Results 81 to 90 of about 737,468 (299)

Intermediate filaments promote glioblastoma cell invasion by controlling nuclear deformations and mechanosensitive expression of MMP14

open access: yesCell Reports
Summary: Glioblastoma (GBM), the most aggressive primary brain tumor, is marked by high invasiveness that enables resistance to current therapies. Single-cell RNA sequencing analysis reveals that elevated expression of glial intermediate filament (IF ...
Emma J. van Bodegraven   +18 more
doaj   +1 more source

Crosstalk between NDR kinase pathways coordinates cell cycle dependent actin rearrangements

open access: yesCell Division, 2011
Regulation of cytoskeletal remodeling is essential for cell cycle transitions. In fission yeast two NDR kinase signaling cascades, MOR and SIN, regulate the actin cytoskeleton to promote polarized growth during interphase and cytokinesis respectively ...
Gupta Sneha, McCollum Dannel
doaj   +1 more source

Polarity sensitive circuit Patent [PDF]

open access: yes, 1968
Electric circuit for reversing direction of current ...
Smith, L. S.
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Applying mechanical forces on Drosophila tissues in vivo using the StretchCo, a 3D-printable device

open access: yesSTAR Protocols
Summary: Applying mechanical forces to tissues helps to understand morphogenesis and homeostasis. Additionally, recording the dynamics of living tissues under mechanical constraints is needed to explore tissue biomechanics. Here, we present a protocol to
Mélanie Gracia   +8 more
doaj   +1 more source

Political Left and Right: Our Hands-On Logic

open access: yesJournal of Social and Political Psychology, 2014
The origins and immediate vitality of the left/right divide which emerged in French revolutionary politics from 1789 can only be understood against the background of a much older classification dynamic based on the primacy of the right hand, first ...
Frits Bienfait, Walter E. A. van Beek
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Seed Morphological Analysis in Species of Vitis and Relatives

open access: yesHorticulturae
Seed shape descriptions of species of Vitis have traditionally been based on adjectives comparing overall shape with geometric figures, such as oval, elongated oval, and pear-shaped, corresponding to higher values of the Stummer index (lower aspect ratio)
José Javier Martín-Gómez   +6 more
doaj   +1 more source

Identification of Lightning Strike on 500-kV Transmission Line Based on the Time-Domain Parameters of a Traveling Wave

open access: yesIEEE Access, 2016
This paper presents a novel and analytical approach to identifying a lightning strike after it has struck an overhead transmission line. The identification method is mainly based on the traveling waves' time-domain parameters, such as polarity, amplitude,
Yadong Liu   +6 more
doaj   +1 more source

Large-Scale Goodness Polarity Lexicons for Community Question Answering

open access: yes, 2017
We transfer a key idea from the field of sentiment analysis to a new domain: community question answering (cQA). The cQA task we are interested in is the following: given a question and a thread of comments, we want to re-rank the comments so that the ...
Church Kenneth Ward   +5 more
core   +1 more source

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