Results 21 to 30 of about 980,977 (401)
Absence of Rybp Compromises Neural Differentiation of Embryonic Stem Cells
Stem Cells International, 2016 Rybp (Ring1 and Yy1 Binding Protein) is a transcriptional regulator and member of the noncanonical polycomb repressive complex 1 with essential role in early embryonic development.
Gergo Kovacs +2 more
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Improving single-cell cloning workflow for gene editing in human pluripotent stem cells [PDF]
, 2018 The availability of human pluripotent stem cells (hPSCs) and progress in genome engineering technology have altered the way we approach scientific research and drug development screens.
Chen, Yi-Hsien, Pruett-Miller, Shondra M
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Frontiers in Cell and Developmental Biology, 2022 The technique of induced pluripotent stem cells has significant application value in breeding and preserving the genetic integrity of fish species. However, it is still unclear whether the chemically induced pluripotent stem cells can be induced from non-
Wenting Xu +21 more
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Retrotransposons in pluripotent stem cells [PDF]
Cell Regeneration, 2020 AbstractTransposable elements constitute about half of the mammalian genome, and can be divided into two classes: the class I (retrotransposons) and the class II (DNA transposons). A few hundred types of retrotransposons, which are dynamic and stage specific, have been annotated.
Jingwen Wang, Junjiu Huang, Guang Shi
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Human stem cells and articular cartilage regeneration. [PDF]
, 2012 The regeneration of articular cartilage damaged due to trauma and posttraumatic osteoarthritis is an unmet medical need. Current approaches to regeneration and tissue engineering of articular cartilage include the use of chondrocytes, stem cells ...
Inui, Atsuyuki +2 more
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Advanced maturation of human cardiac tissue grown from pluripotent stem cells
Nature, 2018 Cardiac tissues generated from human induced pluripotent stem cells (iPSCs) can serve as platforms for patient-specific studies of physiology and disease1–6.
Kacey Ronaldson-Bouchard +9 more
semanticscholar +1 more source
Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells. [PDF]
, 2016 Urea cycle disorders are incurable enzymopathies that affect nitrogen metabolism and typically lead to hyperammonemia. Arginase deficiency results from a mutation in Arg1, the enzyme regulating the final step of ureagenesis and typically results in ...
Angarita, Stephanie Ak +14 more
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Identification and Characterisation of the Early Differentiating Cells in Neural Differentiation of Human Embryonic Stem Cells [PDF]
, 2012 One of the challenges in studying early differentiation of human embryonic stem cells (hESCs) is being able to discriminate the initial differentiated cells from the original pluripotent stem cells and their committed progenies.
Cui, W +7 more
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Construction of 3D in vitro models by bioprinting human pluripotent stem cells: Challenges and opportunities [PDF]
, 2019 Three-dimensional (3D) printing of biological material, or 3D bioprinting, is a rapidly expanding field with interesting applications in tissue engineering and regenerative medicine. Bioprinters use cells and biocompatible materials as an ink (bioink) to
Rosa, Alessandro, Salaris, Federico
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Mechanisms of Development, 2004 Pluripotent embryonic stem cells are undifferentiated cells capable of proliferation and self-renewal and have the capacity to differentiate into all somatic cell types and the germ line. They provide an in vitro model of early embryonic differentiation and are a useful means for targeted manipulation of the genome.
Petitte, J.N, Liu, G, Yang, Z
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