A functional RNase P protein subunit of bacterial origin in some eukaryotes [PDF]
, 2011 RNase P catalyzes 5′-maturation of tRNAs. While bacterial RNase P comprises an RNA catalyst and a protein cofactor, the eukaryotic (nuclear) variant contains an RNA and up to ten proteins, all unrelated to the bacterial protein.
Bernal Bayard, Pilar +5 more
core +1 more source
Field effect transistor biosensors for healthcare monitoring
Interdisciplinary Medicine, Volume 2, Issue 4, October 2024.Amidst the growing need for healthcare monitoring, field effect transistor (FET) biosensors stand out for their high sensitivity and rapid detection capabilities. The review delves into sensor design and operational principles highlighting their application in biomarker detection for diseases.
Zhicheng Zhang +5 more
wiley +1 more source
The crucial role of PNPase in the degradation of small RNAs that are not associated with Hfq [PDF]
RNA, 2012 The transient existence of small RNAs free of binding to the RNA chaperone Hfq is part of the normal dynamic lifecycle of a sRNA. Small RNAs are extremely labile when not associated with Hfq, but the mechanism by which Hfq stabilizes sRNAs has been elusive.
José M, Andrade +3 more
openaire +2 more sources
A type III-A CRISPR-Cas system employs degradosome nucleases to ensure robust immunity
eLife, 2019 CRISPR-Cas systems provide sequence-specific immunity against phages and mobile genetic elements using CRISPR-associated nucleases guided by short CRISPR RNAs (crRNAs).
Lucy Chou-Zheng, Asma Hatoum-Aslan
doaj +1 more source
Insights into Xanthomonas axonopodis pv. citri biofilm through proteomics [PDF]
, 2013 Background: Xanthomonas axonopodis pv. citri (X. a. pv. citri) causes citrus canker that can result in defoliation and premature fruit drop with significant production losses worldwide. Biofilm formation is an important process in bacterial pathogens and
Garavaglia, Betiana Soledad +6 more
core +1 more source
Strategies for Detecting Aminoacylation and Aminoacyl‐tRNA Editing in vitro and in Cells
Israel Journal of Chemistry, Volume 64, Issue 8-9, September 2024.Abstract Aminoacyl‐tRNA synthetases (aaRSs) maintain translational fidelity by ensuring the formation of correct aminoacyl‐tRNA pairs. Numerous point mutations in human aaRSs have been linked to disease phenotypes. Structural studies of aaRSs from human pathogens encoding unique domains support these enzymes as potential candidates for therapeutics ...
Rylan R. Watkins +2 more
wiley +1 more source
Landscape of RNA polyadenylation in E-coli [PDF]
, 2016 Polyadenylation is thought to be involved in the degradation and quality control of bacterial RNAs but relatively few examples have been investigated.
Aurell, Erik +5 more
core +3 more sources
Single‐Molecule Electrical Profiling of Peptides and Proteins
Advanced Science, Volume 11, Issue 28, July 24, 2024.This work presents a timely overview of the prominent research progress in peptide and protein‐related studies through single‐molecule electrical techniques, including single‐molecule junction, single‐molecule field‐effect transistor (FET), and nanopore.
Hongyu Ju +6 more
wiley +1 more source
Continuous enzyme-coupled assay of phosphate- or pyrophosphate-releasing enzymes
BioTechniques, 2012 A coupled enzyme assay able to monitor the kinetics of reactions catalyzed by phosphate- or pyrophosphate-releasing enzymes is presented here.
Antonio S. Guillén Suárez +4 more
doaj +1 more source
Oxygen consumption and usage during physical exercise: the balance between oxidative stress and ROS-dependent adaptive signaling. [PDF]
, 2013 The complexity of human DNA has been affected by aerobic metabolism, including endurance exercise and oxygen toxicity. Aerobic endurance exercise could play an important role in the evolution of Homo sapiens, and oxygen was not important just for ...
Atalay, Mustafa +4 more
core +1 more source