Results 51 to 60 of about 86,994 (300)

Establishment of a Poliovirus Containment Program and Containment Certification Process for Poliovirus-Essential Facilities, United States 2017–2022

open access: yesPathogens
Upon declaration of poliovirus (PV) type 2 eradication in 2015, the World Health Organization (WHO) published PV containment requirements in the Global Action Plan III (GAPIII) for mitigating the risk of a facility-associated release post eradication. In
Christy Ottendorfer   +8 more
doaj   +1 more source

Importation and Circulation of Vaccine-Derived Poliovirus Serotype 2, Senegal, 2020–2021

open access: yesEmerging Infectious Diseases, 2022
Environmental surveillance for poliovirus is increasingly used in poliovirus eradication efforts as a supplement to acute flaccid paralysis (AFP) surveillance. Environmental surveillance was officially established in 2017 in Senegal, where no poliovirus
Martin Faye   +13 more
doaj   +1 more source

Insights into neutralization of animal viruses gained from study of influenza virus [PDF]

open access: yes, 1991
It has long been known that the binding of antibodies to viruses can result in a loss of infectivity, or neutralization, but little is understood of the mechanism or mechanisms of this process.
Colonno   +17 more
core   +2 more sources

Prolonged Excretion of Poliovirus among Individuals with Primary Immunodeficiency Disorder: An Analysis of the World Health Organization Registry

open access: yesFrontiers in Immunology, 2017
Individuals with primary immunodeficiency disorder may excrete poliovirus for extended periods and will constitute the only remaining reservoir of virus after eradication and withdrawal of oral poliovirus vaccine.
Grace R. Macklin   +8 more
semanticscholar   +1 more source

Surveillance of Acute Flaccid Paralysis (AFP) in Greece: 2008–2024

open access: yesPathogens
As part of the WHO’s Global Polio Eradication Initiative, acute flaccid paralysis (AFP) surveillance in children under 15 years old is crucial for monitoring the emergence of polioviruses and tracking Non-Polio Enteroviruses (NPEVs).
Stavroula Labropoulou   +7 more
doaj   +1 more source

Detection of minority variants within bovine respiratory syncytial virus populations using oligonucleotide-based microarrays [PDF]

open access: yes, 2008
Microarray technology, originally developed for highly parallel examination of gene expression is regarded as a potential tool in prognosis and diagnosis.
Baranowski, Eric   +4 more
core   +2 more sources

Patients with Primary Immunodeficiencies Are a Reservoir of Poliovirus and a Risk to Polio Eradication

open access: yesFrontiers in Immunology, 2017
Immunodeficiency-associated vaccine-derived polioviruses (iVDPVs) have been isolated from primary immunodeficiency (PID) patients exposed to oral poliovirus vaccine (OPV).
A. Aghamohammadi   +28 more
semanticscholar   +1 more source

Poliomyelitis amidst the COVID-19 pandemic in Africa: Efforts, challenges and recommendations

open access: yesClinical Epidemiology and Global Health, 2022
Poliomyelitis is the leading infectious cause of acute flaccid paralysis among children under five years of age, caused by the Wild Poliovirus, with no medical cure other than prevention through vaccination.
Olivier Uwishema   +7 more
doaj   +1 more source

Inhibition of cellular protein secretion by norwalk virus nonstructural protein p22 requires a mimic of an endoplasmic reticulum export signal. [PDF]

open access: yes, 2013
Protein trafficking between the endoplasmic reticulum (ER) and Golgi apparatus is central to cellular homeostasis. ER export signals are utilized by a subset of proteins to rapidly exit the ER by direct uptake into COPII vesicles for transport to the ...
Crawford, Sue E.   +4 more
core   +2 more sources

Multimodal Imaging Reveals Cerebral Microcirculation Dynamics and Mechanisms in Mouse Central Nervous System After Intranasal Infection With Recombinant Pseudorabies Virus

open access: yesAdvanced Science, EarlyView.
Multi‐modality imaging strategy applied to PRV‐induced central nervous system infection enables dynamic visualization of cerebrovascular dysfunction, including hyperemia, hypoperfusion, and vascular remodeling. These changes are linked to microglial activation and impaired angiogenesis, providing mechanistic insight into PRV neuropathogenesis and ...
Shuting Ling   +13 more
wiley   +1 more source

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