian randomization study based on UK Biobank and FinnGen. [PDF]

Hum Vaccin Immunother
Huang Q, Pan W, Sun S, Chen W, Lin J.
europepmc   +1 more source

Genomic Innovations in High‐Oil Soybean Breeding: Overcoming Yield Barriers and Climate Resilience Challenges

Legume Science, Volume 8, Issue 3, September 2026.
ABSTRACT Soybean (Glycine max L.) is the world's most important oilseed crop, supplying 25% of world‘s edible oil and 66% of feed protein. This review address genomic innovations to overcome yield constraints and climate vulnerability (especially drought stress) in high‐oil soybean breeding.
Mujeeb Ur Rehman, Muhammad Azam, Muhammad Ahsan, Azhar Iqbal, Lili Yu, Jhon Larzabal, Juan E. Rosas, Li‐Juan Qiu   +7 more
wiley   +1 more source

Antagonistic pleiotropy in disease tolerance: Foxo1-Trim63 axis as double-edged sword in age-dependent sepsis. [PDF]

Signal Transduct Target Ther
Chae U, Kim JM, Park YH.
europepmc   +1 more source

Genetic analyses of leaf traits in an interspecific Zoysia japonica × Zoysia matrella F2 population

The Plant Genome, Volume 19, Issue 3, September 2026.
Abstract Zoysiagrass (Zoysia spp.) is an important warm‐season turfgrass cultivated across tropical, subtropical, and temperate regions of the world. The genus is characterized by the presence of salt‐secreting glands on the adaxial leaf surface, which contribute to its high salt tolerance.
Shreena Pradhan, Thomas H. Pendergast IV, John J. Spiekerman, John H. Lagergren, Daniel A. Jacobson, Katrien M. Devos   +5 more
wiley   +1 more source

Causal effect of urinary sodium-to-creatinine ratio on gastrointestinal diseases: A two-sample Mendelian randomization study. [PDF]

Medicine (Baltimore)
Jiang Y, Zhang Z, Ding Y, Xu S, Chen R, Zheng Z, Bao M, He B, Li S.   +8 more
europepmc   +1 more source

Association Between Socioeconomic Status and Atrial Fibrillation: A Two‐Sample Mendelian Randomization Study

Annals of Noninvasive Electrocardiology, Volume 31, Issue 5, September 2026.
Mendelian randomization revealed that lower educational attainment increases atrial fibrillation risk, whereas Townsend deprivation index and household income showed no causal association. These findings highlight education as a key socioeconomic factor influencing atrial fibrillation susceptibility. ABSTRACT Background Lower socioeconomic status (SES),
Shangcai Xie, Xia Zhao, Menghui Mao
wiley   +1 more source

Association Between Hemostatic Profiles and Hypertensive Disorders of Pregnancy: A Multi-Omics Mendelian Randomization Study. [PDF]

Int J Womens Health
Li Y, Long X, Zhang Y, Tu S, Luo W, Wang X, Zeng L, Ye F, Deng X, Zhang Z.   +9 more
europepmc   +1 more source

AMPK‐mediated prevention of vascular dysfunction with metformin: Experimental and population‐based evidence

British Journal of Pharmacology, Volume 183, Issue 17, Page 5389-5406, September 2026.
Angiotensin II induces vascular inflammation, senescence, extracellular matrix (ECM) degradation and endothelial dysfunction, thus impairing SK+/IK+ channel function and reducing endothelial‐dependent hyperpolarisation (EDH). Metformin activates AMPK, increasing SK+/IK+ channel function and restoring vasorelaxation.
Soroush Mohammadi Jouabadi, Annika A. Jüttner, Annique Claringbould, Rene de Vries, Ingrid M. Garrelds, Usha Musterd‐Bhaggoe, Bruno H. Stricker, Maryam Kavousi, A. H. Jan Danser, Fariba Ahmadizar, Anton J. M. Roks   +10 more
wiley   +1 more source

Methods for Prioritizing Causal Genes in Molecular Studies of Human Disease: The State of the Art. [PDF]

Genet Epidemiol
Patasova K, Sedaghati-Khayat B, Knevel R, Cordell HJ, Pratt AG.   +4 more
europepmc   +1 more source

De Novo Complex Genomic Rearrangement Spanning 2q31.1 in a Proband With Congenital Malformations: Genotype–Phenotype Correlation and Development of a CGR Detection Pipeline

American Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1832-1841, August 2026.
ABSTRACT The 2q31 region is commonly associated with pathogenic alleles of the HOXD cluster leading to various clinical phenotypes related to skeletal development. We present a proband with tetralogy of Fallot and multiple congenital anomalies. Genomic variant screening including an in‐house CGR detection pipeline pairing genome sequencing (GS ...
Katherine Helle, Jesse D. Bengtsson, Mira Gandhi, Christopher M. Grochowski, Ming Yin Lun, Neha Sudhir, Shalini N. Jhangiani, Fritz J. Sedlazeck, Seema R. Lalani, Neil A. Hanchard, Claudia M. B. Carvalho   +10 more
wiley   +1 more source