Results 101 to 110 of about 7,584 (199)

Novel Approaches to the Identification of Streptococcus pneumoniae as the Cause of Community-Acquired Pneumonia [PDF]

, 2017
Current diagnostic tests lack sensitivity for the identification of the bacterial etiology of pneumonia. Attempts during the past 2 decades to improve sensitivity of detection of bacterial constituents in blood by use of antibody-antigen complexes and ...
Albrich, Werner C., Klugman, Keith P., Madhi, Shabir A.   +2 more
core  

Mini-Review: Novel Therapeutic Strategies to Blunt Actions of Pneumolysin in the Lungs [PDF]

, 2013
Rudolf Lucas, István Czikora, Supriya Sridhar, Evgeny Zemskov, Boris Gorshkov, Umapathy Siddaramappa, Aluya Oseghale, Jonathan Lawson, Alexander D. Verin, Ferenc G. Rick, Norman L. Block, Helena Pillich, Maritza J. Romero, Martin Leustik, Andrew V. Schally, Trinad Chakraborty   +15 more
openalex   +1 more source

Characterization of the solution properties and conformation of pneumolysin, the membrane-damaging toxin of Streptococcus pneumoniae [PDF]

, 1993
Peter J. Morgan, Paul Varley, A. J. Rowe, Peter W. Andrew, Timothy J. Mitchell   +4 more
openalex   +1 more source

Pneumolysin-dependent and independent non-canonical autophagy processes mediate host defense against pneumococcal infection. [PDF]

Autophagy
Michno BJ, Pooranachandran N, Smith TC, Faught E, Lipowská S, Fenton AK, Meijer AH, Prajsnar TK.   +7 more
europepmc   +2 more sources

Characterization of the role that bacterial surface polysaccharide poly N-acetyl glucosamine plays in nonvaccine serotypes of streptococcus pneumoniae colonization and pathogenicity [PDF]

, 2016
Poly N-acetyl glucosamine is a cell surface polysaccharide that has been characterized in Staphylococcus epidermidis and Staphylococcus aureus as involved in biofilm formation and implicated in virulence.
Jiang, Fanny
core   +1 more source

Targeted small molecule inhibitors blocking the cytolytic effects of pneumolysin and homologous toxins [PDF]

Umer Bin Abdul Aziz, Ali Saoud, Marcel Bermúdez, Maren Mieth, Amira Atef, Thomas Rudolf, Christoph Arkona, Timo Trenkner, Christoph Böttcher, Kai Ludwig, Angelique Hœlzemer, Andreas C. Hocke, Gerhard Wolber, Jörg Rademann   +13 more
openalex   +1 more source

Active release of pneumolysin prepores and pores by mammalian cells undergoing a Streptococcus pneumoniae attack

, 2016
Heidi Wolfmeier, Julika Radecke, Roman Schoenauer, René Koeffel, Viktoria S. Babiychuk, Patrick Drücker, Lucy J. Hathaway, Timothy J. Mitchell, Benoît Zuber, Annette Draeger, Eduard B. Babiychuk   +10 more
openalex   +2 more sources

Inhibition of human polymorphonuclear leukocyte respiratory burst, bactericidal activity, and migration by pneumolysin [PDF]

, 1983
James C. Paton, Antonio Ferrante
openalex   +1 more source

Pneumolysin suppresses the initial macrophage pro‐inflammatory response to Streptococcus pneumoniae [PDF]

, 2022
Jimstan Periselneris, Carolin T. Turner, Giuseppe Ercoli, Gabriella Szylar, Caroline M. Weight, Teresa L. M. Thurston, Matthew V. X. Whelan, Gillian S. Tomlinson, Mahdad Noursadeghi, Jeremy Brown   +9 more
openalex   +1 more source

Fusion of PspA to detoxified pneumolysin enhances pneumococcal vaccine coverage. [PDF]

PLoS One, 2023
Milani B, Dos Santos TW, Guerra MES, Oliveira S, Goulart C, André GO, Leite LCC, Converso TR, Darrieux M.   +8 more
europepmc   +1 more source