Results 151 to 160 of about 2,913 (168)

Allele-specific PCR method based on pncA and oxyR sequences for distinguishing Mycobacterium bovis from Mycobacterium tuberculosis: intraspecific M. bovis pncA sequence polymorphism.

Journal of clinical microbiology, 1998
An allele-specific amplification method based on two genetic polymorphisms to differentiate Mycobacterium tuberculosis from Mycobacterium bovis was tested. Based on the differences found at position 169 in the pncA genes from M. tuberculosis and M. bovis, a PCR system which was able to differentiate most of the 237 M.
L E, Espinosa de los Monteros, J C, Galán, M, Gutiérrez, S, Samper, J F, García Marín, C, Martín, L, Domínguez, L, de Rafael, F, Baquero, E, Gómez-Mampaso, J, Blázquez   +10 more
openaire   +1 more source

Novel pncA Mutations in Pyrazinamide-Resistant Isolates of Mycobacterium tuberculosis.

Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology
The gene coding for pyrazinamidase (PZase) activity, pncA, in Mycobacterium tuberculosis was recently cloned, and several mutations which correlate with in vitro resistance to pyrazinamide (PZA) have been identified. During the development of a clinical molecular assay for the detection of PZA resistance, two previously unreported mutations in isolates
, Sachais, , Nachamkindagger, , Mills, , Leonard   +3 more
openaire   +1 more source

Characterization of pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis isolates from Korea and analysis of the correlation between the mutations and pyrazinamidase activity

World Journal of Microbiology and Biotechnology, 2014
Youngtae Ro
exaly  

Identification of Enzymatic Catalysis of PncA using 1H-NMR

Journal of the Korean Magnetic Resonance Society, 2017
Bong-Jin Lee
exaly  

Detection of Mycobacterium tuberculosis pncA Mutations by the Nipro Genoscholar PZA-TB II Assay Compared to Conventional Sequencing

Antimicrobial Agents and Chemotherapy, 2018
Sven Hoffner, James Posey, Joshua Havumaki   +2 more
exaly  

Mutations Found in the pncA Gene of Mycobacterium tuberculosis in Clinical Pyrazinamide-resistant Isolates from a Local Region of China

Journal of International Medical Research, 2009
Xian-En Zhang
exaly  

Molecular investigation against the resistant mechanism of PncA mutated pyrazinamide resistance and insight into the role of pH environment for pyrazinamide activation

Journal of Biomolecular Structure and Dynamics, 2020
Ashok Sharma, Gaurava Srivastava, Mahendra Darokar   +2 more
exaly  

Pyrazinamide Susceptibility and pncA Mutation Profiles of Mycobacterium tuberculosis among Multidrug-Resistant Tuberculosis Patients in Bangladesh

Antimicrobial Agents and Chemotherapy, 2017
Arfatur Rahman, Sayera Banu, Shahriar Ahmed   +2 more
exaly  

Non- pncA Gene-Mutated but Pyrazinamide-Resistant Mycobacterium tuberculosis: Why Is That?

Journal of Clinical Microbiology, 2017
Mikael Mansjö, Erik Alm, Jim Werngren   +2 more
exaly  

Detection of Mutations in Mycobacterium tuberculosis pncA Gene by Modified High-Resolution Melting Curve Analysis of PCR Products

Bulletin of Experimental Biology and Medicine, 2019
Filipenko M L, M L Filipenko, Khrapov E A   +2 more
exaly