Results 251 to 260 of about 962,530 (405)

Distinct cardiogenic preferences of two human embryonic stem cell (hESC) lines are imprinted in their proteomes in the pluripotent state [PDF]

, 2008
Jennifer C. Moore, Ji‐Dong Fu, Yau-Chi Chan, Dawei Lin, Ha Thi Thanh Tran, Hung‐Fat Tse, Ronald A. Li   +6 more
openalex   +1 more source

Induced pluripotent stem cells in disease modelling and drug discovery

Nature reviews genetics, 2019
R. G. Rowe, G. Daley
semanticscholar   +1 more source

H3K27ac Is Essential for Human Naive Pluripotency Modulated by m6A‐Driven EP300 Expression

Advanced Science, EarlyView.
An et al. reveal H3K27ac elevation is essential for establishing and maintaining human naive pluripotency; its inhibition disrupts this state while enhancement promotes it. METTL3‐mediated m6A modification indirectly controls H3K27ac by suppressing EP300 expression. Reduced EP300 lowers H3K27ac, impeding naive pluripotency.
Chenrui An, Ke Zhong, Xiangjin Kang, Yingying Zhang, Yudan Shang, Hao Liu, Yushan Ji, Jinbei Zeng, Jiajin Lin, Long Jin, Zelong Lin, Yang Yu, Xuetao Shi, Yong Fan   +13 more
wiley   +1 more source

Specific induction of right ventricular-like cardiomyocytes from human pluripotent stem cells. [PDF]

Stem Cell Res Ther
Saito Y, Nakamura K, Katanosaka Y, Iida T, Kusumoto D, Sato R, Adachi R, Shimizu S, Kurokawa J, Akagi S, Yoshida M, Miyoshi T, Morita H, Naruse K, Nishida M, Udono H, Zhang J, Yuasa S, Kamp TJ, Ito H.   +19 more
europepmc   +1 more source

Stability and Hopf bifurcation in a mathematical model of pluripotent stem cell dynamics

, 2005
Mostafa Adimy, Fabien Crauste, Shigui Ruan   +2 more
openalex   +2 more sources

Induced Pluripotent Stem Cells and Human Disease [PDF]

, 2008
Alan Colman
openalex   +1 more source

BHLHE40 Cooperates with GATA2/3 to Control Human Syncytiotrophoblast Lineage Differentiation

Advanced Science, EarlyView.
BHLHE40 interacts directly with GATA2 and GATA3 and co‐occupies genomic loci critical for STB differentiation and function. BHLHE40 also affects GATA2/3 binding at enhancer and promoter regions. Moreover, BHLHE40 is potentially involved in genome‐wide remodeling of H3K4me3 and H3K27ac chromatin landscapes through GATA2/3 recruitment, activating ...
Lijin Peng, Weijie Zhao, Chunfang Xu, Yue Li, Jiani Guo, Taotao Zhou, Philip Chiu, Huimei Wu, Qingyu Wu, Yanxing Wei, Shaorong Gao, Meirong Du   +11 more
wiley   +1 more source

Generation of equine induced pluripotent stem cells from cells of embryonic, perinatal and adult tissues. [PDF]

Stem Cell Res Ther
Barrachina L, Ivanovska A, Eslami Arshaghi T, O'Brien A, Cequier A, Murphy M, Hollinshead F, Rodellar C, Barry F.   +8 more
europepmc   +1 more source

Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells

Nature, 2011
R. Lister, Mattia Pelizzola, Yasuyuki S. Kida, R. D. Hawkins, Joseph R. Nery, G. Hon, Jessica Antosiewicz-Bourget, Jessica Antosiewicz-Bourget, Ronan C. O’Malley, R. Castanon, Sarit A. Klugman, M. Downes, R. Yu, R. Stewart, R. Stewart, B. Ren, Bing-Jie Ren, J. Thomson, R. Evans, J. Ecker   +19 more
semanticscholar   +1 more source

Mitochondria‐Localized Nestin Protects Mesenchymal Stem Cells from Senescence by Maintaining Cristae Structure and Function

Advanced Science, EarlyView.
Nestin localizes to the mitochondrial IMS through its MTS and the TOM20 import machinery. Within the mitochondria, Nestin interacts with Mic60 via its C‐terminal Tail3 domain. Loss of mitochondrial Nestin disrupts cristae architecture, leading to mitochondrial swelling, bioenergetic dysfunction, and ultimately the senescence of hMSCs.
Hainan Chen, Jinsi Chen, Li Huang, Xingqiang Lai, Kai Xia, Qiying Lu, Bingbing Xie, Yinong Huang, Yuan Qiu, Tao Wang, Jianqi Feng, Yuanjun Guan, Siyao Che, Jiancheng Wang, Andy Peng Xiang   +14 more
wiley   +1 more source