Results 71 to 80 of about 4,003 (181)
Characterization of the biochemical properties of Campylobacter jejuni RNase III
Bioscience Reports, 2013 Campylobacter jejuni is a foodborne bacterial pathogen, which is now considered as a leading cause of human bacterial gastroenteritis. The information regarding ribonucleases in C.
Nabila Haddad +4 more
doaj +1 more source
Phase Separation Regulates Metabolism, Mitochondria, and Diseases
MedComm, Volume 6, Issue 7, July 2025.Mitochondrion‐related liquid–liquid phase separation. (1) Phase separation mediates the self‐assembly of mitochondrial nucleoids (mt‐nucleoids). (2) Phase segregation mediates the formation of mitochondrial RNA granules (MRGs). (3) Phase separation mediates the formation of mitochondrial degradosomes.
Chuan Gao +3 more
wiley +1 more source
The numerous roles performed by PNPase.
, 2018 Schematic showing the functions performed by PNPase in bacteria and mitochondria. (A) In E. coli and other gram-negative bacteria, PNPase functions as part of the RNA degradosome in bulk mRNA decay but also operates independently of this machine to ...
Todd A. Cameron (146712) +2 more
core +1 more source
Nature Communications, 2020 Bacterial RNA degradation is typically initiated by endoribonucleases and followed by exoribonucleases. Here the authors report the targetome of endoRNase Y in Streptococcus pyogenes, revealing the interplay between RNase Y and 3′-to-5′ exoribonuclease ...
Laura Broglia +6 more
doaj +1 more source
Defective Processing of Cytoplasmic and Chloroplast Ribosomal RNA in the Absence of Arabidopsis DXO1
Plant, Cell &Environment, Volume 48, Issue 6, Page 4227-4244, June 2025.ABSTRACT Decapping 5′‐3′ exoribonucleases from the DXO/Rai1 family are highly conserved among eukaryotes and exhibit diverse enzymatic activities depending on the organism. The biochemical and structural properties of the plant DXO1 differ from the yeast and animal counterparts, which is reflected in the in vivo functions of this enzyme.
Monika Zakrzewska‐Placzek +5 more
wiley +1 more source
Defects in Polynucleotide phosphorylase impairs virulence in Escherichia coli O157:H7
Frontiers in Microbiology, 2015 Polynucleotide phosphorylase (PNPase) is reported to regulate virulence in Salmonella, Yersinia spp. and Campylobacter jejuni, yet its role in Escherichia coli O157:H7 has not been investigated. To gain insights into its roles in E.
Jia eHu, Jia eHu, Meijun eZhu
doaj +1 more source
Heterozygous PNPT1 Variants Cause a Sensory Ataxic Neuropathy
European Journal of Neurology, Volume 32, Issue 2, February 2025.ABSTRACT Background Biallelic variants in polyribonucleotide‐nucleotidyltransferase‐1 (PNPT1) have been associated with a range of phenotypes from syndromic hearing loss to Leigh's syndrome. More recently, heterozygous variants in PNPT1, have been reported in three families with cerebellar ataxia and prominent sensory neuropathy.
Saif Haddad +10 more
wiley +1 more source
RliB is a substrate for PNPase.
, 2014 A) In vitro PNPase activity assay. A 37 nt short P32-labeled substrate RNA (RNA37*) was incubated alone (lane 1) or with 200 nM purified PNPase (lane 2).
José Marques Andrade (275739) +9 more
core +1 more source
A Mutation in PNPT1, Encoding Mitochondrial-RNA-Import Protein PNPase, Causes Hereditary Hearing Loss [PDF]
, 2012 A subset of nuclear-encoded RNAs has to be imported into mitochondria for the proper replication and transcription of the mitochondrial genome and, hence, for proper mitochondrial function.
Richardson, Guy P. +32 more
core +1 more source
Crystal structure of the S. solfataricus archaeal exosome reveals conformational flexibility in the RNA-binding ring. [PDF]
PLoS ONE, 2010 The exosome complex is an essential RNA 3'-end processing and degradation machinery. In archaeal organisms, the exosome consists of a catalytic ring and an RNA-binding ring, both of which were previously reported to assume three-fold symmetry.Here we ...
Changrui Lu, Fang Ding, Ailong Ke
doaj +1 more source