Results 81 to 90 of about 8,560 (165)
MoleculesPodophyllotoxin, a cyclolignan natural product, has been the object of extensive chemomodulation to obtain better chemotherapeutic agents. Among the obtained podophyllotoxin derivatives, podophyllic aldehyde showed very interesting potency and ...
Pablo A. García +7 more
doaj +1 more source
Alkoxy- and hydroxycyclization of enynes catalyzed by Pd(II) and Pt(II) catalysts [PDF]
, 2006 The development of a novel reaction ideal in terms of atom economy was achieved. The scope of the reaction was evaluated in the presence of Pd and Pt catalysts.
Charruault, Lise +3 more
core
Cytotoxicity of Libyan Juniperus phoenicea against Human Cancer Cell Lines A549, EJ138, Hepg2 and MCF7 [PDF]
Background: The current study was undertaken to assess the cytotoxicity of the leaves of Libyan Juniperus phoenicea (Cupressaceae) against human cancer cell lines.
Aboul-Ela M +7 more
core +1 more source
ChemMedChem, Volume 20, Issue 17, September 11, 2025.BP(1‐6) compounds designed from Benzoxazole and Thiazolyl‐Pyrazole scaffolds exhibited potent antitubulin and caspase‐3 activity in MDA‐MB‐231 cells. BP‐6 notably triggered apoptosis and disrupted cell proliferation. Docking studies validated strong binding affinities of BP‐2 and BP‐6 toward β‐tubulin and caspase‐3, suggesting promising therapeutic ...
Burak Kuzu +3 more
wiley +1 more source
Chemistry &Biodiversity, Volume 22, Issue 8, August 2025.ABSTRACT Cancer is a major global health concern. Therefore, new treatment options are needed. The phytochemicals have different chemical structures. It also exhibits several other biological activities. Therefore, these compounds are promising anticancer agents. This review aims to identify and assess new candidates for anticancer therapy. Researchers
Alaa A. A. Aljabali +11 more
wiley +1 more source
In vitro germination of Podophyllum hexandrum seeds.
Ornamental Horticulture, 2007 Considerable interest has centred on the Podophyllum-based lignans as lead compounds for the development of new drugs. The successful introduction of the anticancer drugs etoposide® and teniposide® and the development of new derivatives such as ...
Cláudia Gontijo Silva +3 more
doaj +1 more source
Human papillomavirus vaccine effectiveness by number of doses: Systematic review of data from national immunization programs. [PDF]
, 2018 BACKGROUND: Human papillomavirus (HPV) vaccines were first licensed as a three-dose series; a two-dose series is now recommended in some age groups and there is interest in possible one-dose vaccination.
Brisson, Marc +4 more
core +1 more source
SYNTHESIS AND CHARACTERIZATION OF NEW PODOPHYLLOTOXIN DERIVATIVE
Avances en Ciencias e Ingeniería, 2014 In this paper, the synthesis and the spectroscopic study for the characterization of a new podophyllotoxin derivate is described. Podophyllotoxin 1 was isolated from the commercial resin of Podophyllum emodi W., that was used as starting material ...
Amalyn Nain-Pérez +3 more
doaj
Pharmakologische Studien über Podophyllum peltatum / von Valerian Podwyssotzki [PDF]
, 2011 Das Rhizom von Podophyllum peltatum (amerik. Mayapple; mandrake) wird seit dem Ende des vorigen Jahrhunderts in Nordamerika auf Grund seiner emetischen und purgirenden Wirkungen als Arzneimittel gebraucht..
Podvysockij, Vladimir V.
core
Antiprotozoal activity and cytotoxicity of Lycopodium clavatum and Lycopodium complanatum subsp. chamaecyparissus extracts [PDF]
, 2013 Objective: the aim of this study is to investigate the in vitro antioxidant activity, the total phenol and flavonoid content and the possible protective effects of commercial propolis on gentamicin-induced nephrotoxicity in rabbits.
Brun, Reto +5 more
core +1 more source