Results 41 to 50 of about 13,097 (241)
Molecular Cancer, 2010 Background Podoplanin, a mucin-like transmembrane glycoprotein, is reportedly expressed in a variety of malignant cells and is generally regarded as a factor for promoting tumor progression in conventional studies.
Suzuki Hanako +5 more
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Roles of the CLEC-2–podoplanin interaction in tumor progression
Platelets, 2018 Podoplanin is a type-I transmembrane sialomucin-like glycoprotein expressed on the surface of several kinds of tumor cells. The podoplanin receptor is a platelet activation receptor known as C-type lectin-like receptor 2 (CLEC-2), which has been ...
Katsue Suzuki-Inoue
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Interplay between Podoplanin, CD44s and CD44v in Squamous Carcinoma Cells
Cells, 2020 Podoplanin and CD44 are transmembrane glycoproteins involved in inflammation and cancer. In this paper, we report that podoplanin is coordinately expressed with the CD44 standard (CD44s) and variant (CD44v) isoforms in vivo—in hyperplastic skin after a ...
Lucía Montero-Montero +7 more
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The Role of Podoplanin in Skin Diseases
International Journal of Molecular Sciences, 2022 Podoplanin is a sialomucin-like type I transmembrane receptor glycoprotein that is expressed specifically in lymphatic vessels, sebaceous glands, and hair follicles in normal skin.
J. Asai
semanticscholar +1 more source
Assessment of expression of podoplanin in odontogenic tumors and cysts—An immunohistochemical study
Journal of Family Medicine and Primary Care, 2020 Aim: The present study was conducted to determine the podoplanin expression in odontogenic tumors and cysts. Materials and Methods: It consisted of 12 cases of the keratocystic odontogenic tumor (KCOT), 10 cases of ameloblastoma, 8 cases of dentigerous ...
Rohit Singh +5 more
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Platelets, 2018 Lymphatic endothelial cells (LEC) express the transmembrane receptor podoplanin whose only known endogenous ligand CLEC-2 is found on platelets. Both podoplanin and CLEC-2 are required for normal lymphangiogenesis as mice lacking either protein develop a
Stacey A. Langan +3 more
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Are podoplanin and ezrin involved in the invasion process of the ameloblastomas?
European Journal of Histochemistry, 2015 The association between podoplanin and ezrin in the process of odontogenic tumors invasion has been suggested, but was not studied yet. Our purpose was to investigate the relationship between podoplanin and ezrin expressions in the odontogenic epithelium
Y.F. Costa +5 more
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Indian Journal of Dental Sciences, 2021 Background: Odontogenic lesions can bring about diagnostic challenges due to overlapping histology among pathologists. Thus, there are few tumor markers that provide accurate diagnosis.
Alka Chahar +4 more
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International Journal of Biological Markers, 2022 Introduction Head and neck squamous cell carcinomas (HNSCCs) are cancers with generally poor prognosis. Outcomes have not improved in decades, with more than half of the patients presenting with lymph node metastases at the time of diagnosis.
J. Kühn +10 more
semanticscholar +1 more source
New trends in the study of podoplanin as a cell morphological regulator
Japanese Dental Science Review, 2010 Podoplanin is a mucin-type glycoprotein firstly identified in podocytes, which is homologous to the type I alveolar cell specific T1α-2 antigen and to the oncofetal antigen M2A recognized by the D2-40 antibody. Podoplanin possesses a platelet aggregation-
Yoshihiko Sawa
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