Results 11 to 20 of about 5,618 (207)
Galangin loaded galactosylated pluronic F68 polymeric micelles for liver targeting
Biomedicine & Pharmacotherapy, 2019 Galangin possess wide range of pharmacological activities including antiarthritic, hepatoprotective, anti-inflammatory, antibacterial, and anticancer especially in hepatocellular carcinoma. However, its biological use has been limited owing to its poor aqueous solubility, P-gp efflux and rapid in vivo metabolism by cytochrome enzymes.
Sharvil, Patil +4 more
openaire +4 more sources
Gemcitabine-Vitamin E Prodrug-Loaded Micelles for Pancreatic Cancer Therapy [PDF]
PharmaceuticsPancreatic cancer (PC) is an aggressive cancer subtype presenting unmet clinical challenges. Conventional chemotherapy, which includes antimetabolite gemcitabine (GEM), is seriously undermined by a short half-life, its lack of targeting ability, and ...
Miguel Pereira-Silva +7 more
doaj +2 more sources
Pluronic F68 Micelles as Carriers for an Anti-Inflammatory Drug: A Rheological and Scattering Investigation. [PDF]
LangmuirAge-long ambition of medical scientists has always been advancement in healthcare and therapeutic medicine. Biomedical research indeed claims paramount importance in nanomedicine and drug delivery, and the development of biocompatible storage structures for delivering drugs stands at the heart of emerging scientific works.
Di Spirito NA +5 more
europepmc +4 more sources
Highly Water-Dispersed Natural Fullerenes Coated with Pluronic Polymers as Novel Nanoantioxidants for Enhanced Antioxidant Activity [PDF]
AntioxidantsFullerene is a cosmic material with a buckyball-like structure comprising 60 carbon atoms. It has attracted significant interest because of its outstanding antioxidant, antiviral, and antibacterial properties.
Hyeryeon Oh +8 more
doaj +2 more sources
Inhibition of Angiogenesis and Effect on Inflammatory Bowel Disease of Ginsenoside Rg3-Loaded Thermosensitive Hydrogel [PDF]
PharmaceuticsBackground: Inflammatory bowel disease (IBD), characterized by chronic inflammation of the digestive tract, involves angiogenesis as a key pathogenic mechanism.
Yiqiong Xie +12 more
doaj +2 more sources
The Langmuir Monolayer as a Model Membrane System for Studying the Interactions of Poly(Butyl Cyanoacrylate) Nanoparticles with Phospholipids at the Air/Water Interface [PDF]
MembranesPoly(butyl cyanoacrylate) (PBCA) nanoparticles have numerous applications, including drug and gene delivery, molecular imaging, and cancer therapy. To uncover the molecular mechanisms underlying their interactions with cell membranes, we utilized a ...
Georgi Yordanov +2 more
doaj +2 more sources
Int J Pharm Investig, 2011 This paper describes the synthesis of thermosensitive surfactants by polymerizing N-isopropylacrylamide (NIPAAm) into the Pluronic F68 surfactant and their application for a controlled drug release. Poly(NIPAAm)-Pluronic surfactants with different lengths of the NIPAAm block were synthesized by activating two hydroxyl groups of poly(ethylene oxide ...
Choi SW, Lee HM, Park TJ, Kim JH.
europepmc +4 more sources
AgrochemicalsSurfactants are widely utilized in agriculture as emulsifying, dispersing, anti-foaming, and wetting agents. In these adjuvant roles, the inherent biological activity of the surfactant is secondary to the active ingredients.
Anthony Cartwright +6 more
doaj +2 more sources
Fluids, 2022 Due to the high complexity of some treatments, there is a need to develop drug-delivery systems that can release multiple drugs/bioactive agents at different stages of treatment.
Henrique Carrêlo +4 more
doaj +1 more source
Pharmaceutics, 2021 We previously designed ophthalmic formulations (nTRA) containing tranilast nanoparticles (Tra-NPs) with high uptake into ocular tissues. In this study, we used in situ gel (ISG) bases comprising combinations of pluronic F127 (F127) and methylcellulose ...
Misa Minami +6 more
doaj +1 more source