Results 211 to 220 of about 980,977 (401)

How FAIR is metadata for human pluripotent stem cells? [PDF]

Stem Cell Reports
Hu M, Ankeny RA, Santos D, Wells CA.
europepmc   +1 more source

Standardization of human-induced pluripotent stem cells by optimizing culture conditions and monitoring key parameters [PDF]

Takako Yamamoto, Masaki Hosoya, Shin Kawamata   +2 more
openalex   +1 more source

Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions

Nature Protocols, 2012
Xiaojun Lian, Jianhua Zhang, Samira M. Azarin, Kexian Zhu, Laurie B. Hazeltine, Xiaoping Bao, Cheston Hsiao, T. Kamp, Sean P. Palecek   +8 more
semanticscholar   +1 more source

Promoting Autophagy Mitigates Stress‐Induced Remodeling in Patient iPSC‐CMs with the Phospholamban R9C Mutation

Advanced Science, EarlyView.
The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu, Yawei Shen, Robert J. Barndt, Karim Sallam, Ying Tang, Cameron E. Brown, Xiao Li, Stephen Y. Chan, Joseph C. Wu, Qing Liu, Haodi Wu   +10 more
wiley   +1 more source

Long QT Syndrome Modelling with Cardiomyocytes Derived from Human-induced Pluripotent Stem Cells

Arrhythmia & Electrophysiology Review, 2019
Luca Sala, Massimiliano Gnecchi, Peter J Schwartz   +2 more
doaj   +1 more source

A Novel Cell-Penetrating Lipopeptide for DNA Binding, Self-Assembly, and Delivery Into HeLa and Pluripotent Stem Cells. [PDF]

J Pept Sci
de Mello LR, Honda TSB, Castelletto V, Alves PT, Han SW, da Silva ER, Hamley IW.   +6 more
europepmc   +1 more source

Cardiomyocyte differentiation of individual clones murine induced pluripotent stem cells [PDF]

, 2013
Svitlana Malysheva, Galyna BUDASH, NM Bil'ko, J Heschheller   +3 more
openalex   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

Advanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong, Lavonda Li, Lijie Yan, Long Bai, Jiacan Su, Xingcai Zhang   +5 more
wiley   +1 more source

Why are imprints unstable in pluripotent stem cells? [PDF]

Biochem Soc Trans
Arez M, da Rocha ST.
europepmc   +1 more source

Molecular correlates of topiramate and GRIK1 rs2832407 genotype in pluripotent stem cell-derived neural cultures [PDF]

, 2019
Richard Lieberman, Kevin P. Jensen, Kaitlin Clinton, Eric S. Levine, Henry R. Kranzler, Jonathan Covault   +5 more
openalex   +1 more source