Results 31 to 40 of about 15,930 (228)
Frontiers in Microbiology, 2016 Chronic inflammatory rheumatic diseases (CIRDs) are immune-mediated pathologies involving joints. To date, TNFα-blocking agents administration is the most promising therapy, although these treatments are associated with an increased Polyomavirus JC ...
Donatella Maria Rodio +11 more
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Iraqi Journal of Hematology, 2021 BACKGROUND: Acute promyelocytic leukemia (APL) is a well-defined subtype of acute myeloic leukemia (AML) and known by t (15;17)(PML-RARA) mutation. About 20%–40% of AML patients indicate FMS-like tyrosine kinase 3 (FLT3) mutations. FLT3 mutations contain
Mehdi Mohammadi Kanesbi +3 more
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Entry with two correlated signals : the case of industrial espionage and its positive competitive effects [PDF]
, 2021 Recent advances in information and communication technologies have increased the incentives for firms to acquire information about rivals. These advances may have major implications for market entry because they make it easier for potential entrants to ...
Barrachina Monfort, Alejandro +2 more
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The role of PML and PML nuclear bodies in FADD-mediated apoptosis [PDF]
, 2014 PML nuclear bodies (NBs) consist of more than 80 constituents and are involved in many cellular processes such as apoptosis, DNA repair, cell cycle, transcriptional regulation and development.
Jensen, Kirsten Ellerup
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Subcellular distribution of nuclear import-defective isoforms of the promyelocytic leukemia protein [PDF]
, 2010 Background The promyelocytic leukemia (PML) protein participates in a number of cellular processes, including transcription regulation, apoptosis, differentiation, virus defense and genome maintenance.
Åsne Jul-Larsen +3 more
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JC polyomavirus infection is strongly controlled by human leucocyte antigen class II variants.
PLoS Pathogens, 2014 JC polyomavirus (JCV) carriers with a compromised immune system, such as in HIV, or subjects on immune-modulating therapies, such as anti VLA-4 therapy may develop progressive multifocal leukoencephalopathy (PML) which is a lytic infection of ...
Emilie Sundqvist +16 more
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NPM and BRG1 Mediate Transcriptional Resistance to Retinoic Acid in Acute Promyelocytic Leukemia
Cell Reports, 2016 Perturbation in the transcriptional control of genes driving differentiation is an established paradigm whereby oncogenic fusion proteins promote leukemia. From a retinoic acid (RA)-sensitive acute promyelocytic leukemia (APL) cell line, we derived an RA-
Jessica N. Nichol +4 more
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The role of PML proteins in adenovirus type 5 infection and the type I interferon response [PDF]
, 2010 Promyelocytic leukaemia (PML) proteins consist of a collection of related isoforms that are the nucleating components of sub-nuclear structures termed PML nuclear bodies (PML NBs). Numerous functions are attributed to PML and PML NBs, including a role
Wright, Jordan
core +2 more sources
Characterization and functional analysis of chicken promyelocytic leukemia protein
Poultry Science: In mammals, promyelocytic leukemia (PML) protein, also named as TRIM19, is the key component of nuclear membrane-less sub structures PML nuclear bodies (PML-NB) or nuclear domains 10 (ND10). PML-NBs are dynamic foci that consist of numerous permanently
Shengnan Wang +8 more
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Journal of Neuroinflammation, 2020 Background Progressive multifocal leukoencephalopathy (PML) caused by JC virus (JCV) is a rare but serious complication of some disease-modifying drugs used to treat multiple sclerosis (MS).
Mitsuru Watanabe +9 more
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