Synthesis, characterization and anti-cancer activity of Pluronic F68–curcumin conjugate micelles [PDF]
Drug Delivery, 2015 Curcumin (CUR), a nontoxic polyphenol derived from the rhizome of turmeric (Curcuma longa), has been recognized as an anti-cancer and chemo-preventative agent. However, its clinical application for cancer treatment has been greatly limited due to its poor water-solubility and low bioavailability.
Yuee, Cai +6 more
openaire +2 more sources
Pluronic F-68 and F-127 Based Nanomedicines for Advancing Combination Cancer Therapy
Pharmaceutics, 2023 Pluronics are amphiphilic triblock copolymers composed of two hydrophilic poly (ethylene oxide) (PEO) chains linked via a central hydrophobic polypropylene oxide (PPO).
Nisar Ul Khaliq +4 more
doaj +1 more source
Protein microspheres as suitable devices for piroxicam release [PDF]
, 2012 Bovine serum albumin-piroxicam (BSA-piroxicam) and human serum albumin-piroxicam (HSA-piroxicam) microspheres were sonochemically prepared and characterized.
Carvalho, Ana C. +4 more
core +1 more source
Brazilian Archives of Biology and Technology, 2021 Hesperidin is a natural compound which is found in citric fruits and presents antitumor and antimicrobial activities. However, the in vivo efficacy of Hesperidin is reduced due to its low oral bioavailability.
Irineo Kelte Filho +6 more
doaj +1 more source
Solid Dispersions as a Tool for Innovation in the Food Industry: A Path From Pharma to Food. [PDF]
J Food SciABSTRACT Solid dispersion (SD) is a technique used to improve the solubility of poorly water‐soluble compounds by dispersing them in a solid water‐friendly carrier. Current trends indicate that natural‐based alternatives are increasingly replacing synthetic carriers, benefiting the pharmaceutical industry, where they were first adopted, and paving the ...
Rezende SC +3 more
europepmc +2 more sources
Pluronic F-127 hydrogel as a promising scaffold for encapsulation of dental-derived mesenchymal stem cells. [PDF]
, 2015 Dental-derived mesenchymal stem cells (MSCs) provide an advantageous therapeutic option for tissue engineering due to their high accessibility and bioavailability.
Ansari, Sahar +7 more
core +1 more source
Nanostructured Cubosomes in a Thermoresponsive Depot System: An Alternative Approach for the Controlled Delivery of Docetaxel [PDF]
, 2015 The aim of the present study was to develop and evaluate a thermoresponsive depot system comprising of docetaxel-loaded cubosomes. The cubosomes were dispersed within a thermoreversible gelling system for controlled drug delivery. The cubosome dispersion
Dave, Vivek S. +5 more
core +1 more source
New Biopolymer Nanoparticles Improve the Solubility of Lipophilic Megestrol Acetate
Molecules, 2016 As many substances are poorly soluble in water and thus possess decreased bioavailability, creating orally administered forms of these substances is a challenge.
Malwina Lachowicz +5 more
doaj +1 more source
PLoS ONE, 2021 Constraints related to sample preparation are some of the primary obstacles to widespread deployment of molecular diagnostics for rapid detection of trace quantities (≤103 CFU/mL) of food-borne pathogens.
Lena Diaz, Yong Li, Daniel M Jenkins
doaj +1 more source
Improved Poly (D,L-lactide) nanoparticles-based formulation for hair follicle targeting [PDF]
, 2015 Objective Hair follicles are widely recognized as the preferential target and site of accumulation for nanoparticles after topical application. This feature is of particular importance for hair cosmetics, having the potential to refine the treatment of ...
Fernandes, Bruno Pacheco +5 more
core +1 more source