Results 81 to 90 of about 91,224 (305)

Metabolomic Profiling of Lungs from Mice Reveals the Variability of Metabolites in Pneumocystis Infection and the Metabolic Abnormalities in BAFF-R-Deficient Mice

Journal of Inflammation Research, 2023
Heng-Mo Rong,* Han-Yu-Jie Kang,* Zhao-Hui Tong Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, People’s Republic of China ...
Rong HM, Kang HYJ, Tong ZH
doaj  

Refractory flare-up of severe bronchial asthma controlled with mepolizumab due to Pneumocystis pneumonia: a case report

Allergy, Asthma & Clinical Immunology, 2022
Background Biologics dramatically improve symptoms of severe asthma; however, various exacerbating factors may induce flare-up. Pneumocystis spp. have not been reported as a cause of asthma exacerbation during biologic use, although patients with severe ...
Kazuya Takeda, Toshiyuki Sumi, Yuta Nagahisa, Keigo Matsuura, Motoki Sekikawa, Hiroki Watanabe, Yuichi Yamada, Hirofumi Chiba   +7 more
doaj   +1 more source

Pneumocystis Exacerbates Inflammation and Mucus Hypersecretion in a Murine, Elastase-Induced-COPD Model

Journal of Fungi, 2023
Inflammation and mucus hypersecretion are frequent pathology features of chronic respiratory diseases such as asthma and COPD. Selected bacteria, viruses and fungi may synergize as co-factors in aggravating disease by activating pathways that are able to
Diego A. Rojas, Carolina A. Ponce, Adriel Bustos, Vicente Cortés, Daniela Olivares, Sergio L. Vargas   +5 more
doaj   +1 more source

Pulmonary mycobiome of patients with suspicion of respiratory fungal infection – an exploratory study [PDF]

, 2019
Objective: This pilot study aimed to characterize the pulmonary mycobiome of patients with suspicion of fungal infection of the respiratory tract as well as to identify potentially pathogenic fungi colonizing/infecting their lungs. Methods: A cohort of
Oliveira, Mariana, Pinto, Miguel, Sabino, Raquel, Veríssimo, Cristina   +3 more
core  

The Contribution of Host Cells to Pneumocystis Immunity: An Update

Pathogens, 2019
Pneumocystis is a ubiquitous atypical fungus that is distributed globally. The genus comprises morphologically similar but genetically heterogeneous species that have co-evolved with specific mammalian hosts as obligate intra-pulmonary pathogens.
Patricia Otieno-Odhiambo, Patricia Otieno-Odhiambo, S. Wasserman, J. C. Hoving   +3 more
semanticscholar   +1 more source

What do Pneumocystis organisms tell us about the phylogeography of their hosts? The case of the woodmouse Apodemus sylvaticus in continental Europe and western Mediterranean islands.

PLoS ONE, 2015
Pneumocystis fungi represent a highly diversified biological group with numerous species, which display a strong host-specificity suggesting a long co-speciation process.
Christine Demanche, Manjula Deville, Johan Michaux, Véronique Barriel, Claire Pinçon, Cécile Marie Aliouat-Denis, Muriel Pottier, Christophe Noël, Eric Viscogliosi, El Moukhtar Aliouat, El Moukhtar Aliouat, Eduardo Dei-Cas, Serge Morand, Jacques Guillot   +13 more
doaj   +1 more source

Genetic Polymorphisms of Superoxide Dismutase Locus of Pneumocystis jirovecii in Spanish Population

Frontiers in Public Health, 2019
Objective:Pneumocystis pneumonia remains a major opportunistic infection in immunocompromised patients worldwide. Colonization with Pneumocystis jirovecii has recently gained attention as an important issue for understanding the complete cycle of human ...
Rubén Morilla, Rubén Morilla, Rubén Morilla, Amaia González-Magaña, Amaia González-Magaña, Vicente Friaza, Yaxsier de Armas, Francisco J. Medrano, Francisco J. Medrano, Enrique J. Calderón, Enrique J. Calderón, Carmen de la Horra, Carmen de la Horra   +12 more
doaj   +1 more source

PRIMACENES: novel non-cytotoxic primaquine-ferrocene conjugates with anti-Pneumocystis carinii activity [PDF]

, 2010
Primacenes, novel ferrocene-primaquine conjugates, were synthesized and screened for their antimalarial and anti-pneumocystis activity. Primacenes obtained by coupling primaquine amino acid derivatives to ferrocenoic acid were significantly active ...
Jiri Gut, Joana Matos, Margaret S Collins, Melanie T Cushion, Nuno Vale, Paula Gomes, Philip J Rosenthal, Rui Moreira   +7 more
core   +1 more source

IL-10-producing B cells regulate Th1/Th17-cell immune responses in Pneumocystis pneumonia.

American Journal of Physiology - Lung cellular and Molecular Physiology, 2019
Pneumocystis pneumonia (PCP) is a common opportunistic infectious disease that is prevalent in immunosuppressed hosts. Accumulating evidence shows that B cells play an important role in infectious diseases.
Heng-Mo Rong, Ting Li, Chao Zhang, Dong Wang, Yang Hu, Kan Zhai, Huanzhong Shi, Z. Tong   +7 more
semanticscholar   +1 more source

Utility of BioFire FilmArray Pneumonia Panel Plus in a High‐Risk Cohort: Children Post Allogeneic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary complications due to infection contribute significantly to post‐haematopoietic stem cell transplant (HCT) morbidity and mortality. Standard microbiological investigations, when performed on bronchoalveolar lavage (BAL) fluid, can take days to weeks to confirm a diagnosis.
Hannah Walker, Theresa Cole, Liam Gubbels, Helen Pham, Melanie Neeland, Diane Hanna, Vanessa Clifford, Shivanthan Shanthikumar, Gabrielle M. Haeusler   +8 more
wiley   +1 more source