Journal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.ABSTRACT Tubulointerstitial fibrosis (TIF) significantly contributes to the development of end‐stage renal disease (ESRD) in chronic kidney disease (CKD). However, the underlying mechanisms driving its development remain poorly understood, thereby impeding the development of effective prevention and treatment strategies. Although growth differentiation
Youqi Li +8 more
wiley +1 more source
Podocyte puzzle: IgA nephropathy
Clinical Kidney Journal, 2023 Joyita Bharati +2 more
openaire +2 more sources
Exploring Bilirubin’s Impact on Autophagy and Apoptosis in Diabetic Kidney Disease
BioMed Research International, Volume 2026, Issue 1, 2026.Background Diabetic kidney disease (DKD) affects nearly half of patients with type 1 or type 2 diabetes and is a leading cause of end‐stage renal disease (ESRD). Maladaptive autophagy and increased apoptosis have been observed in diabetic kidneys. Bilirubin, a natural antioxidant, may exert protective effects against DKD progression; however, the ...
Mohammad Hasan Maleki +9 more
wiley +1 more source
The protective effect and mechanism of catalpol on high glucose-induced podocyte injury [PDF]
, 2019 Yan Chen +7 more
openalex +1 more source
Growth hormone induces TNF-α in podocytes and contributes to monocyte-to-macrophage differentiation: Implications in Diabetic kidney disease [PDF]
, 2022 Anil Kumar Pasupulati +6 more
openalex +1 more source
The Role and Clinical Significance of miR‐484 in the Regulation of SGLT2 in Diabetic Nephropathy
International Journal of Endocrinology, Volume 2026, Issue 1, 2026.Background Diabetic nephropathy (DN), a severe complication of Type 2 diabetes mellitus (T2DM), is the primary reason of end‐stage kidney disease (ESKD) and is closely associated with an elevated cardiovascular risk. While miR‐484 has been implicated in diabetes, its specific role in DN remains to be elucidated.
Wendi Zhao +5 more
wiley +1 more source
Effect of Irbesartan on TRPC6 expression in high glucose-induced mouse podocytes
Linchuang shenzangbing zazhi, 2016 Objective To study the effect of irbesartan（angiotensin Ⅱ receptor blocker） on the expression of TRPC6 in high glucose-induced conditional immortalized mouse podocytes.Methods The conditional immortalized mouse podocytes were cultured in vitro and ...
HU Chun-li +2 more
doaj
Detection and Quantification of Lipid Droplets in Differentiated Human Podocytes
, 2019 Shamroop Kumar Mallela +5 more
openalex +2 more sources
Soluble RARRES1 induces podocyte apoptosis to promote glomerular disease progression [PDF]
, 2020 Anqun Chen +15 more
openalex +1 more source
Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
The FASEB Journal, Volume 39, Issue 24, 31 December 2025.Mechanistic summary of how autocrine ANG2 suppressed LMEC proliferation. Somatic activating SNVs in PIK3CA result in increased PI3K/Akt signaling, Akt‐mediated downregulation of ANG2, and LMEC hyperproliferation. Restoration of autocrine ANG2 in LMECs through overexpression suppressed LMEC proliferation in vitro and lymphangiogenesis in vivo and was ...
Ravi W. Sun +10 more
wiley +1 more source