Results 271 to 280 of about 980,977 (401)

A human brain microphysiological system derived from induced pluripotent stem cells to study neurological diseases and toxicity_suppl1

, 2016
David Pamies
openalex   +1 more source

Inferring Gene Regulatory Networks From Single‐Cell RNA Sequencing Data by Dual‐Role Graph Contrastive Learning

Advanced Science, EarlyView.
RegGAIN is a novel and powerful deep learning framework for inferring gene regulatory networks (GRNs) from single‐cell RNA sequencing data. By integrating self‐supervised contrastive learning with dual‐role gene representations, it consistently outperforms existing methods in both accuracy and robustness.
Qiyuan Guan, Jiating Yu, Jieyi Pan, Fan Yuan, Jiadong Ji, Rusong Zhao, Zhi‐Ping Liu, Bingqiang Liu, Ling‐Yun Wu, Duanchen Sun   +9 more
wiley   +1 more source

Robust, scalable and xeno-free protocol for differentiating human induced pluripotent stem cells into functional macrophages. [PDF]

Front Immunol
De Homdedeu M, Escribá R, Rodríguez-González K, Querol S, Fernandez-Sojo J, Alvarez-Palomo B.   +5 more
europepmc   +1 more source

Disease-Specific Induced Pluripotent Stem Cells

Cell, 2008
In-Hyun Park, Natasha Arora, Hongguang Huo, Nimet Maherali, Tim Ahfeldt, A. Shimamura, M. Lensch, Chad A. Cowan, K. Hochedlinger, George Q. Daley   +9 more
semanticscholar   +1 more source

Microgel‐Based Hierarchical Porous Hydrogel Patch with Adhesion and Resilience for Myocardial Infarction

Advanced Science, EarlyView.
This study develops a hierarchically porous hydrogel patch strategy (HPMP), based on gas‐shearing microfluidics and an aqueous two‐phase system to fabricate porous microgels as microgel‐based bioinks. The porous microgels with controllable porous structure exhibit excellent cellular behavior.
Ziyang Liu, Leyan Xuan, Yingying Hou, Ting Xie, Jieting Li, Junjie Cai, Siyu Zhang, Yingling Miao, Ning Hou, Gen He, Maobin Xie, Xiyong Yu, Mingen Xu, Guosheng Tang   +13 more
wiley   +1 more source

Predicting metabolic dysfunction-associated steatotic liver disease risk using patient-derived induced pluripotent stem cells. [PDF]

Stem Cells Transl Med
Qin Y, Chhetri P, Theusch E, Lim G, Teker SS, Kuang YL, Aziziraftar SK, Mehraban MH, Munoz-Howell A, Saxena V, Le Guillou D, Mattis AN, Maher JJ, Medina MW.   +13 more
europepmc   +1 more source

“Time Is Brain” – for Cell Therapies

Advanced Science, EarlyView.
The concept that “time is brain” extends to stem cell therapy for stroke. Evidence across preclinical and clinical studies indicates that delivery timing shapes graft survival, integration, and efficacy by matching the evolving post‐stroke microenvironment.
Hao Yin, Dominikus Brian, Rebecca Z. Weber, Patrick D. Lyden, Ruslan Rust   +4 more
wiley   +1 more source

Impact of differentiation protocols on the functionality of mesenchymal stem cells derived from induced pluripotent stem cells. [PDF]

World J Stem Cells
Ababneh NA, Alwohoush E, AlDiqs R, Ismail MA, Al-Kurdi B, Barham R, Al-Atoom R, Nairat F, Al Hadidi S, Whaibi S, Gharandouq MH, Zalloum S, Al Shboul S, Al-Qaisi T, Abuhammad A, Saleh T, Awidi A.   +16 more
europepmc   +1 more source

Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi005-A) from a Wilson's disease patient harboring a homozygous Pro992Leu mutation in ATP7B gene

, 2020
Liting Wei, Jiwei Zhang, Dingbang Chen, Li Feng, Chao Wu, Rui Wang, Xunhua Li   +6 more
openalex   +1 more source

Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors

Science, 2008
K. Okita, M. Nakagawa, Hong Hyenjong, T. Ichisaka, S. Yamanaka   +4 more
semanticscholar   +1 more source