Results 41 to 50 of about 998,979 (405)

The alternative 3′ splice site of GPNMB may promote neuronal survival after neonatal hypoxic–ischemic encephalopathy injury

Ibrain, 2022
This study aimed to decipher the effect of glycoprotein nonmetastatic melanoma protein B (GPNMB) on neonatal hypoxic–ischemic encephalopathy (NHIE) and its potential molecular mechanism.
Guo‐Jiao Chen, Shan‐Shan Yan, Jing‐Han Zhang, Ji Zhang, Isaac Bul Deng, Rong He   +5 more
doaj   +1 more source

Controlling the Bureaucracy of the Antipoverty Program [PDF]

, 1966
Rapid progress made in various areas of regenerative medicine in recent years occurred both at the cellular level, with the Nobel prize-winning discovery of reprogramming (generation of induced pluripotent stem (iPS) cells) and also at the biomaterial ...
Abounit, Armstrong, Auernheimer, Bae, Banito, Banito, Bao, Bass, Basu-Roy, Beier, Ben-Porath, Binyamin, Bitarte, Booth, Brand, Cantz, Cao, Case, Chappell, Chen, Chen, Chen, Chiou, Chylicki, Cobaleda, de Cremoux, Denishefsky, Dickinson, Doi, Eberhard, Egler, Eshghi, Esteban, Evans, Fagin, Feinstein, Feng, Feng, Fimia, Fusaki, Galli, Ghavami, Ghavami, Ghavami, Ghavami, Ghule, Girouard, Godar, Gore, Guo, Guo, Gustafsson, Hanada, Hanley, Hanna, Harper, Hauff, Hellebrekers, Hench, Hench, Hench, Hockemeyer, Hoffmeyer, Hong, Hotta, Hu, Huang, Jain, Jangamreddy, Jangamreddy, Jeter, Jia, Jia, Jia, Junttila, Kaji, Kang, Karimi-Busheri, Kawamura, Kharas, Kim, Kim, Kochhar, Kumar, Lafontan, Lee, Lefebvre, Lengerke, Li, Li, Liu, Liu, Maddika, Marchetto, Marion, Matsuoka, Matsuura, Menendez, Menendez, Mikkelsen, Miller, Miura, Mizuno, Moawad, Momcilovic, Mortensen, Nadiminty, Nagata, Nakagawa, Nakagawa, Nakatogawa, Neumann, Okita, Okita, Okita, Oliver, Parry, Patel, Peng, Place, Plews, Prigione, Ravikumar, Reya, Ribatti, Rius, Rotter, Rowland, Rubinsztein, Ruoslahti, Räisänen, Sabisz, Saigusa, Salemi, Sato, Schenke-Layland, Shan, Singh, Singh, Sommer, Sridharan, Stadtfeld, Stolzenburg, Suhr, Suo, Takahashi, Tirino, Tsai, Tsaousi, Uchino, Vafa, van den Berg, van Tuyn, Vazquez, Vessoni, Vierbuchen, Vincent, Viswanathan, Viswanathan, Wang, Warren, Wary, Wernig, West, Wiechec, Wiechec, Wilmut, Woltjen, Wu, Xynos, Yamanaka, Yang, Yoshida, Yoshimori, Yu, Zbinden, Zhang, Zhang, Zhang, Zhang, Zhang, Zhao, Zheng, Zhou, Zreiqat   +184 more
core   +4 more sources

Targeting the cytoskeleton to direct pancreatic differentiation of human pluripotent stem cells

Nature Biotechnology, 2020
Generation of pancreatic β cells from human pluripotent stem cells (hPSCs) holds promise as a cell replacement therapy for diabetes. In this study, we establish a link between the state of the actin cytoskeleton and the expression of pancreatic ...
N. Hogrebe, Punn Augsornworawat, Kristina G. Maxwell, Leonardo Velazco-Cruz, J. Millman   +4 more
semanticscholar   +1 more source

Pluripotent stem cell lines [PDF]

Genes & Development, 2008
The derivation of human embryonic stem cells 10 years ago ignited an explosion of public interest in stem cells, yet this achievement depended on prior decades of research on mouse embryonic carcinoma cells and embryonic stem cells. In turn, the recent derivation of mouse and human induced pluripotent stem cells depended on the prior studies on mouse ...
James A. Thomson, Junying Yu
openaire   +3 more sources

Human Amniocytes Are Receptive to Chemically Induced Reprogramming to Pluripotency [PDF]

, 2017
Restoring pluripotency using chemical compounds alone would be a major step forward in developing clinical-grade pluripotent stem cells, but this has not yet been reported in human cells.
Adjaye, J, Campanella, M, De Coppi, P, Eaton, S, Faccenda, D, Guillot, P V, Hau, K-L, Hawkins, K E, Martin-Trujillo, A, Monk, D, Moschidou, D, Ranzoni, A M, Sanchez-Freire, V, Thrasher, A J, Tommasini, F, Wruck, W   +15 more
core   +3 more sources

Regenerative strategies for kidney engineering [PDF]

, 2016
The kidney is the most important organ for water homeostasis and waste excretion. It performs several important physiological functions for homeostasis: it filters the metabolic waste out of circulation, regulates body fluid balances, and acts as an ...
Garreta, Elena, Izpisúa Belmonte, Juan Carlos, Montserrat, Núria   +2 more
core   +1 more source

Advanced maturation of human cardiac tissue grown from pluripotent stem cells

Nature, 2018
Cardiac tissues generated from human induced pluripotent stem cells (iPSCs) can serve as platforms for patient-specific studies of physiology and disease1–6.
Kacey Ronaldson-Bouchard, Stephen P. Ma, K. Yeager, Timothy Chen, LouJin Song, D. Sirabella, K. Morikawa, Diogo Teles, M. Yazawa, G. Vunjak‐Novakovic   +9 more
semanticscholar   +1 more source

Avian pluripotent stem cells

Mechanisms of Development, 2004
Pluripotent embryonic stem cells are undifferentiated cells capable of proliferation and self-renewal and have the capacity to differentiate into all somatic cell types and the germ line. They provide an in vitro model of early embryonic differentiation and are a useful means for targeted manipulation of the genome.
Z Yang, James N. Petitte, G Liu
openaire   +3 more sources

Induced pluripotent stem cells and cerebral organoids from the critically endangered Sumatran rhinoceros

iScience, 2022
Summary: Less than 80 Sumatran rhinos (SR, Dicerorhinus sumatrensis) are left on earth. Habitat loss and limited breeding possibilities are the greatest threats to the species and lead to a continuous population decline.
Vera Zywitza, Silke Frahm, Norman Krüger, Anja Weise, Frank Göritz, Robert Hermes, Susanne Holtze, Silvia Colleoni, Cesare Galli, Micha Drukker, Thomas B. Hildebrandt, Sebastian Diecke   +11 more
doaj  

Using single-cell entropy to describe the dynamics of reprogramming and differentiation of induced pluripotent stem cells [PDF]

, 2020
Induced pluripotent stem cells (iPSCs) provide a great model to study the process of reprogramming and differentiation of stem cells. Single-cell RNA sequencing (scRNA-seq) enables us to investigate the reprogramming process at single-cell level. Here, we introduce single-cell entropy (scEntropy) as a macroscopic variable to quantify the cellular ...
arxiv   +1 more source