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Pluripotent stem cells in rabbits.
2021International ...
Afanassieff, Marielle +4 more
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Pluripotency of embryonic stem cells
Cell and Tissue Research, 2007Embryonic stem (ES) cells derived from pre-implantation embryos have the potential to differentiate into any cell type derived from the three germ layers of ectoderm (epidermal tissues and nerves), mesoderm (muscle, bone, blood), and endoderm (liver, pancreas, gastrointestinal tract, lungs), including fetal and adult cells.
Yamanaka, S +7 more
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Adult-Derived Pluripotent Stem Cells
World Neurosurgery, 2014The global incidence of spinal cord injury (SCI) is 15-40 cases per million people, with the socioeconomic and healthcare costs amounting to nearly $10 billion per annum in the USA alone. Despite substantial advances in medical care and surgical technology, many patients with SCI still experience significant long-term neurologic disability.
Stuart D, Faulkner +2 more
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Livestock Induced Pluripotent Stem Cells
Reproduction in Domestic Animals, 2012ContentsChimeric animals generated from livestock‐induced pluripotent stem cells (iPSCs) have opened the door of opportunity to genetically manipulate species for the production of biomedical models, improving traits of agricultural importance and potentially providing a system to test novel iPSC therapies.
Y, Lu, J L, Mumaw, F D, West, S L, Stice
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Science, 2008
The generation of pluripotent stem cells from an individual patient would enable the large-scale production of the cell types affected by that patient's disease.
John T. Dimos +12 more
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The generation of pluripotent stem cells from an individual patient would enable the large-scale production of the cell types affected by that patient's disease.
John T. Dimos +12 more
semanticscholar +1 more source
2014
Embryonic stem cells (ESCs) are pluripotent stem cells that are derived from early embryos. Induced pluripotent stem cells (iPSCs) are somatic cell-derived reprogrammed cells that have equivalent characteristics to ESCs. Disease-specific iPSCs have started to be used for the investigation of and development of the treatment for several diseases.
Tatsunori Sakamoto +3 more
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Embryonic stem cells (ESCs) are pluripotent stem cells that are derived from early embryos. Induced pluripotent stem cells (iPSCs) are somatic cell-derived reprogrammed cells that have equivalent characteristics to ESCs. Disease-specific iPSCs have started to be used for the investigation of and development of the treatment for several diseases.
Tatsunori Sakamoto +3 more
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Characterization of pluripotent stem cells
Nature Protocols, 2013Characterization of pluripotent stem cells is required for the registration of stem cell lines and allows for an impartial and objective comparison of the results obtained when generating multiple lines. It is therefore crucial to establish specific, fast and reliable protocols to detect the hallmarks of pluripotency.
Mercè, Martí +7 more
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Pluripotent Stem Cells for Cell Therapy
2021In an increasingly geriatric population, in which elderly people frequently face chronic diseases and degenerative conditions, cell therapies as part of novel regenerative medicine approaches are of great interest. Even though today's cell therapies mostly rely on adult stem cells like the mesenchymal stem cells or primary somatic cells, pluripotent ...
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Pluripotent Stem Cells in Mice
2012Pluripotent stem cells are able to self-renew and to differentiate into all adult cell types. Many studies report data describing these cells and characterize them in molecular terms. Gene expression data of pluripotent and non-pluripotent cells from mouse were assembled.
Rainer, Schmidt +4 more
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Blastocyst-like structures generated from human pluripotent stem cells
Nature, 2021Leqian Yu +9 more
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