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Pluripotent Stem Cells from Germ Cells
2006To date, stem cells have been derived from three sources of germ cells. These include embryonic germ cells (EGCs), embryonal carcinoma cells (ECCs), and multipotent germ line stem cells (GSCs). EGCs are derived from primordial germ cells that arise in the late embryonic and early fetal period of development.
Candace L, Kerr +2 more
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Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells
Science, 2007Junying Yu +11 more
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Mouse-Induced Pluripotent Stem Cells
2012Pluripotent stem cells belong to a unique population of cells, which can self-renew indefinitely and have the potential to give rise to all cell types in an organism. Generally, pluripotent stem cells include embryonic stem cells (ESCs), embryonic germ cells (EGCs), and embryonal carcinoma cells (ECCs) (Boiani and Scholer 2005).
Hui, Zhang, Ying, Jin
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Generation of germline-competent induced pluripotent stem cells
Nature, 2007K. Okita, T. Ichisaka, S. Yamanaka
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Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
Nature Biotechnology, 2008M. Nakagawa +9 more
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Origins of pluripotent stem cells.
Minerva ginecologica, 2011Different types of pluripotent stem cells can be identified and cultured in vitro. Here an overview is presented of the various pluripotent stem cells types. Embryonal carcinoma (EC) cells that have been cultured in vitro provided the groundwork for future pluripotent cell cultures.
Roelen, B.A.J. +1 more
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Generation of Induced Pluripotent Stem Cells
2014Induced pluripotent stem cells (iPSCs) are generated from somatic cells that have been reprogrammed by the ectopic expression of defined embryonic transcription factors. This technology has provided investigators with a powerful tool for modeling disease and developing treatments for human disorders.
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