In situ gelling systems based on Pluronic F127/Pluronic F68 formulations for ocular drug delivery [PDF]
International Journal of Pharmaceutics, 2016 This study evaluated the use of Pluronic F127 and Pluronic F68 as excipients for formulating in situ gelling systems for ocular drug delivery. Thermal transitions have been studied in aqueous solutions of Pluronic F127, Pluronic F68 as well as their ...
Khateb, Kosai Al +6 more
core +7 more sources
Antimicrobial effectiveness of silver nanoparticles co-stabilized by the bioactive copolymer pluronic F68 [PDF]
Journal of Nanobiotechnology, 2012 Background Silver nanoparticles (AgNps) have attracted much interest in biomedical engineering, since they have excellent antimicrobial properties. Therefore, AgNps have often been considered for incorporation into medical products for skin pathologies ...
dos Santos Carolina Alves +3 more
doaj +5 more sources
Lung cancer targeting efficiency of Silibinin loaded Poly Caprolactone /Pluronic F68 Inhalable nanoparticles: In vitro and In vivo study [PDF]
PLoS ONE, 2022 Silibinin (SB) is shown to have an anticancer properties. However, its clinical therapeutic effects have been restricted due to its low water solubility and poor absorption after oral administration.
Priya Patel +5 more
doaj +3 more sources
Effect of Hyaluronic Acid and Pluronic-F68 on the Surface Properties of Foam as a Delivery System for Polidocanol in Sclerotherapy [PDF]
Pharmaceutics, 2020 The use of foams to deliver bioactive agents and drugs is increasing in pharmaceutics. One example is the use of foam as a delivery system for polidocanol (POL) in sclerotherapy, with the addition of bioactive compounds to improve the delivery system ...
Teresa del Castillo-Santaella +7 more
doaj +2 more sources
Adjuvant Pluronic F68 Is Compatible with a Plant Root-Colonizing Probiotic, Pseudomonas chlororaphis O6 [PDF]
Agrochemicals, 2023 Plant probiotic bacteria are being increasingly used to maximize both the productivity and quality of field crops. Pseudomonas chlororaphis O6 (PcO6) is a plant root colonizer with probiotic activities.
Amanda R. Streeter +5 more
doaj +3 more sources
Surfactant-Enriched Cross-Linked Scaffold as an Environmental and Manufacturing Feasible Approach to Boost Dissolution of Lipophilic Drugs [PDF]
PharmaceuticsBackground/Objectives: The inherent low aqueous solubility of lipophilic drugs, belonging to Class II based on Biopharmaceutical classification system, negatively impacts their oral bioavailability.
Abdelrahman Y. Sherif +2 more
doaj +2 more sources
Tuning Pluronic Hydrogel Networks: Effects of Vancomycin Loading on Gelation, Rheological Properties, and Micellar Structures [PDF]
GelsThermoresponsive Pluronic hydrogels offer a promising platform for localised antibiotic delivery. However, how drug loading affects the structural integrity and gelation of these systems remains underexplored.
Michael J. Gaffney +3 more
doaj +2 more sources
Characterization of a Novel POx-Based Adhesive Powder for Obliterating Dead Spaces After Surgery [PDF]
BioengineeringSurgical dead spaces are challenging to handle with current preventive methods. Tissue adhesives show promise in obliterating ‘dead spaces’, but the drawbacks of currently available adhesives prevent them from being used for dead space elimination.
Steven E. M. Poos +5 more
doaj +2 more sources
Production of Protease Inhibitor With Penicillium sp. — Optimization of the Medium for Growth in Pellet Form and Cytotoxicity Testing [PDF]
Engineering in Life SciencesPenicillium sp. (IBWF 040‐09) produces a protease inhibitor that can potentially be used against the main protease of human African trypanosomiasis. Since the target substance is formed intracellularly (under nutrient limitation), the fungal pellet is ...
Winda Soerjawinata +6 more
doaj +2 more sources
A Novel Docetaxel-Loaded Poly (ε-Caprolactone)/Pluronic F68 Nanoparticle Overcoming Multidrug Resistance for Breast Cancer Treatment [PDF]
Nanoscale Research Letters, 2009 Multidrug resistance (MDR) in tumor cells is a significant obstacle to the success of chemotherapy in many cancers. The purpose of this research is to test the possibility of docetaxel-loaded poly (ε-caprolactone)/Pluronic F68 (PCL/Pluronic F68 ...
Chen Hongli +11 more
doaj +2 more sources