Results 181 to 190 of about 980,977 (401)

Microglia-containing cerebral organoids derived from induced pluripotent stem cells for the study of neurological diseases [PDF]

, 2023
Yiling Hong, Dong Xu, Lawrence Chang, Chen Xie, Mariann Chang, José S. Aguilar, Jimmy Lin, Juncheng Lin, Qingshun Quinn Li   +8 more
openalex   +1 more source

Induced Pluripotent Stem Cells

JAMA, 2015
Wilson, Kitchener D., Wu, Joseph C.
openaire   +3 more sources

Nanomaterial‐Based Muscle Cell/Neural Tissue Biohybrid Robots: From Actuation to Biomedical Applications

Advanced Robotics Research, EarlyView.
Muscle cell‐based biohybrid robot using nanomaterials for function enhancement and neural function for biomedical applications. Biohybrid robotics, an emerging field combining biological tissues with artificial systems, has made significant progress in developing various biohybrid constructs, including muscle‐cell‐driven biorobots and microbots.
Minkyu Shin, Sangeun Lee, Su Ryon Shin, Jin‐Ha Choi, Jeong‐Woo Choi   +4 more
wiley   +1 more source

Generation of two induced pluripotent stem cell lines from healthy patients of African American ancestry

Stem Cell Research
Stem cells are a resourceful tool for investigating cardiovascular disease in the context of race and gender. Once derived from blood or skin cells, the reprogrammed induced pluripotent stem cells (iPSCs) adopt an embryonic-like pluripotent state ...
McKay Mullen, Ana Kojic, Christina Alamana, Gabriela Canel, Celine Lai, Joshua W. Knowles, Joseph C. Wu   +6 more
doaj   +1 more source

Metabolite signatures of doxorubicin induced toxicity in human induced pluripotent stem cell-derived cardiomyocytes

, 2017
Umesh Chaudhari, James K. Ellis, Vilas Wagh, Harshal Nemade, Jürgen Hescheler, Hector C. Keun, Agapios Sachinidis   +6 more
openalex   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source

Concise Review: Molecular Cytogenetics and Quality Control: Clinical Guardians for Pluripotent Stem Cells [PDF]

, 2018
Leili Rohani, Adiv A. Johnson, Pooyan Naghsh, Derrick E. Rancourt, Henning Ulrich, Heidrun Holland   +5 more
openalex   +1 more source

Long‐Term Effects of Xenotransplantation of Human Enteric Glia in an Immunocompetent Rat Model of Acute Brain Injury

Advanced Science, EarlyView.
Acute brain injuries are characterized by extensive tissue damage, resulting in debilitating deficits in patients. Despite considerable progress, cell‐based approaches have yet to identify an ideal candidate. This long‐term study explores the use of an untested cell source – human enteric glia – and a non‐invasive administration route – intranasal ...
Nina Colitti, Edwige Rice, Franck Desmoulin, Maylis Combeau, Mélissa Parny, Lorenne Robert, Etienne Buscail, Barbara Bournet, Nathalie Vergnolle, Isabelle Raymond‐Letron, Isabelle Loubinoux, Carla Cirillo   +11 more
wiley   +1 more source

Simple and Robust Differentiation of Human Pluripotent Stem Cells toward Chondrocytes by Two Small-Molecule Compounds [PDF]

, 2019
Manabu Kawata, Daisuke Mori, Kosuke Kanke, Hironori Hojo, Shinsuke Ohba, Ung‐il Chung, Fumiko Yano, Hideki Masaki, Makoto Otsu, Hiromitsu Nakauchi, Sakae Tanaka, Taku Saito   +11 more
openalex   +1 more source

Doxycycline Significantly Enhances Induction of Induced Pluripotent Stem Cells to Endoderm by Enhancing Survival Through Protein Kinase B Phosphorylation

, 2021
Caitlin Peaslee, Cristina Esteva‐Font, Tao Su, Antonio Silvestre Muñoz, Caroline C. Duwaerts, Zhe Liu, Sneha A. Rao, Ke Liu, Marisa W. Medina, Julie B. Sneddon, Jacquelyn J. Maher, Aras N. Mattis   +11 more
openalex   +2 more sources