Results 111 to 120 of about 5,147 (230)
Field effect transistor biosensors for healthcare monitoring
Interdisciplinary Medicine, Volume 2, Issue 4, October 2024.Amidst the growing need for healthcare monitoring, field effect transistor (FET) biosensors stand out for their high sensitivity and rapid detection capabilities. The review delves into sensor design and operational principles highlighting their application in biomarker detection for diseases.
Zhicheng Zhang +5 more
wiley +1 more source
Landscape of RNA polyadenylation in E-coli [PDF]
, 2016 Polyadenylation is thought to be involved in the degradation and quality control of bacterial RNAs but relatively few examples have been investigated.
Aurell, Erik +5 more
core +3 more sources
Strategies for Detecting Aminoacylation and Aminoacyl‐tRNA Editing in vitro and in Cells
Israel Journal of Chemistry, Volume 64, Issue 8-9, September 2024.Abstract Aminoacyl‐tRNA synthetases (aaRSs) maintain translational fidelity by ensuring the formation of correct aminoacyl‐tRNA pairs. Numerous point mutations in human aaRSs have been linked to disease phenotypes. Structural studies of aaRSs from human pathogens encoding unique domains support these enzymes as potential candidates for therapeutics ...
Rylan R. Watkins +2 more
wiley +1 more source
A type III-A CRISPR-Cas system employs degradosome nucleases to ensure robust immunity
eLife, 2019 CRISPR-Cas systems provide sequence-specific immunity against phages and mobile genetic elements using CRISPR-associated nucleases guided by short CRISPR RNAs (crRNAs).
Lucy Chou-Zheng, Asma Hatoum-Aslan
doaj +1 more source
Analysis on relationship between extreme pathways and correlated reaction sets [PDF]
, 2009 Background: Constraint-based modeling of reconstructed genome-scale metabolic networks has been successfully applied on several microorganisms. In constraint-based modeling, in order to characterize all allowable phenotypes, network-based pathways, such ...
Cao, Ming +4 more
core +3 more sources
Single‐Molecule Electrical Profiling of Peptides and Proteins
Advanced Science, Volume 11, Issue 28, July 24, 2024.This work presents a timely overview of the prominent research progress in peptide and protein‐related studies through single‐molecule electrical techniques, including single‐molecule junction, single‐molecule field‐effect transistor (FET), and nanopore.
Hongyu Ju +6 more
wiley +1 more source
Nuclear Surveillance and Degradation of Hypomodified Initiator tRNA\u3csup\u3eMet\u3c/sup\u3e in \u3cem\u3eS. cerevisiae\u3c/em\u3e [PDF]
, 2004 The tRNA m1A58 methyltransferase is composed of two subunits encoded by the essential genes TRM6 and TRM61 (formerly GCD10 and GCD14). The trm6-504 mutation results in a defective m1A methyltransferase (Mtase) and a temperature-sensitive growth phenotype
Anderson, James T. +5 more
core +1 more source
Acta Crystallographica Section A: Foundations and Advances, 2018 Polynucleotide phosphorylase (PNPase) is an evolutionary conserved 3'-to-5' exoribonuclease that functions differently among species, ranging from RNA turnover in bacteria to RNA transport in mammals.
B. Golzarroshan +3 more
semanticscholar +1 more source
ChemSystemsChem, Volume 6, Issue 4, July 2024.This review examines discoveries of biomolecular condensates as compartments in bacteria. Insights from bacterial cell biology and systems chemistry reveal intricate connections between chemical reactions and the control of condensate phase separation.
Wade E. Schnorr, W. Seth Childers
wiley +1 more source
Genome-Wide Study of mRNA Degradation and Transcript Elongation in Escherichia coli [PDF]
, 2015 An essential part of gene expression is the coordination of RNA synthesis and degradation, which occurs in the same cellular compartment in bacteria.
Chen, Huiyi +3 more
core +2 more sources