Defective Processing of Cytoplasmic and Chloroplast Ribosomal RNA in the Absence of Arabidopsis DXO1
ABSTRACT Decapping 5′‐3′ exoribonucleases from the DXO/Rai1 family are highly conserved among eukaryotes and exhibit diverse enzymatic activities depending on the organism. The biochemical and structural properties of the plant DXO1 differ from the yeast and animal counterparts, which is reflected in the in vivo functions of this enzyme.
Monika Zakrzewska‐Placzek +5 more
wiley +1 more source
Defects in Polynucleotide phosphorylase impairs virulence in Escherichia coli O157:H7
Polynucleotide phosphorylase (PNPase) is reported to regulate virulence in Salmonella, Yersinia spp. and Campylobacter jejuni, yet its role in Escherichia coli O157:H7 has not been investigated. To gain insights into its roles in E.
Jia eHu, Jia eHu, Meijun eZhu
doaj +1 more source
Genome-Wide Study of mRNA Degradation and Transcript Elongation in Escherichia coli [PDF]
An essential part of gene expression is the coordination of RNA synthesis and degradation, which occurs in the same cellular compartment in bacteria.
Chen, Huiyi +3 more
core +2 more sources
Background Transition from planktonic cells to biofilm is mediated by production of adhesion factors, such as extracellular polysaccharides (EPS), and modulated by complex regulatory networks that, in addition to controlling production of adhesion ...
Carzaniga Thomas +4 more
doaj +1 more source
Looping forward: exploring R‐loop processing and therapeutic potential
R‐loops function as both regulators of gene expression, DNA repair, telomere maintenance or chromosome segregation, and as drivers of genome instability. This dual nature of these structures is coordinated by RNA/DNA/chromatin processing factors that safeguard the genome from detrimental R‐loop‐instigated DNA damage or cellular dysfunction ...
Kalliopi Stratigi +2 more
wiley +1 more source
Streptomyces natalensis programmed cell death and morphological differentiation are dependent on oxidative stress [PDF]
Streptomyces are aerobic Gram-positive bacteria characterized by a complex life cycle that includes hyphae differentiation and spore formation.
Beites, Tiago +8 more
core +2 more sources
Analysis of real‐world cross‐sectional study data revealed relative errors between the standard method and ICP‐MS for the different minerals tested. Additionally, several outliers were observed exclusively in the ICP‐MS results, likely due to hemolysis or other unidentified factors.
Kosuke Kojo +10 more
wiley +1 more source
Mitochondrial sequencing identifies long noncoding RNA features that promote binding to PNPase.
Long noncoding RNAs (lncRNAs) are relatively novel RNAs with increasingly prominent roles in regulating genetic expression, mainly in the nucleus but more recently in regions such as the mitochondrion. This study explores how lncRNAs interact with polynucleotide phosphorylase (PNPase), a protein that regulates RNA import into the mitochondrion ...
Taylor AD +16 more
europepmc +3 more sources
Nuclear Surveillance and Degradation of Hypomodified Initiator tRNA\u3csup\u3eMet\u3c/sup\u3e in \u3cem\u3eS. cerevisiae\u3c/em\u3e [PDF]
The tRNA m1A58 methyltransferase is composed of two subunits encoded by the essential genes TRM6 and TRM61 (formerly GCD10 and GCD14). The trm6-504 mutation results in a defective m1A methyltransferase (Mtase) and a temperature-sensitive growth phenotype
Anderson, James T. +5 more
core +1 more source
Novel resources to investigate leaf plasmodesmata formation in C3 and C4 monocots
SUMMARY Plasmodesmata (PD) are nanochannels that facilitate cell‐to‐cell transport in plants. More productive and photosynthetically efficient C4 plants form more PD at the mesophyll (M)‐bundle sheath (BS) interface in their leaves than their less efficient C3 relatives.
Hong Ting Tsang +4 more
wiley +1 more source

