Results 261 to 270 of about 962,530 (405)

Induced Pluripotent Stem Cells Generated Without Viral Integration [PDF]

open access: green, 2008
Matthias Stadtfeld   +4 more
openalex   +1 more source

Peptide Electrostatic Modulation Directs Human Neural Cell Fate

open access: yesAdvanced Science, EarlyView.
This study explores the effect of charge on the bioactivity of peptide‐based supramolecular materials. The design of a peptide library with varying charges that self‐assemble into supramolecular fibers is presented, demonstrating how the surface charge of these fibers, used as artificial extracellular matrices, influences the fate of human neural ...
Laura Perez‐Chirinos   +10 more
wiley   +1 more source

Generation of Induced Pluripotent Stem Cell Lines from Adult Rat Cells [PDF]

open access: bronze, 2008
Jing Liao   +10 more
openalex   +1 more source

Exploration of Novel Biomarkers Through a Precision Medicine Approach Using Multi‐Omics and Brain Organoids in Patients With Atypical Depression and Psychotic Symptoms

open access: yesAdvanced Science, EarlyView.
This study examines major depressive disorder with atypical features and psychotic symptoms through a multi‐omics precision medicine approach. By integrating clinical assessments, WBC scRNA‐seq, plasma proteomics, and brain organoid models, it uncovers immune dysregulation, synaptic protein alterations, and stress‐sensitive neuronal changes.
Insook Ahn   +5 more
wiley   +1 more source

Enhanced efficiency of generating induced pluripotent stem (iPS) cells from human somatic cells by a combination of six transcription factors [PDF]

open access: bronze, 2008
Jing Liao   +14 more
openalex   +1 more source

Autologous Organoid‐T Cell Co‐Culture Platform for Modeling of Immune‐Mediated Drug‐Induced Liver Injury

open access: yesAdvanced Science, EarlyView.
A matrix‐free human liver organoid–T cell co‐culture platform enables modeling of immune‐mediated drug‐induced liver injury (iDILI). Using flucloxacillin and patient‐matched cells, this system recapitulates HLA‐B*57:01–restricted CD8⁺ T cell activation and hepatocyte damage.
Fadoua El Abdellaoui Soussi   +11 more
wiley   +1 more source

Recombinant production of canine vitronectin for optimizing the culture of canine induced pluripotent stem cells. [PDF]

open access: yesRegen Ther
Shishida K   +6 more
europepmc   +1 more source

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