Generation of iPSC lines with SLC16A2:G401R or SLC16A2 knock out
Stem Cell Research, 2023 The X-linked Allan-Herndon-Dudley syndrome (AHDS) is characterized by severely impaired psychomotor development and is caused by mutations in the SLC16A2 gene encoding the thyroid hormone transporter MCT8 (monocarboxylate transporter 8).
Katarzyna Anna Ludwik +7 more
doaj
Canine pluripotent hematopoietic stem cells and CFU-GM express Ia-like antigens as recognized by two different class II-specific monoclonal antibodies [PDF]
, 1987 F Schuening +6 more
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Advanced Science, EarlyView.A critical aspect of chromosomal remodeling in small molecule‐induced multilineage trans‐differentiation(iMT) is elucidated. A dynamic atlas spanning over 35 days profiles terminal trans‐differentiated cells, which reverted to a more youthful state. This study reveals parallels between iMT and other cell fate determination processes, emphasizing an ...
Weigao E +13 more
wiley +1 more source
How germline genes promote malignancy in cancer cells
BioEssays, Volume 45, Issue 1, January 2023., 2023 We hypothesize that activation of a “germline program” promotes oncogenesis. Expression of otherwise germline specific genes may result in pseudomeiotic activity, thereby promoting oncogenesis through genomic instability. Other processes that are differentially regulated in the germline, such as migration and epigenetic – and metabolic plasticity, may ...
Jan Willem Bruggeman +4 more
wiley +1 more source
Derivation of pluripotent stem cells from cultured human primordial germ cells [PDF]
, 1998 Michael J. Shamblott +8 more
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Nanotherapy for Neural Retinal Regeneration
Advanced Science, EarlyView.Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu +11 more
wiley +1 more source
Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair
Advanced Science, EarlyView.This review discusses various types of electrical stimulation sources and materials, delving into the roles and mechanisms of electrical stimulation therapy in plastic surgery for tissue repair. This work broadens the clinical perspective of electrical stimulation, covering diverse repair needs from bone to soft tissues, and provides insights into ...
Kexin Deng +8 more
wiley +1 more source
mRNA and miRNA expression profiles in an ectoderm-biased substate of human pluripotent stem cells
Scientific Reports, 2019 The potential applications of human pluripotent stem cells, embryonic stem (ES) cells, and induced pluripotent stem (iPS) cells in cell therapy and regenerative medicine have been widely studied.
Shuuji Mawaribuchi +3 more
doaj +1 more source
Adult human cytokeratin 19-positive cells reexpress insulin promoter factor 1 in vitro: further evidence for pluripotent pancreatic stem cells in humans. [PDF]
, 2000 Valéry Gmyr +9 more
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The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges
Advanced Science, EarlyView.This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li +3 more
wiley +1 more source