Results 31 to 40 of about 8,560 (165)
Induction of defensive responses and production of secondary metabolites in Linum album cell culture by ultrasound [PDF]
Zīst/shināsī-i Giyāhī-i Īrān, 2015 Ultrasound (US) with low intensity is considered as a physical tool to stimulate living systems in medicine and biotechnology. This study aim to survey the US effects on some physiological parameters and podophyllotoxin production in Linum album cell ...
Armaghan Abedzadeh Neyshabouri +1 more
doaj
Inhibition of cytochrome P450 activities by extracts of 'Hyptis verticillata' Jacq. : assessment for potential HERB-drug interactions [PDF]
, 2018 Understanding the potential for adverse drug reactions (ADRs), from herb-drug interactions, is a key aspect of medicinal plant safety, with particular relevance for public health in countries where medicinal plant use is highly prevalent. We undertook an
Barker, James +6 more
core +2 more sources
Molecules, 2012 The hydroalcoholic extract of the steam bark of <em>B. fagaroides</em> var. <em>fagaroides</em> displayed potent cytotoxic activity against four cancer cell lines, namely KB (ED<sub>50</sub> = 9.6 × 10<sup>−2</
Laura Alvarez +8 more
doaj +1 more source
Reduction-Hypersensitive Podophyllotoxin Prodrug Self-Assembled Nanoparticles for Cancer Treatment
Pharmaceutics, 2023 Podophyllotoxin (PPT) has shown strong antitumor effects on various types of cancers. However, the non-specific toxicity and poor solubility severely limits its clinical transformation.
Xinhui Wang +6 more
doaj +1 more source
The Polymorphism of Model United Nations: Students’ Guide [PDF]
This guide serves as a comprehensive introduction to Model United Nations (MUN), an educational simulation designed to immerse students in the dynamics of international diplomacy and decision-making. MUN conferences allow participants to assume the roles
Maruthi, T. R., Shahbaz, Syed
core +1 more source
VIEW, EarlyView.The limitations of conventional techniques hinder the identification of natural compounds with anticancer potential in terms of speed, throughput, sensitivity, and capability of continuous monitoring of relevant biological effects. Novel label‐free optical biosensors represent new opportunities in the discovery of drug candidates, eliminating these ...
Beatrix Péter +10 more
wiley +1 more source
Targeting Kinetoplastid Parasites with ProTide Prodrugs: A Proof‐of‐Concept Study
ChemMedChem, Volume 21, Issue 7, 14 April 2026.Neglected tropical diseases (NTDs) remain a major global health challenge, particularly in low‐ and middle‐income countries. Kinetoplastid parasites causing Chagas disease, leishmaniasis, and African trypanosomiasis rely on host purine salvage pathways, making nucleoside analogues attractive therapeutic candidates.
Silvester Lowe +6 more
wiley +1 more source
, 2017 Oral hairy leukoplakia (OHL) is a disease of the mucosa first described in 1984. This pathology is associated with Epstein-Barr virus (EBV) and occurs mostly in people with HIV infection, both immunocompromised and immunocompetent, and can affect ...
Agarwala, Sanjiv S. +5 more
core +1 more source
Cancer Medicine, Volume 15, Issue 3, March 2026.Etoposide mediated topoisomerase II inhibition in Cervical Cancer. ABSTRACT Background Etoposide is a semisynthetic derivative of podophyllotoxin and an FDA‐approved topoisomerase II inhibitor that induces DNA strand breaks leading to cancer cell death.
Nikitha Kotian +3 more
wiley +1 more source
Purity Assessment of Aryltetralin Lactone Lignans by Quantitative 1H Nuclear Magnetic Resonance
Molecules, 2015 In the present work, a quantitative 1H Nuclear Magnetic Resonance (qHNMR) was established for purity assessment of six aryltetralin lactone lignans. The validation of the method was carried out, including specificity, selectivity, linearity, accuracy ...
Yan-Jun Sun +7 more
doaj +1 more source