Results 1 to 10 of about 71,443 (187)

Characterization of environmental and clinical surveillance inputs to support prospective integrated modeling of the polio endgame. [PDF]

PLOS Global Public Health
National, regional, and global poliovirus surveillance needs continue to expand and evolve. The 1988 global resolution to eradicate polio necessitated the creation and support for a global poliovirus surveillance system able to identify poliovirus ...
Kamran Badizadegan, Kimberly M Thompson
doaj   +2 more sources

Sporadic detection of vaccine-derived poliovirus type 2 using next-generation sequencing in Canadian wastewater in August of 2022 [PDF]

Scientific Reports
In July 2022, an unvaccinated young adult living in Rockland County, New York became paralyzed due to a vaccine-derived poliovirus type 2 (VDPV2) infection that was internationally transmitted. Wastewater surveillance in New York State uncovered VDPV2 in
Grace E. Seo, Russell Mandes, Nathan D. Wright, Justin P. Hawkins, Anneliese Landgraff, Ravinder Lidder, Umar Mohammed, Chand S. Mangat, Anne-Sophie Michel, Judith Fafard, Darian Hole, Andrea D. Tyler, Marli Vlok, Elsie Grudeski, Tim F. Booth, Anna Majer   +15 more
doaj   +2 more sources

Excretion and clearance of Sabin-like type 3 poliovirus in a child diagnosed with severe combined immunodeficiency [PDF]

Human Vaccines & Immunotherapeutics
Children with primary immunodeficiency disorder (PID) are at higher risk of developing vaccine-associated paralytic poliomyelitis (VAPP) or vaccine-derived polioviruses (VDPV) infection when inadvertently expose to poliovirus vaccine, oral (OPV). A pilot
Ning Yao, Yang Liu, Zhi-Yong Zhang, Min Tian, Wu-Juan Xie, Hua Zhao, Hong Yang, Lance E. Rodewald, Ning Wen, Zun-Dong Yin, Fu-Zhen Wang, Qing Wang, Jia-Wei Xu   +12 more
doaj   +2 more sources

Community surveillance after detection of poliovirus in the environment in London, United Kingdom, October 2022 to April 2023 [PDF]

Eurosurveillance
Background Vaccine-derived polioviruses (VDPVs) continue to circulate internationally, causing sporadic cases and outbreaks of paralytic polio in countries certified as polio-free.
Maria Zambon
doaj   +2 more sources

Direct detection of polioviruses using a recombinant poliovirus receptor.

PLoS ONE, 2021
Polioviruses are positive-sense, single-stranded RNA picornaviruses and the principal cause of poliomyelitis. Global poliovirus surveillance has relied on poliovirus isolation in cells, which may take a minimum of 10 days, involves maintaining two cell ...
Nancy Gerloff, Mark Mandelbaum, Hong Pang, Nikail Collins, Brittani Brown, Hong Sun, Chelsea Harrington, Jessica Hecker, Chadi Agha, Cara C Burns, Everardo Vega   +10 more
doaj   +2 more sources

Deconvolving mutational patterns of poliovirus outbreaks reveals its intrinsic fitness landscape. [PDF]

, 2020
Vaccination has essentially eradicated poliovirus. Yet, its mutation rate is higher than that of viruses like HIV, for which no effective vaccine exists.
Barton, John P, Chakraborty, Arup K, McKay, Matthew R, Quadeer, Ahmed A   +3 more
core   +3 more sources

Does IPV Boost Intestinal Immunity among Children under Five Years of Age? An Experience from Pakistan

Vaccines, 2023
The oral poliovirus vaccine (OPV) has been the mainstay of polio eradication, especially in low-income countries, and its use has eliminated wild poliovirus type 2.
Muhammad Atif Habib, Sajid Bashir Soofi, Imtiaz Hussain, Imran Ahmed, Zamir Hussain, Rehman Tahir, Saeed Anwar, Simon Cousens, Zulfiqar A. Bhutta   +8 more
doaj   +1 more source

Risk Assessment and Virological Monitoring Following an Accidental Exposure to Concentrated Sabin Poliovirus Type 3 in France, November 2018

Vaccines, 2020
The safe and secure containment of infectious poliovirus (PV) in facilities where live PV are handled is the condition to achieve and maintain poliomyelitis eradication.
Marion Jeannoël, Denise Antona, Clément Lazarus, Bruno Lina, Isabelle Schuffenecker   +4 more
doaj   +1 more source

Whole Genome Sequencing of Enterovirus species C Isolates by High-throughput Sequencing: Development of Generic Primers

Frontiers in Microbiology, 2016
Enteroviruses are among the most common viruses infecting humans and can cause diverse clinical syndromes ranging from minor febrile illness to severe and potentially fatal diseases.
Maël Bessaud, Maël Bessaud, Maël Bessaud, Serge Sadeuh-Mba, Marie-Line Joffret, Marie-Line Joffret, Marie-Line Joffret, Richter Razafindratsimandresy, Patsy Polston, Patsy Polston, Romain Volle, Romain Volle, Mala Rakoto-Andrianarivelo, Bruno Blondel, Bruno Blondel, Richard Njouom, Francis Delpeyroux, Francis Delpeyroux, Francis Delpeyroux   +18 more
doaj   +1 more source

Inhibition of translation by poliovirus: Inactivation of a specific initiation factor [PDF]

, 1978
Translation of vesicular stomatitis virus (VSV) mRNA, like host mRNA translation, is inhibited in cells infected with poliovirus. To study the mechanism of poliovirus-induced inhibition of protein synthesis, we prepared extracts from poliovirus-infected ...
Baltimore, David, Leong, Kahan, Rose, John K., Trachsel, Hans   +3 more
core   +1 more source