Results 221 to 230 of about 959,542 (406)

Recapitulating the human segmentation clock with pluripotent stem cells

Nature, 2020
Mitsuhiro Matsuda, Yoshihiro Yamanaka, Maya Uemura, M. Osawa, M. Saito, Ayako Nagahashi, Megumi Nishio, Long Guo, S. Ikegawa, Satoko Sakurai, Shunsuke Kihara, Thomas L. Maurissen, Michiko Nakamura, Tomoko Matsumoto, H. Yoshitomi, M. Ikeya, N. Kawakami, Takuya Yamamoto, K. Woltjen, Miki Ebisuya, J. Toguchida, C. Alev   +21 more
semanticscholar   +1 more source

From Bench to Bedside: Emerging Paradigms in CAR‐T Cell Therapy for Solid Malignancies

Advanced Science, EarlyView.
This review discusses emerging paradigms in CAR‐T cell therapy for solid tumors, emphasizing strategies to overcome therapeutic barriers through synthetic biology, immune engineering, and combinatorial approaches. It highlights advancements in logic gating, modulation of the immune microenvironment, and innovative cell designs, providing valuable ...
Yang Chen, Ran Ren, Lirong Yan, Yu Zhou, Ruokai Sun, Huicong Song, Hongfei Yan, Yongsheng Li   +7 more
wiley   +1 more source

An additional human chromosome 21 causes suppression of neural fate of pluripotent mouse embryonic stem cells in a teratoma model [PDF]

, 2007
Afua A. Mensah, Claire Mulligan, Jackie Linehan, Sandra Ruf, Aideen O’Doherty, Beata Grygalewicz, Janet Shipley, Juergen Groet, Victor L. J. Tybulewicz, Elizabeth Fisher, Sebastian Brandner, Dean Nižetić   +11 more
openalex   +1 more source

Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions

Nature Protocols, 2012
Xiaojun Lian, Jianhua Zhang, Samira M. Azarin, Kexian Zhu, Laurie B. Hazeltine, Xiaoping Bao, Cheston Hsiao, T. Kamp, Sean P. Palecek   +8 more
semanticscholar   +1 more source

Super‐Resolution Compatible DNA Labeling Technique Reveals Chromatin Mobility and Organization Changes During Differentiation

Advanced Science, EarlyView.
A novel chromatin‐labeling probe is developed to investigate chromatin mobility during differentiation. The silicon rhodamine–conjugated dCTP is efficiently delivered into iPSCs and NSCs using a synthetic transporter. Super‐resolution microscopy and single‐particle tracking show decreased chromatin mobility during differentiation.
Maruthi K. Pabba, Miroslav Kuba, Tomáš Kraus, Kerem Celikay, Janis Meyer, Sunil Kumar Pradhan, Andreas Maiser, Hartmann Harz, Heinrich Leonhardt, Karl Rohr, Michal Hocek, M. Cristina Cardoso   +11 more
wiley   +1 more source

Long QT Syndrome Modelling with Cardiomyocytes Derived from Human-induced Pluripotent Stem Cells

Arrhythmia & Electrophysiology Review, 2019
Luca Sala, Massimiliano Gnecchi, Peter J Schwartz   +2 more
doaj   +1 more source

Current protocols in the generation of pluripotent stem cells: theoretical, methodological and clinical considerations

Stem Cells and Cloning: Advances and Applications, 2009
Brad B Swelstad, Candace L KerrInstitute for Cell Engineering, Department of Obstetrics and Gynecology, Johns Hopkins University, Baltimore, MA, USAAbstract: Pluripotent stem cells have been derived from various embryonic, fetal and adult sources ...
Brad B Swelstad, Candace L Kerr
doaj  

Generation of Induced Pluripotent Stem Cell Lines from Adult Rat Cells [PDF]

, 2008
Jing Liao, Chun Cui, Siye Chen, Jiangtao Ren, Ji‐Jun Chen, Yuan Gao, Hui Li, Nannan Jia, Lü Cheng, Huasheng Xiao, Lei Xiao   +10 more
openalex   +1 more source

Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients

Nature Biotechnology, 2019
T. Deuse, Xiaomeng Hu, A. Gravina, D. Wang, G. Tediashvili, C. De, W. Thayer, A. Wahl, J. Garcia, H. Reichenspurner, Mark M. Davis, L. Lanier, S. Schrepfer   +12 more
semanticscholar   +1 more source

Mitochondrial Transplantation Augments the Reparative Capacity of Macrophages Following Myocardial Injury

Advanced Science, EarlyView.
Mitochondrial transplantation induces macrophage polarization toward an anti‐inflammatory M2 phenotype, enhances their reparative capacities, and facilitates mitochondrial transfer to cardiomyocytes, collectively promoting tissue repair and functional recovery post‐myocardial infarction.
Yuning Zhang, Xiaolei Sun, Yawei Jin, Kanghui Chen, Lu Zhang, Xiong Gao, Mohan Li, Ze Yuan, Jianguo Jia, Aijun Sun, Junbo Ge   +10 more
wiley   +1 more source