Results 91 to 100 of about 8,560 (165)

Medicinal plants-based foods for breast cancer treatment: An ethnobotanical survey and digitization [PDF]

open access: yes, 2013
One million new breast cancer (BC) cases diagnosed yearly yielded over 400,000 annual deaths. About 4.4 million women are living with BC worldwide, while 15 million new cases yearly are estimated by 2020.
Omogbadegun, Zacchaeus Oni
core  

Micropropagation for the production of high quality phytochemicals [PDF]

open access: yes, 2013
Plants area source of many valuable secondary metabolites that find a broad field of applications, ranging from the agrochemical to the pharmaceutical industries.
Grevenstuk, Tomás, Romano, Anabela
core   +1 more source

Endophytic Fungi—Alternative Sources of Cytotoxic Compounds: A Review

open access: yesFrontiers in Pharmacology, 2018
Cancer is a major cause of death worldwide, with an increasing number of cases being reported annually. The elevated rate of mortality necessitates a global challenge to explore newer sources of anticancer drugs.
Fazilath Uzma   +12 more
doaj   +1 more source

GuiErBai: a potent inhibitor, exhibiting broadly antitumor effect against cervical cancer in vitro and in vivo

open access: yesFrontiers in Pharmacology
Introduction: Cervical cancer (CC) ranks as the fourth most prevalent malignant tumor among women worldwide, and is the fourth leading cause of cancer-related mortality.
Hong-en Qin   +10 more
doaj   +1 more source

Treatment for Condyloma Acuminatum with Graves’ disease [PDF]

open access: yes, 2016
SAS Publisher's journals are open access journals.A rare case of external genital condylomata acuminatum with Graves’ disease was reported. The cauliflower warts were observed on glans penis and foreskin of a 40-year-old man, who had typical Graves ...
Ji Luo, Nian, Tang, Ning
core   +1 more source

Exploring the mechanism of enterotoxicity mediated by the microbiome-butyrate-PPAR axis in podophyllotoxin through the toxicological evidence chain (TEC) concept

open access: yesEcotoxicology and Environmental Safety
Podophyllotoxin (PPT) is a lignan derived from the roots and stems of the Podophyllum plant. However, its enterotoxicity restricts its clinical application. The underlying mechanisms by which PPT exerts its action remain largely elusive. This study aimed
Jiajia Duan   +7 more
doaj   +1 more source

Design, Synthesis, and Cytotoxicity of Perbutyrylated Glycosides of 4β-Triazolopodophyllotoxin Derivatives

open access: yesMolecules, 2015
A series of novel perbutyrylated glycosides of 4β-triazolopodophyllotoxin derivatives were synthesized by utilizing the copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction.
Cheng-Ting Zi   +7 more
doaj   +1 more source

Therapy of cancer by insect cells containing recombinant baculovirus encoding genes [PDF]

open access: yes, 2002
Provided are compositions and methods of use for insect cells comprising baculovirus encoding non-surface expressed proteins and peptides. The claimed invention particularly relates to compositions comprising insect cells containing baculovirus that ...
Dhong, Zhongyun   +2 more
core   +1 more source

LIM kinase inhibitors disrupt mitotic microtubule organization and impair tumor cell proliferation [PDF]

open access: yes, 2015
The actin and microtubule cytoskeletons are critically important for cancer cell proliferation, and drugs that target microtubules are widely-used cancer therapies. However, their utility is compromised by toxicities due to dose and exposure. To overcome
Baugh, Mark   +18 more
core   +2 more sources

Glucoside Derivatives Of Podophyllotoxin: Synthesis, Physicochemical Properties, And Cytotoxicity

open access: yesDrug Design, Development and Therapy, 2019
Cheng-Ting Zi,1,2,* Liu Yang,2,* Qing-Hua Kong,2 Hong-Mei Li,2 Xing-Zhi Yang,2 Zhong-Tao Ding,3 Zi-Hua Jiang,4 Jiang-Miao Hu,2 Jun Zhou2 1Key Laboratory of Pu-Er Tea Science, Ministry of Education, College of Science, Yunnan Agricultural University ...
Zi CT   +8 more
doaj  

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