Results 41 to 50 of about 52,107 (249)

Exploring the Molecular Basis of Vesicular Stomatitis Virus Pathogenesis in Swine: Insights from Expression Profiling of Primary Macrophages Infected with M51R Mutant Virus

Pathogens, 2023
Vesicular stomatitis virus (VSV) is an emergent virus affecting livestock in the US. Previously, using a recombinant VSV carrying the M51R mutation in the matrix protein (rNJ0612NME6-M51R), we evaluated the pathogenesis of this virus in pigs. Our results
Lauro Velazquez-Salinas, Gisselle N. Medina, Federico Valdez, Selene Zarate, Shannon Collinson, James J. Zhu, Luis L. Rodriguez   +6 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Identification and genetic characterization of a gibberellin 2-oxidase gene that controls tree stature and reproductive growth in plum [PDF]

, 2011
Several dwarf plum genotypes (Prunus salicina L.), due to deficiency of unknown gibberellin (GA) signalling, were identified. A cDNA encoding GA 2-oxidase (PslGA2ox), the major gibberellin catabolic enzyme in plants, was cloned and used to screen the ...
Prasath, D., Jayasankar, Subramanian, Jayasankar, S., El Kayal, Walid, M. Bouzayen, I. El-Sharkawy, El Kayal, W., W. El Kayal, Bouzayen, M., H. Fernández, Fernández González, Elena, El-Sharkawy, I., Bouzayen, Mondher, D. Prasath, Svircev, A. M., A. M. Svircev, Svircev, Antonet M., El-Sharkawy, Islam, Fernandez, H., S. Jayasankar   +19 more
core   +1 more source

Classical Swine Fever Virus Structural Glycoprotein E2 Interacts with Host Protein ACADM during the Virus Infectious Cycle

Viruses, 2023
The E2 glycoprotein is one of the four structural proteins of the classical swine fever virus (CSFV) particle. E2 has been shown to be involved in many virus functions, including adsorption to host cells, virus virulence and interaction with several host
Elizabeth Vuono, Elizabeth Ramirez-Medina, Ediane Silva, Keith Berggren, Ayushi Rai, Nallely Espinoza, Douglas P. Gladue, Manuel V. Borca   +7 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Reconfigurable nanomechanical photonic metamaterials [PDF]

Dataset for N. I. Zheludev and E. Plum, "Reconfigurable nanomechanical photonic metamaterials," Nature Nanotechnology 11, 16 (2016) doi: 10.1038/nnano.2015 ...
Plum, Eric, Zheludev, Nikolai
core   +1 more source

Live-attenuated foot-and-mouth disease virus vaccine engineered by codon deoptimization induces a strong protective immune response in cattle

npj Vaccines
Foot-and-mouth disease (FMD) is a fast-spreading, economically devastating veterinary viral disease. While inactivated vaccines have contributed to FMD control worldwide, recent outbreaks in Europe and Asia highlight the need for new control strategies ...
Sarah E. Attreed, Christina Silva, Monica Rodriguez-Calzada, Ryan D. Heimroth, Michael Oldakowski, Carolina Stenfeldt, Paul Azzinaro, Edward Spinard, Aishwarya Mogulothu, Steffen Mueller, Bruce Taillon, Jonathan Arzt, Elizabeth Rieder, Teresa de los Santos, Fayna Díaz-San Segundo, Gisselle N. Medina   +15 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Brochure: Plum Run Farms, Inc., "Plum Run Family Farms: This Land is Your Land," Undated

, 2007
Textual: Brochure, original; 16” x 10.5” (40.6 cm x 26.7 cm)Undated brochure produced by Plum Run Farms, Inc. entitled "Plum Run Farms." This brochure discusses a development outside of Louisville, Kentucky on interstate 64 known as Plum Run Farms.
Plum Run Farms, Inc.
core   +1 more source