Results 21 to 30 of about 2,789 (155)

Micelles of Progesterone for Topical Eye Administration: Interspecies and Intertissues Differences in Ex Vivo Ocular Permeability

Pharmaceutics, 2020
Progesterone (PG) may provide protection to the retina during retinitis pigmentosa, but its topical ocular supply is hampered by PG poor aqueous solubility and low ocular bioavailability.
Adrián M. Alambiaga-Caravaca, María Aracely Calatayud-Pascual, Vicent Rodilla, Angel Concheiro, Alicia López-Castellano, Carmen Alvarez-Lorenzo   +5 more
doaj   +1 more source

Production, stabilisation and characterisation of silver nanoparticles coated with bioactive polymers pluronic F68, PVP and PVA. [PDF]

IET Nanobiotechnol, 2017
The increasing and alarming panorama of bacterial infections and associated morbidities that occur during medical and hospital procedures makes the development of technologies that aid in controlling such bacterial infections of utmost importance. Recent studies have shown that formulations with metal nanoparticles exhibit good antibacterial properties
Santos CA, Balcão VM, Chaud MV, Seckler MM, Rai M, Vila MMDC.   +5 more
europepmc   +5 more sources

In situ gelling systems based on Pluronic F127/Pluronic F68 formulations for ocular drug delivery [PDF]

International Journal of Pharmaceutics, 2016
This study evaluated the use of Pluronic F127 and Pluronic F68 as excipients for formulating in situ gelling systems for ocular drug delivery. Thermal transitions have been studied in aqueous solutions of Pluronic F127, Pluronic F68 as well as their binary mixtures using differential scanning calorimetry, rheological measurements, and dynamic light ...
Al-Khateb K, Ozhmukhametova EK, Mussin MN, Seilkhanov SK, Rakhypbekov TK, Lau WM, Khutoryanskiy VV   +6 more
openaire   +3 more sources

Phase transitions of aqueous solutions of Pluronic F68 in the presence of Diclofenac Sodium

International Journal of Pharmaceutics, 2023
In recent years, advancements in bioengineering and materials science have witnessed increasing interest in synthetic polymers capable of fulfilling various applications. Owing to their distinctive properties, Pluronics can be used as nano-drug carriers, to deliver poorly water-soluble drugs, and as model systems to study colloidal science by tuning ...
Di Spirito N. A., Grizzuti N., Casalegno M., Castiglione F., Pasquino R.   +4 more
openaire   +3 more sources

Preparation of poly(NIPAAm)-Pluronic F68 as a thermosensitive surfactant for a controlled drug release. [PDF]

Int J Pharm Investig, 2011
This paper describes the synthesis of thermosensitive surfactants by polymerizing N-isopropylacrylamide (NIPAAm) into the Pluronic F68 surfactant and their application for a controlled drug release. Poly(NIPAAm)-Pluronic surfactants with different lengths of the NIPAAm block were synthesized by activating two hydroxyl groups of poly(ethylene oxide ...
Choi SW, Lee HM, Park TJ, Kim JH.
europepmc   +4 more sources

Triblock Copolymer Pluronic F68 as a Corrosion Inhibitor for Aluminum-air Battery: An Electrochemical and in Silico Study

International Journal of Electrochemical Science, 2019
In Al-air batteries, the self-corrosion of aluminum electrodes is an issue worthy of concern. In this paper, the inhibition performance and anti-corrosion mechanism of a triblock copolymer, namely, Pluronic F68, on Al in 3.5% NaCl electrolyte are ...
Lei Guo, Jianhong Tan, Hong Yang, Youness El Bakri, Sava Kaya, Senlin Leng, Yingchang Yang, Wei Shi   +7 more
doaj   +1 more source

Bibliometric analysis of articles on nanoemulsion and/or in-situ gel for ocular drug delivery system published during the 2011–2021 period [PDF]

Pharmacia, 2022
The bibliometric data were extracted from the Scopus database to investigate the conceptual framework of ocular nanoemulsion and/or in-situ gel drug delivery system using “ocular” AND “nanoemulsion” OR “in-situ gel” keywords. The data were evaluated with
Siti Fatmawati Fatimah, Endang Lukitaningsih, Ronny Martien, Akhmad Kharis Nugroho   +3 more
doaj   +3 more sources

Size-Controllable Prussian Blue Nanoparticles Using Pluronic Series for Improved Antioxidant Activity and Anti-Inflammatory Efficacy

Antioxidants, 2022
Prussian blue (PB) is a metal cluster nanoparticle (NP) of cyanide-bridged iron(II)–iron(III) and exhibits a characteristic blue color. Its peroxidase-, catalase-, and superoxide-dismutase-like activities effectively remove excess reactive oxygen species
Hyeryeon Oh, Jin Sil Lee, Daekyung Sung, Siyoung Yang, Won Il Choi   +4 more
doaj   +1 more source

Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug.

PLoS Neglected Tropical Diseases, 2021
BackgroundHuman African trypanosomiasis (HAT or sleeping sickness) is caused by the parasite Trypanosoma brucei sspp. The disease has two stages, a haemolymphatic stage after the bite of an infected tsetse fly, followed by a central nervous system stage ...
Lisa Sanderson, Marcelo da Silva, Gayathri N Sekhar, Rachel C Brown, Hollie Burrell-Saward, Mehmet Fidanboylu, Bo Liu, Lea Ann Dailey, Cécile A Dreiss, Chris Lorenz, Mark Christie, Shanta J Persaud, Vanessa Yardley, Simon L Croft, Margarita Valero, Sarah A Thomas   +15 more
doaj   +1 more source

Pluronic F-68 and F-127 Based Nanomedicines for Advancing Combination Cancer Therapy

Pharmaceutics, 2023
Pluronics are amphiphilic triblock copolymers composed of two hydrophilic poly (ethylene oxide) (PEO) chains linked via a central hydrophobic polypropylene oxide (PPO).
Nisar Ul Khaliq, Juyeon Lee, Sangwoo Kim, Daekyung Sung, Hyungjun Kim   +4 more
doaj   +1 more source