Culture systems for pluripotent stem cells [PDF]
, 2005 Fernando Ulloa‐Montoya +2 more
openalex +1 more source
Microenvironmental Modulation for Therapeutic Efficacy of Extracellular Vesicles
Advanced Science, EarlyView.Recent studies highlighted the heterogeneity of EVs and the influence of microenvironmental signals on their therapeutic efficacy. This review offers a comprehensive overview of strategies and mechanisms to optimize the therapeutic efficacy of EVs through physical, biochemical, and mechanical modulation.
Bilu Xiang +4 more
wiley +1 more source
Molecular and cellular paradigms of multidrug resistance in cancer
Cancer Reports, Volume 5, Issue 12, December 2022., 2022 Abstract Background The acquisition of resistance to chemotherapy is a major hurdle in the successful application of cancer therapy. Several anticancer approaches, including chemotherapies, radiotherapy, surgery and targeted therapies are being employed for the treatment of cancer.
Foram U. Vaidya +6 more
wiley +1 more source
Isolation of pluripotent embryonic stem cells from reprogrammed adult mouse somatic cell nuclei
, 2000 Megan Munsie +5 more
openalex +1 more source
Variable Reprogramming of the Pluripotent Stem Cell Marker Oct4 in Mouse Clones: Distinct Developmental Potentials in Different Culture Environments [PDF]
, 2005 Michele Boiani +5 more
openalex +1 more source
CeiTEA: Adaptive Hierarchy of Single Cells with Topological Entropy
Advanced Science, EarlyView.CeiTEA, a novel hierarchical clustering algorithm based on topological entropy, effectively captures complex structures underlying data. By constructing an adaptive multi‐nary partition tree, CeiTEA reveals hierarchical structures and local diversifications, outperforming existing methods in clustering accuracy and consistency and providing the ...
Bowen Tan +3 more
wiley +1 more source
Role of eIF4A1 in triple‐negative breast cancer stem‐like cell‐mediated drug resistance
Cancer Reports, Volume 5, Issue 12, December 2022., 2022 Abstract In cap‐dependent translation, the eukaryotic translation initiation factor 4A (eIF4A1) is an mRNA helicase is involved in unwinding of the secondary structure, such as the stem‐loops, at the 5′‐leader regions of the key oncogenic mRNAs. This facilitates ribosomal scanning and translation of the oncogenic mRNAs.
Dayanidhi Raman, Amit K. Tiwari
wiley +1 more source
Wiring the senses: Factors that regulate peripheral axon pathfinding in sensory systems
Developmental Dynamics, Volume 252, Issue 1, Page 81-103, January 2023., 2023 Abstract Sensory neurons of the head are the ones that transmit the information about the external world to our brain for its processing. Axons from cranial sensory neurons sense different chemoattractant and chemorepulsive molecules during the journey and in the target tissue to establish the precise innervation with brain neurons and/or receptor ...
Gemma Nomdedeu‐Sancho, Berta Alsina
wiley +1 more source
Lectin binding profiles of SSEA-4 enriched, pluripotent human embryonic stem cell surfaces [PDF]
, 2005 Alison Venable +6 more
openalex +1 more source
Aggregate, EarlyView.Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai +6 more
wiley +1 more source