Results 21 to 30 of about 19,338 (290)

Serum Podoplanin Levels as a Potential Biomarker for Diabetic Nephropathy Progression: A Cross-Sectional Study [PDF]

Diabetes, Metabolic Syndrome and Obesity
Feng Huan,1 Xia Jiang2 1Public Health Medical Prevention Collaboration Department, First People’s Hospital, Nantong City, Jiangsu, 226014, People’s Republic of China; 2Department of Nephrology, Nantong Rehabilitation Hospital (Nantong Second People’s ...
Huan F, Jiang X
doaj   +2 more sources

CLEC-2/podoplanin and thromboinflammation [PDF]

Blood, 2017
In this issue of Blood, Payne et al revealed a novel function of the platelet C–type lectin-like receptor 2 (CLEC-2)/podoplanin interaction in thromboinflammation: podoplanin expression is upregulated in the vessel wall during venous thrombosis. Venous thrombosis is prevented in the absence of CLEC-2.1 The role of platelet CLEC-2 in thromboinflammation
Katsue Suzuki‐Inoue
openalex   +3 more sources

Podoplanin Expression and the Risk of Malignant Transformation of Oral Pre-Malignant Disease: A Systematic Review and Meta-Analysis. [PDF]

Head Neck
ABSTRACT Background Podoplanin is a mucin‐like transmembrane glycoprotein expressed in oral epithelium with a documented role in cell motility, tumorigenesis, tumor invasion, and metastasis. Podoplanin is a potentially valuable biomarker for determining malignant transformation of oral premalignant disease (OPMD).
Briggs EE, Schlosser N, Nguyen SA, Graboyes E, Newman JG, Kejner AE, Albergotti G, Bobian M, Yoon A, Peterson Y, Adilbay D.   +10 more
europepmc   +2 more sources

Podoplanin expression in primary brain tumors induces platelet aggregation and increases risk of venous thromboembolism [PDF]

Blood, 2017
Julia Riedl, Matthias Preusser, Pegah Mir Seyed Nazari, Florian Posch, Simon Panzer, Christine Marosi, Peter Birner, J. Thaler, Christine Brostjan, Daniela Lötsch, Walter Berger, Johannes A. Hainfellner, Ingrid Pabinger, Cihan Ay   +13 more
openalex   +2 more sources

Co-Expression of Podoplanin and CD44 in Proliferative Vitreoretinopathy Epiretinal Membranes

International Journal of Molecular Sciences, 2023
Epiretinal membranes (ERMs) are sheets of tissue that pathologically develop in the vitreoretinal interface leading to progressive vision loss. They are formed by different cell types and by an exuberant deposition of extracellular matrix proteins ...
Denise Bonente, L. Bianchi, R. De Salvo, C. Nicoletti, Elena De Benedetto, Tommaso Bacci, L. Bini, Giovanni Inzalaco, Lorenzo Franci, M. Chiariello, G. Tosi, E. Bertelli, Virginia Barone   +12 more
semanticscholar   +1 more source

Podoplanin immunopositive lymphatic vessels at the implant interface in a rat model of osteoporotic fractures [PDF]

, 2013
Insertion of bone substitution materials accelerates healing of osteoporotic fractures. Biodegradable materials are preferred for application in osteoporotic patients to avoid a second surgery for implant replacement. Degraded implant fragments are often
Alt, Volker, Gelinsky, Michael, Hanke, Thomas, Hartmann, Sonja, Heinemann, Sascha, Heiss, Christian, Kampschulte, Marian, Kauschke, Vivien, Kautz, Armin R., Kilian, Olaf, Langheinrich, Alexander, Lips, Katrin Susanne, Ray, Seemun, Schnabelrauch, Matthias, Schnettler, Reinhard, Schumacher, Matthias, Thormann, Ulrich   +16 more
core   +10 more sources

Podoplanin: A potential therapeutic target for thrombotic diseases

Frontiers in Neurology, 2023
As a specific lymphatic marker and a key ligand of C-type lectin-like receptor 2 (CLEC-2), podoplanin (Pdpn) is involved in various physiological and pathological processes such as growth and development, respiration, blood coagulation, lymphangiogenesis,
Ya-Qun Huang, Manli Lu, Yi Wang, Chun-yuan Zhang, Yongjun Cao, Xia Zhang   +5 more
semanticscholar   +1 more source

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

Hepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog, Reika Fujiwara, Stephanie Q. Pan, Khairat B. El‐Baradie, Hye Yeon Choi, Sonal Sinha, Qihong Yang, Kinji Asahina, Yibu Chen, Meng Li, Matthew Salomon, Stanley W.‐K. Ng, Hidekazu Tsukamoto   +12 more
wiley   +1 more source

Detection of Lion Podoplanin Using the Antitiger Podoplanin Monoclonal Antibody PMab-231 [PDF]

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, 2020
Monoclonal antibodies (mAbs) that specifically target podoplanin (PDPN), a marker for type I alveolar cells, are needed for immunohistochemical analyses. Anti-PDPN mAbs are available for many species, including human, mouse, rat, rabbit, dog, cat, bovine, pig, Tasmanian devil, alpaca, tiger, whale, goat, horse, bear, and sheep PDPNs.
Yusuke Sayama, Junko Takei, Teizo Asano, Kazuyuki Uchida, Yukinari Kato, Mika K. Kaneko, Takayuki Nakagawa, Masato Sano   +7 more
openaire   +3 more sources

Near-Infrared Photoimmunotherapy Targeting Podoplanin-Expressing Cancer Cells and Cancer-Associated Fibroblasts.

Molecular Cancer Therapeutics, 2022
Near-infrared photoimmunotherapy (NIR-PIT) is a new cancer treatment that utilizes an antibody-IRDye700DX (IR700) conjugate that binds to a target followed by the application of NIR light that results in dramatic changes in solubility of the conjugate ...
T. Kato, Aki Furusawa, Ryuhei Okada, Fuyuki F Inagaki, H. Wakiyama, H. Furumoto, Hiroshi Fukushima, Shuhei Okuyama, P. Choyke, Hisataka Kobayashi   +9 more
semanticscholar   +1 more source