Results 21 to 30 of about 41,440 (279)
Podocyte Mitosis - A Catastrophe [PDF]
Current Molecular Medicine, 2012 Podocyte loss plays a key role in the progression of glomerular disorders towards glomerulosclerosis and chronic kidney disease. Podocytes form unique cytoplasmic extensions, foot processes, which attach to the outer surface of the glomerular basement membrane and interdigitate with neighboring podocytes to form the slit diaphragm.
LASAGNI, LAURA +4 more
openaire +3 more sources
Angiopoietin-Like-4, a Potential Target of Tacrolimus, Predicts Earlier Podocyte Injury in Minimal Change Disease. [PDF]
PLoS ONE, 2015 Podocyte injury plays central roles in proteinuria and kidney dysfunction, therefore, identifying specific biomarker to evaluate earlier podocyte injury is highly desirable.
Jian-Si Li +10 more
doaj +1 more source
A new outlook towards kidney injuries [PDF]
, 2012 Acute and chronic progression of injury to the kidney leads to the failure of the renal system and has become an increasingly important cause of morbidity and mortality.
Abhijeet Satwekar, Mahesh Satwekar
core +2 more sources
CXCL16 and oxLDL are induced in the onset of diabetic nephropathy [PDF]
, 2009 Diabetic nephropathy (DN) is a major cause of end-stage renal failure worldwide. Oxidative stress has been reported to be a major culprit of the disease and increased oxidized low density lipoprotein (oxLDL) immune complexes were found in patients with ...
Abdel-Aziz, Abdel-Aziz H. +11 more
core +1 more source
Podocyte Biology and the Emerging Understanding of Podocyte Diseases [PDF]
American Journal of Nephrology, 2003 The understanding of the unique molecular apparatus of the podocyte has increased dramatically in recent years. This new knowledge has improved the diagnosis and classification of the diseases that have been termed podocytopathies. Podocyte injury frequently leads to reorganization of the slit diaphragm and reorganization of the foot process structure.
Laura, Barisoni, Peter, Mundel
openaire +2 more sources
BMC Nephrology, 2006 Background A reduction in the number of podocytes and podocyte density has been documented in the kidneys of patients with diabetes mellitus. Additional studies have shown that podocyte injury and loss occurs in both diabetic animals and humans. However,
Sullivan Kelli A +4 more
doaj +1 more source
Whole carcass diets: a role for fibre in gastrointestinal health of cheetahs? [PDF]
, 2011 This study was undertaken to test the hypothesis that altered podocyte slit protein nephrin distribution is associated with disturbed polarity protein expressions in podocytes from preeclampsia (PE).
Depauw, Sarah +6 more
core +2 more sources
Podocytes: recent biomolecular developments [PDF]
Biomolecular Concepts, 2014 AbstractPodocytes are postmitotic renal glomerular cells with multiple ramifications that extend from the cell body. Processes departing from a podocyte interdigitate with corresponding projections from neighboring cells and form an intricate web that enwraps the glomerular capillary completely.
Armelloni, Silvia +9 more
openaire +4 more sources
Erk5 is a mediator to TGFβ1-induced loss of phenotype and function in human podocytes. [PDF]
, 2014 Background: Podocytes are highly specialized cells integral to the normal functioning kidney, however, in diabetic nephropathy injury occurs leading to a compromised phenotype and podocyte dysfunction which critically produces podocyte loss with ...
Binder +39 more
core +2 more sources
Podocyte Lipotoxicity in CKD [PDF]
Kidney360, 2021 CKD represents the ninth most common cause of death in the United States but, despite this large health burden, treatment options for affected patients remain limited. To remedy this, several relevant pathways have been identified that may lead to novel therapeutic options.
Jin-Ju, Kim +2 more
openaire +2 more sources