Results 241 to 250 of about 980,977 (401)

Leveraging CRISPR activation for rapid assessment of gene editing products in human pluripotent stem cells

open access: gold
Youjun Wu   +6 more
openalex   +2 more sources

Coating-Free Culture Medium for Establishing and Maintaining Human Induced Pluripotent Stem Cells

open access: gold, 2023
Chih-Yao Lin   +9 more
openalex   +1 more source

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

open access: yesAdvanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto   +11 more
wiley   +1 more source

An inducible iFUCCI reporter cell line for tracking cell cycle dynamics in human pluripotent stem cells and their differentiated progeny

open access: gold
Merve Ay   +6 more
openalex   +1 more source

Coincident Fluorescence‐Burst Analysis of Actin Cargo Molecules in Secreted Single Diffusing Extracellular Vesicles From Human Induced Pluripotent Stem Cells

open access: yesAdvanced Science, EarlyView.
This study presents a two‐color FCCS and coincident‐burst analysis platform to quantify actin cargo in dual‐labeled EVs secreted from hiPSCs. The approach tracks secretion dynamics, confirms actin loading, and measures EV size and cargo number, offering insights into cytoskeletal disruption and neuronal differentiation relevant to neurodegenerative ...
Dang Du Nguyen   +4 more
wiley   +1 more source

Chemically Defined, Efficient Megakaryocyte Production from Human Pluripotent Stem Cells. [PDF]

open access: yesCells
Kim JE   +10 more
europepmc   +1 more source

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