Results 21 to 30 of about 8,560 (165)

De novo transcriptome analysis using 454 pyrosequencing of the Himalayan Mayapple,Podophyllum hexandrum [PDF]

, 2013
Background: The Himalayan or Indian Mayapple (Podophyllum hexandrum Royle) produces podophyllotoxin, which is used in the production of semisynthetic anticancer drugs.
Bhattacharyya, Dipto, Chattopadhyay, Sharmila, Datta, Riddhi, Hazra, Saptarshi, Sinha, Ragini   +4 more
core   +1 more source

Cytotoxic activity and chemical composition of the root extract from the mexican species Linum scabrellum: mechanism of action of the active compound 6-Methoxypodophyllotoxin [PDF]

, 2015
12 p.-6 fig.-1 tab.The cytotoxic activity and the chemical composition of the dichloromethane/methanol root extract of Linum scabrellum Planchon (Linaceae) were analyzed. Using NMR spectra and mass spectrometry analyses of the extract we identified eight
Alejandre-García, Ivonne, Antúnez-Mojica, Mayra, Cardoso-Taketa, Alexandre, Díaz, José Fernando, González-Maya, Leticia, Marquina-Bahena, Silvia, Salas-Vidal, Enrique, Villarreal, María Luisa, Álvarez, Laura   +8 more
core   +3 more sources

A Friendly Relationship between Endophytic Fungi and Medicinal Plants: A Systematic Review [PDF]

, 2016
Endophytic fungi or endophytes exist widely inside the healthy tissues of living plants, and are important components of plant micro-ecosystems. Over the long period of evolution, some co-existing endophytes and their host plants have established a ...
Abd_Allah, Ahmad, Amna, Bacon, Barazani, Bashyal, Behie, Bittleston, Bussaban, Camatti-Sartori, Cao, Cao, Carroll, Cavaglieri, Chakravarthi, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Chithra, Chutima, Cui, D'Amico, Dai, Deng, Dingle, Duan, Eyberger, Faeth, Fan, Firáková, Gangadevi, Gangadevi, Gange, Gao, Gunatilaka, Guo, Guo, Guo, Gómez-Vidal, Harper, Hartley, Herrera-Carrillo, Huang, Huang, Jiang, Ju, Khan, Kim, Kour, Kozyrovska, Kumaran, Kumaran, Kusari, Kusari, Kusari, Kusari, Kusari, Kusari, Li, Li, Li, Li, Li, Li, Liu, Liu, Lu, Maciá-Vicente, Maehara, Meng, Ming, Mo, Moricca, Nascimento, Nejad, Osono, Pan, Puri, Puri, Qiu, Qiu, Redman, Rehman, Ren, Richardson, Rodrigues, Rodriguez, Rodriguez, Saikkonen, Saikkonen, Senthil Kumaran, Sherameti, Shrestha, Shwab, Shweta, Sieber, Silva, Song, Stierle, Stierle, Strobel, Strobel, Strobel, Sumarah, Sun, Sun, Suryanarayanan, Tan, Tang, Tofern, Torres, Unterseher, Venkatachalam, Wang, Wang, Wang, Wang, Wang, Wang, Waqas, Weyens, Wu, Yan, Yang, Yang, Yin, Yu, Zeng, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhao, Zhao, Zhou, Zhou   +141 more
core   +1 more source

Imiquimod versus podophyllotoxin, with and without human papillomavirus vaccine, for anogenital warts: the HIPvac factorial RCT

Health Technology Assessment, 2020
Background: The comparative efficacy, and cost-effectiveness, of imiquimod or podophyllotoxin cream, either alone or in combination with the quadrivalent HPV vaccine (Gardasil®, Merck Sharp & Dohme Corp., Merck & Co., Inc., Whitehouse Station, NJ, USA ...
Richard Gilson, Diarmuid Nugent, Kate Bennett, Caroline J Doré, Macey L Murray, Jade Meadows, Lewis J Haddow, Charles Lacey, Frank Sandmann, Mark Jit, Kate Soldan, Michelle Tetlow, Emilia Caverly, Mayura Nathan, Andrew J Copas   +14 more
doaj   +1 more source

Untersuchungen zur Rolle von Cytochrom P450-Enzymen in der Biosynthese von Aryltetralin-Lignanen in Zellkulturen von Linum spec. [PDF]

, 2004
Lignane sind phenolische Verbindungen des pflanzliche Sekundärstoffwechsels, die sich von der Aminosäure Phenylalanin ableiten, über das Pflanzenreich weit verbreitet sind und die vielfältige pharmazeutisch-medizinische Bedeutungen haben können ...
Kuhlmann, Stephan, Petersen, Maike (Professor Dr.)   +1 more
core   +1 more source

Dual extraction of essential oil and podophyllotoxin from creeping juniper (Juniperus horizontalis).

PLoS ONE, 2014
Juniperus horizontalis Moench (Family Cupressaceae), commonly called creeping juniper, is a widely distributed species in the United States and much of Canada.
Charles L Cantrell, Valtcho D Zheljazkov, Camila R Carvalho, Tess Astatkie, Ekaterina A Jeliazkova, Luiz H Rosa   +5 more
doaj   +1 more source

Antitumor activity of a novel dual functional podophyllotoxin derivative involved PI3K/AKT/mTOR pathway.

PLoS ONE, 2019
The progression of cancer through local expansion and metastasis is well recognized, but preventing these characteristic cancer processes is challenging. To this end, a new strategy is required.
Yongli Li, Tengfei Huang, Yun Fu, Tingting Wang, Tiesuo Zhao, Sheng Guo, Yanjie Sun, Yun Yang, Changzheng Li   +8 more
doaj   +1 more source

Study on the podophyllotoxin in the Dysosma versipellis (Hance) M. Cheng and its Callus' Materials

浙江大学学报. 农业与生命科学版, 2006
In this study, HPLC was used to detect the podophyllotoxin content in three parts of Dysosma versipellis (Hance). The content was 0.60% in the wild root, while in the calli and the induced root from this calli, they were 0.117% and 0.148%, respectively ...
PAN Qi, CHEN Shao-yuan, JIANG Wei-mei, Gilbert Y S Chan, FU Cheng-xin   +4 more
doaj   +1 more source

DISTRIBUIÇÃO, ATIVIDADE BIOLÓGICA, SÍNTESE E MÉTODOS DE PURIFICAÇÃO DE PODOFILOTOXINA E SEUS DERIVADOS

Química Nova, 2015
Podophyllotoxin is the most studied lignan because of its use as an antimitotic agent and because it is a precursor of pharmacologically active derivatives.
Héctor Hugo S. Medrado, Jorge M. David, Juceni P. David, Hugo N. Brandão   +3 more
doaj   +1 more source

Mechanism of podophyllotoxin-induced ovarian toxicity via the AMPK/TSC1/mTOR/ULK1 axis in rats on the basis of toxicological evidence chain (TEC) concept

Ecotoxicology and Environmental Safety
Background: Podophyllotoxin is a compound with clinical effects, such as anticancer and antiacromegaly effects, but its systemic toxicity has led to extremely limited clinical application.
Jingjing Li, Yanzhao Zhang, Mingyue Wei, Junjie He, Huifeng Ma, Zilong Chen, Jiajia Duan, Chuanxin Liu   +7 more
doaj   +1 more source