Results 111 to 120 of about 3,449,279 (150)

Broad-spectrum virus resistance in transgenic plants expressing pokeweed antiviral protein. [PDF]

Proc Natl Acad Sci U S A, 1993
Lodge JK, Kaniewski WK, Tumer NE.
europepmc   +1 more source

A pokeweed antiviral protein gene in roots of Phytolacca americana.

Acta virologica, 2004
Y, Zhao, X, Wang, G, Zhou, H, Li
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Shared germline-biased plasmablast clonotypes shape early neutralizing antibody responses during acute Chikungunya virus infection. [PDF]

Front Immunol
Dixit K, Nayak K, Saini MK, Qamar S, Bajpai P, Reddy ES, Ameer S, Dhar Dubey V, Pervez M, Kohli S, Gottimukkala K, Gupta S, Khan N, Maheshwari D, Akhtar NS, Chawla YM, Rai RC, Sagar R, Islamuddin M, Khan WH, Mishra N, Patel AK, Sunil S, Lodha R, Jain V, Ray P, Murali-Krishna K, Saini K, Kumar S, Chandele A.   +29 more
europepmc   +1 more source

Pharmacological Effects of Humic Substances and Their Signaling Mechanisms. [PDF]

Molecules
Zykova MV, Trofimova ES, Azarkina LA, Lasukova TV, Mihalyov DA, Drygunova LA, Danilets MG, Ligacheva AA, Tsupko AV, Bashirov SR, Belousov MV.   +10 more
europepmc   +1 more source

A safe, T cell-inducing heterologous vaccine against elephant endotheliotropic herpesvirus in a proof-of-concept study. [PDF]

Nat Commun
Maehr T, Lopez J, Drake G, Ferreira FM, Fraser R, Mckown R, Kailath R, Morris S, Chambers A, Graves LP, Walker SL, Dastjerdi A, Edwards KL, Nakaya HI, Steinbach F.   +14 more
europepmc   +1 more source

A possible mechanism for the antiviral activity of pokeweed antiviral protein

Physiological and Molecular Plant Pathology, 1993
Abstract The mechanism by which pokeweed antiviral protein (PAP) inhibits the infection of tobacco by TMV was investigated. The N-glycosidase activity of PAP was measured using a combination of aniline treatment to cleave the rRNA at the depurinated site, gel electrophoresis and Northern blot hybridization using a probe specific for the 3′ end of ...
Zhao-chun Chen, John F. Antoniw, Raymond F. White   +2 more
exaly   +3 more sources

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Requirements for antiribosomal activity of pokeweed antiviral protein

Biochimica Et Biophysica Acta Gene Regulatory Mechanisms, 1983
It has been known for some time that pokeweed antiviral protein acts by enzymatically inhibiting protein synthesis on eucaryotic ribosome systems. The site of this action is known to be the ribosome itself. In this paper we show that the pokeweed antiviral protein reaction against ribosomes is a strong function of salt concentrations, where 160 mM K ...
J D Robertus
exaly   +3 more sources

Pokeweed antiviral protein: a potential nonspermicidal prophylactic antiviral agent

Fertility and Sterility, 2001
To investigate the effects of pokeweed antiviral protein (PAP), a 29-kDa anti-human immunodeficiency virus (HIV) protein purified from the leaves of Phytolacca americana, on human sperm function.Prospective, controlled study.Reproductive biology department.Seven sperm donors.Human sperm and female genital tract epithelial cells were exposed to PAP ...
Osmond J D'Cruz, O J D'Cruz
exaly   +3 more sources

Reversal of the inhibitory effects of the pokeweed antiviral protein upon protein synthesis

Nucleic Acids and Protein Synthesis, 1981
Protein synthesis directed by natural mRNA is more sensitive to the inhibitory action of the pokeweed antiviral protein than synthesis directed by poly-(uridylic acid). Investigations into the nature of this difference revealed that pokeweed antiviral protein does not inhibit the initiation stage of protein synthesis and that the expression of pokeweed
J D Irvin
exaly   +3 more sources

Expression of pokeweed (Phytolacca americana) antiviral protein cDNA in Escherichia coli and its antiviral activity

Physiological and Molecular Plant Pathology, 1993
Abstract Two DNA constructs encoding the pokeweed antiviral protein (PAP), one encoding PAP and its signal peptide and the other encoding PAP, were made using polymerase chain reactions (PCR), inserted into the expression vector pKK233-2 and transformed into Escherichia coli JM109 cells.
Zhao-chun Chen, John F. Antoniw, Quan Lin, Raymond F. White   +3 more
openaire   +2 more sources