Mendelian randomization of plasma lipidome and temporomandibular joint disorders. [PDF]
Medicine (Baltimore)Jiang Y, Yuan H, Cao Y.
europepmc +1 more source
Genetic Susceptibility to Periodontitis
Journal of Periodontal Research, EarlyView.Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
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Inflammatory and Immunological Basis of Periodontal Diseases
Journal of Periodontal Research, EarlyView.The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
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Multivariable Mendelian Randomization With Weak Instruments: A Comparison of Bayesian and Frequentist Methods. [PDF]
Stat MedGrant AJ, Patel A, Burgess S.
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Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases
Journal of Periodontal Research, EarlyView.This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini +3 more
wiley +1 more source
Oral Health, Periodontitis, and Respiratory Diseases: Biological Pathways
Journal of Periodontal Research, EarlyView.This narrative review aims to provide a comprehensive update on the potential mechanisms by which poor oral health and periodontitis impact lung health, focusing on pneumonia, COPD, and asthma. ABSTRACT Poor oral hygiene and periodontitis influence lung diseases such as pneumonia, chronic obstructive pulmonary disease (COPD), COVID‐19, and asthma.
Raluca P. Vacaru +2 more
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Association between ankylosing spondylitis and hearing loss: A Mendelian randomization study. [PDF]
Medicine (Baltimore)Yang Q, Xu J.
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The Oral‐Hepatic Axis: Epidemiological and Mechanistic Links Between Periodontal and Liver Diseases
Journal of Periodontal Research, EarlyView.This review summarizes current epidemiological, clinical and mechanistic evidence linking periodontitis and chronic liver diseases, highlighting the oral‐gut‐liver axis, shared immunometabolic and nutritional pathways and opportunities for integrated preventive and therapeutic strategies.
Sinem Esra Sahingur +3 more
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Mendelian randomization analysis reveals causal links between specific immune cell phenotypes and Parkinson's disease. [PDF]
Clinics (Sao Paulo)Su Y, Cai S, Xu Y, Xu Q, Wang Q, Chen X.
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Journal of Periodontal Research, EarlyView.This systematic review with meta‐analyzes evaluated the relationship between periodontitis, severe periodontitis, edentulism, and inflammatory bowel disease (IBD). While longitudinal studies suggested a modest association mainly with ulcerative colitis, cross‐sectional evidence consistently supported the coexistence of periodontal disease and IBD ...
Mario Aimetti +6 more
wiley +1 more source