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Research Progress Towards Poliovirus Virus-like Particle Vaccines: A Review [PDF]

open access: yesVaccines
Poliovirus (PV), a historically significant enterovirus responsible for severe paralytic diseases, has seen its incidence dramatically reduced through widespread vaccination efforts, propelling global eradication initiatives.
Taoli Han   +5 more
doaj   +2 more sources

Safety of Sabin-Strain Inactivated Poliovirus Vaccine Administered Alone or Concomitantly with Other Vaccines: A Population-Based Post-Marketing Surveillance Study [PDF]

open access: yesVaccines
Background/Objectives: Sabin-strain inactivated poliovirus vaccine has been increasingly incorporated into routine immunization programs as part of the global strategy to eradicate poliomyelitis.
Lin Chang   +5 more
doaj   +2 more sources

Factors associated with the circulation of vaccine-derived polioviruses in children under five in Kilwa, Haut-Katanga province, Democratic Republic of Congo, 2022–2023 [PDF]

open access: yesBMC Infectious Diseases
Introduction Since the World Health Organization declared the African region free of wild poliovirus in August 2020, vaccine-derived polioviruses (VDPV) have remained the only form of poliovirus still circulating on the continent, including in the ...
Jean Blaise Yobo Iyala   +7 more
doaj   +2 more sources

Development and Validation of a Quantitative RT-qPCR Panel for the Detection and Monitoring of Polioviruses in Wastewater Samples [PDF]

open access: yesMicroorganisms
Clusters of acute flaccid paralysis (AFP) caused by oral vaccine-derived poliovirus (VDPV) in 2022 and sporadic outbreaks in New York and Gaza highlight the ongoing risk of polio, alongside the persistent global threat posed by wild-type poliovirus. This
Linnet Immaraj   +8 more
doaj   +2 more sources

Advances and challenges in poliomyelitis vaccines: a comprehensive review of development, production, and global deployment [PDF]

open access: yesFrontiers in Public Health
Poliomyelitis has been a significant global health challenge for centuries. Since the launch of the Global Polio Eradication Initiative (GPEI) in 1988, remarkable progress has been achieved, with wild poliovirus (WPV) cases reduced by over 99%.
Jia Liang, Qi Zhang, Yanan Li, Lili Wang
doaj   +2 more sources

Long-Term Persistence of Anti-Poliovirus Antibody Titers After Two-Dose Booster Immunization with Conventional Inactivated Poliovirus Vaccine Among Japanese Adults: 10-Year Observational Study [PDF]

open access: yesVaccines
Background/Objectives: Most Japanese adults received two doses of the oral polio vaccine (OPV) during childhood as part of the national immunization program. However, these two doses are considered suboptimal by global standards.
Shinji Fukushima   +4 more
doaj   +2 more sources

Emergence of vaccine-derived poliovirus type 2 after using monovalent type 2 oral poliovirus vaccine in an outbreak response, Philippines

open access: yesWestern Pacific Surveillance and Response, 2022
Objective: In response to an outbreak of circulating vaccine-derived poliovirus (cVDPV) type 2 in the Philippines in 2019–2020, several rounds of supplementary immunization activities using the monovalent type 2 oral poliovirus vaccine (OPV) were ...
SweetC B Alipon   +12 more
doaj   +1 more source

Poliomyelitis amidst the COVID-19 pandemic in Africa: Efforts, challenges and recommendations

open access: yesClinical Epidemiology and Global Health, 2022
Poliomyelitis is the leading infectious cause of acute flaccid paralysis among children under five years of age, caused by the Wild Poliovirus, with no medical cure other than prevention through vaccination.
Olivier Uwishema   +7 more
doaj   +1 more source

PREVALENCE OF NEUTRALIZING ANTIBODIES AGAINST POLIOVIRUS 1, 2, AND 3 IN HEALTHCARE PROFESSIONALS AGED 20-50 YEARS

open access: yesRevista Paulista de Pediatria, 2021
Objective: To describe the prevalence of neutralizing antibodies against poliovirus (PV1, PV2, and PV3) in blood samples of healthcare professionals aged 20 to 50 years.
José Cassio de Moraes   +2 more
doaj   +2 more sources

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