Results 91 to 100 of about 16,822 (237)

Enhanced digestion inhibition and mucus penetration of F127-modified self-nanoemulsions for improved oral delivery

Asian Journal of Pharmaceutical Sciences, 2018
Self-nanoemulsifying systems (SNEs) have excellent ability to improve the solubility of poorly water-soluble drugs (PWSD). However, SNEs are likely to be degraded in gastrointestinal (GIT) when their surface is recognized by lipase/co-lipase enzyme ...
Wenyi Song, Yuting Yang, Miaorong Yu, Quanlei Zhu, Mohammadali Soleimani Damaneh, Haijun Zhong, Yong Gan   +6 more
doaj   +1 more source

A Triple‐Nanoparticle System for Controlled Graphene Nanosheet Stacking: Enabling K/Na‐Ion Battery Anodes with Ultra‐Fast Charging Exceeding Petroleum Vehicle Refueling

Advanced Science, EarlyView.
ABSTRACT Large‐ion (K, Na) battery systems mitigate uneven global lithium distribution, while their ability to attain recharge time shorter than refueling would remove the final barrier for secondary batteries to replace petroleum vehicles. However, their large‐ion chemistry makes ultra‐fast charging an even significant challenge.
Shukai Ding, Le Zhang, Hang Li, Yang Zhang, Guoquan Suo, Bin Han, Dongfeng Sun, Wenqi Zhao, Gaohui Du, Qingmei Su, Bingshe Xu, Zhen Xu, Wei Wang   +12 more
wiley   +1 more source

Preparation and Evaluation of Lipid-Based Liquid Crystalline Formulation of Fenofibrate

Advanced Biomedical Research, 2018
Background: Many drugs have poor water solubility and so the oral delivery of such drugs is usually associated with limitation of low bioavailability and lack of dose proportionality.
Moloud Kazemi, Jaleh Varshosaz, Majid Tabbakhian   +2 more
doaj   +1 more source

Lyophilized wafers comprising carrageenan and pluronic acid for buccal drug delivery using model soluble and insoluble drugs [PDF]

, 2013
Lyophilized muco-adhesive wafers with optimum drug loading for potential buccal delivery have been developed. A freeze-annealing cycle was used to obtain optimized wafers from aqueous gels containing 2% κ-carrageenan (CAR 911), 4% pluronic acid (F127), 4.
Babur Chowdhry, Balji, Bansal, Boateng, Boateng, De Brabander, Dixit, Eliasson, Farnoosh Kianfar, Joshua S. Boateng, Kianfar, Kianfar, Kianfar, Kianfar, Lin, Luppi, Mathias, Matthews, McGinnity, Milan Antonijevic, Narasimhan, Passerini, Pyne, Ritger, Roy, Ruiz, Schneid, Shaikh, Siepmann, Smart, Tsinontides, Wu   +31 more
core   +1 more source

Toward Fast‐Charging Polymer‐Electrolyte Based All‐Solid‐State Li–S Batteries: Insights into Limiting Factors and Perspectives

Advanced Science, EarlyView.
The schematic illustrates the important design strategies for polymer solid electrolyte‐based all‐solid‐state lithium‐sulfur batteries (ASSLSBs), including improved ionic conductivity, reduced polysulfide shuttling, stabilized electrode‐electrolyte interfaces, and lithium dendrite mitigation for developing high power and fast charging ASSLSBs ...
S. Jayasubramaniyan, Mingxu Li, Hyeok‐jin Kwon, Sang Yong Nam, Younki Lee, Hyun Woo Kim   +5 more
wiley   +1 more source

Tuning Pluronic Hydrogel Networks: Effects of Vancomycin Loading on Gelation, Rheological Properties, and Micellar Structures

Gels
Thermoresponsive Pluronic hydrogels offer a promising platform for localised antibiotic delivery. However, how drug loading affects the structural integrity and gelation of these systems remains underexplored.
Michael J. Gaffney, Qi Han, Kate Fox, Nhiem Tran   +3 more
doaj   +1 more source

Smart Microgel Studies. Interaction of Polyether-Modified Poly(Acrylic Acid) Microgels with Anticancer Drugs [PDF]

, 2003
Studies of submillimeter gels composed of covalently cross-linked poly(acrylic acid)-g-poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide) (Pluronic-PAA) networks are reviewed in light of potential applications of the microgels as drug ...
Bromberg, Lev, Hatton, T. Alan
core  

Transdermal evaluation of caffeine in different formulations and excipients [PDF]

, 2013
Background: The stratum corneum(SC) forms adifficultphysical barrier fordrugs to pass through the skin. Several strategieswere developed to overcome this barrier.Optimization of topical drug formulations by selected excipients may facilitate the ...
Boonen, Jente, Burvenich, Christian, De Spiegeleer, Bart, Mehuys, Els, Peremans, Kathelijne, Remon, Jean Paul, Roche, Nathalie, Veryser, Lieselotte   +7 more
core   +2 more sources

Microbial Odorant Detection Guides Drosophila Parasitoids Seeking Hosts in Fermenting Fruits

Advanced Science, EarlyView.
Yeast microbes in fermenting fruits attract both host flies and their parasitoid wasps. Female Leptopilina boulardi detect yeast‐emitted ethyl esters via two olfactory receptors, LbouOR167 and LbouOR136. A conserved residue, Leu159, is critical for binding these compounds, enabling female wasps to locate host‐rich habitats.
Yueqi Lu, Lan Pang, Wenqi Shi, Ting Feng, Zhi Dong, Yifeng Sheng, Sicong Zhou, Longtao Yu, Hao Guo, Ying Wang, Jiani Chen, Jianhua Huang   +11 more
wiley   +1 more source

Synergistic Effect of Retinoic Acid Polymeric Micelles and Prodrug for the Pharmacodynamic Evaluation of Tumor Suppression

Frontiers in Pharmacology, 2019
All-trans retinoic acid (ATRA) is an effective agent that induces differentiation, inhibits cell proliferation, and acts as an anticancer agent. ATRA was successfully conjugated with Pluronic F127 via esterification to enhance its anticancer effects ...
Yan-Hua Zhu, Ning Ye, Xin-Feng Tang, Malik Ihsanullah Khan, Hong-Liang Liu, Ning Shi, Li-Feng Hang   +6 more
doaj   +1 more source